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PDB: 1988 件

4TY0
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Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with linear intermediate 5' pppA(3',5')pG
分子名称: ACETATE ION, Cyclic AMP-GMP synthase, MAGNESIUM ION, ...
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
4TXZ
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BU of 4txz by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase in complex with nonhydrolyzable GTP
分子名称: Cyclic AMP-GMP synthase, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
3I0N
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BU of 3i0n by Molmil
Structure of the S. pombe Nbs1 FHA/BRCT-repeat domain
分子名称: DNA repair and telomere maintenance protein nbs1, GLYCEROL
著者Clapperton, J.A, Lloyd, J, Chapman, J.R, Jackson, S.P, Smerdon, S.J.
登録日2009-06-25
公開日2009-10-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A supramodular FHA/BRCT-repeat architecture mediates Nbs1 adaptor function in response to DNA damage
Cell(Cambridge,Mass.), 139, 2009
7N64
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BU of 7n64 by Molmil
SARS-CoV-2 Spike (2P) in complex with G32R7 Fab (RBD and NTD local reconstruction)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, G32R7 Fab heavy chain, ...
著者Windsor, I.W, Jenni, S, Tong, P, Gautam, A.K, Wesemann, D.R, Harrison, S.C.
登録日2021-06-07
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.
Biorxiv, 2021
7N62
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BU of 7n62 by Molmil
SARS-CoV-2 Spike (2P) in complex with C12C9 Fab (NTD local reconstruction)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, C12C9 Fab heavy chain, C12C9 Fab light chain, ...
著者Windsor, I.W, Jenni, S, Bajic, G, Tong, P, Gautam, A.K, Wesemann, D.R, Harrison, S.C.
登録日2021-06-07
公開日2021-08-04
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Memory B cell repertoire for recognition of evolving SARS-CoV-2 spike.
Biorxiv, 2021
6Q0I
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BU of 6q0i by Molmil
Inferred intermediate I-7 (I-7-6) of the human antibody lineage 652 in complex with influenza hemagglutinin head domain of A/Beijing/262/95(H1N1)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab lambda chain, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2019-08-01
公開日2019-12-18
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.702 Å)
主引用文献Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6Q1K
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BU of 6q1k by Molmil
Inferred intermediate I-7 of the human antibody lineage 652
分子名称: Fab heavy chain, Fab lambda light chain, GLYCEROL
著者McCarthy, K.R, Harrison, S.C.
登録日2019-08-05
公開日2019-12-18
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6W8P
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BU of 6w8p by Molmil
Structure of membrane protein with ions
分子名称: Endosomal/lysosomal potassium channel TMEM175, POTASSIUM ION
著者Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
登録日2020-03-21
公開日2021-08-04
最終更新日2024-10-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Structure of membrane protein with ions
To Be Published
6W8N
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BU of 6w8n by Molmil
Structure of a trans-membrane protein
分子名称: Endosomal/lysosomal potassium channel TMEM175
著者Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
登録日2020-03-20
公開日2021-08-04
最終更新日2024-10-30
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of a trans-membrane protein
To Be Published
6W8O
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BU of 6w8o by Molmil
Structure of an Apo membrane protein
分子名称: Endosomal/lysosomal potassium channel TMEM175
著者Shen, C, Fu, T.M, Wang, L.F, Rawson, S, Wu, H.
登録日2020-03-20
公開日2021-08-04
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure of an Apo membrane protein
To Be Published
6Q0O
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BU of 6q0o by Molmil
human antibody H2227 lineage 652 in complex with influenza hemagglutinin head domain of A/Solomon Islands/3/2006(H1N1)
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
著者McCarthy, K.R, Harrison, S.C.
登録日2019-08-02
公開日2019-12-18
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Affinity maturation in a human humoral response to influenza hemagglutinin.
Proc.Natl.Acad.Sci.USA, 2019
6S2C
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BU of 6s2c by Molmil
Acquired functional capsid structures in metazoan totivirus-like dsRNA virus.
分子名称: Capsid protein
著者Okamoto, K, Larsson, S.D.D, Maia, R.N.C.F, Murata, K, Hajdu, J, Iwasaki, K, Miyazaki, N.
登録日2019-06-20
公開日2020-04-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Acquired Functional Capsid Structures in Metazoan Totivirus-like dsRNA Virus.
Structure, 28, 2020
5AG6
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BU of 5ag6 by Molmil
CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A THIAZOLIDINONE LIGAND
分子名称: (2R)-2-(4-hydroxy-3-methoxyphenyl)-3-(pyridin-2-ylmethyl)-1,3-thiazolidin-4-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA
著者Robinson, D.A, Spinks, D, Smith, V.C, Thompson, S, Smith, A, Torrie, L.S, McElroy, S.P, Brand, S, Brenk, R, Frearson, J.A, Read, K.D, Wyatt, P.G, Gilbert, I.H.
登録日2015-01-29
公開日2015-10-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Chemmedchem, 10, 2015
2PKD
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BU of 2pkd by Molmil
Crystal structure of CD84: Insite into SLAM family function
分子名称: CHLORIDE ION, SLAM family member 5
著者Yan, Q, Malashkevich, V.N, Fedorov, A, Cao, E, Lary, J.W, Cole, J.L, Nathenson, S.G, Almo, S.C.
登録日2007-04-17
公開日2007-06-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.043 Å)
主引用文献Structure of CD84 provides insight into SLAM family function.
Proc.Natl.Acad.Sci.Usa, 104, 2007
7M6T
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BU of 7m6t by Molmil
Crystal structure of SOCS2/ElonginB/ElonginC bound to a non-canonical peptide that enhances phospho-peptide binding
分子名称: Elongin-B, Elongin-C, Non-canonical peptide F3, ...
