5HCC

Ternary complex of human Complement C5 with Ornithodoros moubata OmCI and Dermacentor andersoni RaCI3.

Summary for 5HCC

• Entry DOI: 10.2210/pdb5hcc/pdb
• Descriptor: Complement C5, Complement inhibitor, Dermacentor andersoni RaCI3, ... (9 entities in total)
• Functional Keywords: complement, inflammation, inhibitor, tick, immune system
• Biological source: Ornithodoros moubata (Soft tick); More
• Total number of polymer chains: 4
• Total formula weight: 214441.78

Authors

Jore, M.M.,Johnson, S.,Lea, S.M. (deposition date: 2016-01-04, release date: 2016-03-30, Last modification date: 2024-01-10)

• Primary citation: Jore, M.M.,Johnson, S.,Sheppard, D.,Barber, N.M.,Li, Y.I.,Nunn, M.A.,Elmlund, H.,Lea, S.M.; Structural basis for therapeutic inhibition of complement C5.; Nat.Struct.Mol.Biol., 23:378-386, 2016; PubMed: 27018802; DOI: 10.1038/nsmb.3196

Experimental method

X-RAY DIFFRACTION (2.59 Å)