著者Kershaw, N.J, Li, K, Linossi, E.M, Nicholson, S.E.
登録日2021-03-26
公開日2021-10-13
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.194 Å)
主引用文献Discovery of an exosite on the SOCS2-SH2 domain that enhances SH2 binding to phosphorylated ligands.
Nat Commun, 12, 2021
4TXY
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BU of 4txy by Molmil
Crystal structure of Vibrio cholerae DncV cyclic AMP-GMP synthase, a prokaryotic cGAS homolog
分子名称: Cyclic AMP-GMP synthase, MAGNESIUM ION
著者Kranzusch, P.J, Lee, A.S.Y, Wilson, S.C, Solovykh, M.S, Vance, R.E, Berger, J.M, Doudna, J.A.
登録日2014-07-07
公開日2014-08-13
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.0001 Å)
主引用文献Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity.
Cell, 158, 2014
5F6I
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BU of 5f6i by Molmil
Crystal Structure of Tier 2 Neutralizing Antibody DH428 from a Rhesus Macaque
分子名称: DH428 Antibody Heavy Chain, DH428 Antibody Light Chain
著者Fera, D, Harrison, S.C.
登録日2015-12-06
公開日2016-01-13
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (2.32 Å)
主引用文献Structural Constraints of Vaccine-Induced Tier-2 Autologous HIV Neutralizing Antibodies Targeting the Receptor-Binding Site.
Cell Rep, 14, 2016
5AG5
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BU of 5ag5 by Molmil
CRYSTAL STRUCTURE OF LEISHMANIA MAJOR N-MYRISTOYLTRANSFERASE (NMT) WITH BOUND MYRISTOYL-COA AND A THIAZOLIDINONE LIGAND
分子名称: (2R)-3-benzyl-2-(1H-indazol-5-yl)-1,3-thiazolidin-4-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, TETRADECANOYL-COA
著者Robinson, D.A, Spinks, D, Smith, V.C, Thompson, S, Smith, A, Torrie, L.S, McElroy, S.P, Brand, S, Brenk, R, Frearson, J.A, Read, K.D, Wyatt, P.G, Gilbert, I.H.
登録日2015-01-29
公開日2015-10-07
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Development of Small-Molecule Trypanosoma Brucei N-Myristoyltransferase Inhibitors: Discovery and Optimisation of a Novel Binding Mode.
Chemmedchem, 10, 2015
2QDF
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BU of 2qdf by Molmil
Structure of N-terminal domain of E. Coli YaeT
分子名称: MAGNESIUM ION, Outer membrane protein assembly factor yaeT
著者Kim, S, Malinverni, J.C, Sliz, P, Silhavy, T.J, Harrison, S.C, Kahne, D.
登録日2007-06-20
公開日2007-09-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure and function of an essential component of the outer membrane protein assembly machine.
Science, 317, 2007
2QCZ
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BU of 2qcz by Molmil
Structure of N-terminal domain of E. Coli YaeT
分子名称: Outer membrane protein assembly factor yaeT
著者Kim, S, Malinverni, J.C, Sliz, P, Silhavy, T.J, Harrison, S.C, Kahne, D.
登録日2007-06-20
公開日2007-08-28
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structure and function of an essential component of the outer membrane protein assembly machine.
Science, 317, 2007
3ISD
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BU of 3isd by Molmil
Ternary complex of human DNA polymerase beta with an abasic site (THF): DAPCPP mismatch
分子名称: 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]adenosine, 5'-D(*CP*CP*GP*AP*CP*(3DR)P*GP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3', ...
著者Beard, W.A, Shock, D.D, Batra, V.K, Pedersen, L.C, Wilson, S.H.
登録日2009-08-25
公開日2009-09-15
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献DNA polymerase beta substrate specificity: side chain modulation of the "A-rule".
J.Biol.Chem., 284, 2009
2VML
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BU of 2vml by Molmil
The monoclinic structure of phycocyanin from Gloeobacter violaceus
分子名称: PHYCOCYANIN ALPHA CHAIN, PHYCOCYANIN BETA CHAIN, PHYCOCYANOBILIN
著者Murray, J.W, Benson, S, Barber, J.
登録日2008-01-28
公開日2008-03-25
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献The Structures of the Phycobiliproteins of Gloeobacter Violaceus
To be Published
8QYJ
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BU of 8qyj by Molmil
Human 20S proteasome assembly structure 1
分子名称: Proteasome assembly chaperone 1, Proteasome assembly chaperone 2, Proteasome assembly chaperone 3, ...
著者Schulman, B.A, Hanna, J.W, Harper, J.W, Adolf, F, Du, J, Rawson, S.D, Walsh Jr, R.M, Goodall, E.A.
登録日2023-10-26
公開日2024-02-21
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.73 Å)
主引用文献Visualizing chaperone-mediated multistep assembly of the human 20S proteasome.
Nat.Struct.Mol.Biol., 31, 2024
5I7C
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BU of 5i7c by Molmil
Centrosomin-motif 2 (CM2) domain of Drosophila melanogaster Centrosomin (Cnn)
分子名称: Centrosomin, ZINC ION
著者Feng, Z, Cottee, M.A, Johnson, S, Lea, S.M.
登録日2016-02-17
公開日2017-03-08
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.804 Å)
主引用文献Structural Basis for Mitotic Centrosome Assembly in Flies.
Cell, 169, 2017
5HCC
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BU of 5hcc by Molmil
Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3.
分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Jore, M.M, Johnson, S, Lea, S.M.
登録日2016-01-04
公開日2016-03-30
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structural basis for therapeutic inhibition of complement C5.
Nat.Struct.Mol.Biol., 23, 2016

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