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PDB: 452 件

2F5Y
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Crystal Structure of the PDZ Domain from Human RGS-3
分子名称: SULFATE ION, regulator of G-protein signalling 3 isoform 1
著者Ugochukwu, E, Berridge, G, Johansson, C, Smee, C, Savitsky, P, Burgess, N, Colebrook, S, Yang, X, Elkins, J, Doyle, D, Turnbull, A, Papagrigoriou, E, Debreczeni, J, Bunkoczi, G, Gorrec, F, von Delft, F, Arrowsmith, C, Sundstrom, M, Weigelt, J, Edwards, A, Structural Genomics Consortium (SGC)
登録日2005-11-28
公開日2005-12-13
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.39 Å)
主引用文献Crystal Structure of the PDZ Domain from Human RGS-3
To be Published
2FE5
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The Crystal Structure of the Second PDZ Domain of Human DLG3
分子名称: GLYCEROL, Presynaptic protein SAP102, SULFATE ION
著者Ugochukwu, E, Phillips, C, Schoch, G, Berridge, G, Salah, E, Colebrook, S, Smee, C, Savitsky, P, Bray, J, Elkins, J, Doyle, D, Bunkoczi, G, Debreczeni, J, Turnbull, A, Gorrec, F, von Delft, F, Sundstrom, M, Arrowsmith, C, Weigelt, J, Edwards, A, Structural Genomics Consortium (SGC)
登録日2005-12-15
公開日2005-12-27
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.1 Å)
主引用文献The Crystal Structure of the Second PDZ Domain of Human DLG3
To be Published
2UW2
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Crystal structure of human ribonucleotide reductase subunit R2
分子名称: FE (III) ION, RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT
著者Welin, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ehn, M, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Kotenyova, T, Magnusdottir, A, Moche, M, Nilsson-Ehle, P, Nyman, T, Persson, C, Sagemark, J, Sundstrom, M, Stenmark, P, Uppenberg, J, Thorsell, A.G, Van Den Berg, S, Wallden, K, Weigelt, J, Nordlund, P.
登録日2007-03-16
公開日2007-04-03
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published
2UVQ
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Crystal structure of human uridine-cytidine kinase 1 in complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, URIDINE-CYTIDINE KINASE 1
著者Kosinska, U, Stenmark, P, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Edwards, A, Ericsson, U.B, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg Schiavone, L, Hogbom, M, Johansson, I, Karlberg, T, Kotenyova, T, Moche, M, Nilsson, M.E.P, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Uppenberg, J, Uppsten, M, Thorsell, A.G, Van Den Berg, S, Weigelt, J, Welin, M, Nordlund, P.
登録日2007-03-13
公開日2007-03-27
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of Human Uridine-Cytidine Kinase 1
To be Published
2VD6
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Human adenylosuccinate lyase in complex with its substrate N6-(1,2- Dicarboxyethyl)-AMP, and its products AMP and fumarate.
分子名称: 2-[9-(3,4-DIHYDROXY-5-PHOSPHONOOXYMETHYL-TETRAHYDRO-FURAN-2-YL)-9H-PURIN-6-YLAMINO]-SUCCINIC ACID, ADENOSINE MONOPHOSPHATE, ADENYLOSUCCINATE LYASE, ...
著者Stenmark, P, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nilsson, M, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Welin, M, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2007-09-30
公開日2007-10-23
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Human Adenylosuccinate Lyase in Complex with its Substrate N6-(1,2-Dicarboxyethyl)-AMP, and its Products AMP and Fumarate.
To be Published
2V30
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Human orotidine 5'-phosphate decarboxylase domain of uridine monophospate synthetase (UMPS) in complex with its product UMP.
分子名称: OROTIDINE 5'-PHOSPHATE DECARBOXYLASE, URIDINE-5'-MONOPHOSPHATE
著者Moche, M, Ogg, D, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den Berg, S, Weigelt, J, Welin, M, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2007-06-10
公開日2007-07-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Crystal Structure of Human Orotidine 5'-Decarboxylase Domain of Human Uridine Monophosphate Synthetase (Umps)
To be Published
2V40
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Human Adenylosuccinate synthetase isozyme 2 in complex with GDP
分子名称: ADENYLOSUCCINATE SYNTHETASE ISOZYME 2, GUANOSINE-5'-DIPHOSPHATE
著者Welin, M, Moche, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, Tresaugues, L, van den Berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2007-06-27
公開日2007-07-10
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Human Adenylosuccinate Synthetase Isozyme 2 in Complex with Gdp
To be Published
2UZ9
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Human guanine deaminase (guaD) in complex with zinc and its product Xanthine.
分子名称: GUANINE DEAMINASE, XANTHINE, ZINC ION
著者Moche, M, Welin, M, Arrowsmith, C, Berglund, H, Busam, R, Collins, R, Dahlgren, L.G, Edwards, A, Flodin, S, Flores, A, Graslund, S, Hammarstrom, M, Hallberg, B.M, Holmberg-Schiavone, L, Johansson, I, Kallas, A, Karlberg, T, Kotenyova, T, Lehtio, L, Nyman, T, Ogg, D, Persson, C, Sagemark, J, Stenmark, P, Sundstrom, M, Thorsell, A.G, van den berg, S, Weigelt, J, Nordlund, P, Structural Genomics Consortium (SGC)
登録日2007-04-26
公開日2007-05-08
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Human Guanine Deaminase (Guad) in Complex with Zinc and its Product Xhantine
To be Published
2VRE
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crystal structure of human peroxisomal delta3,5,delta2,4-dienoyl coa isomerase
分子名称: CHLORIDE ION, DELTA(3,5)-DELTA(2,4)-DIENOYL-COA ISOMERASE
著者Yue, W, Guo, K, von Delft, F, Pilka, E, Murray, J, Roos, A, Kochan, G, Bountra, C, Arrowsmith, C, Wikstrom, M, Edwards, A, Oppermann, U.
登録日2008-03-31
公開日2008-04-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Crystal Structure of Human Peroxisomal Delta3,5, Delta2,4-Dienoyl Coa Isomerase (Ech1)
To be Published
2FV8
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The crystal structure of RhoB in the GDP-bound state
分子名称: GUANOSINE-5'-DIPHOSPHATE, Rho-related GTP-binding protein RhoB
著者Turnbull, A.P, Soundararajan, M, Smee, C, Johansson, C, Schoch, G, Gorrec, F, Bray, J, Papagrigoriou, E, von Delft, F, Weigelt, J, Edwards, A, Arrowsmith, C, Sundstrom, M, Doyle, D, Structural Genomics Consortium (SGC)
登録日2006-01-30
公開日2006-02-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The crystal structure of RhoB in the GDP-bound state
To be Published
6G4Q
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Structure of human ADP-forming succinyl-CoA ligase complex SUCLG1-SUCLA2
分子名称: 1,2-ETHANEDIOL, Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial, ...
著者Bailey, H.J, Shrestha, L, Rembeza, E, Sorrell, F.J, Newman, J, Strain-Damerell, C, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.
登録日2018-03-28
公開日2018-04-11
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献Structure of human ADP-forming succinyl-CoA ligase complex SUCLG1-SUCLA2
To Be Published
6GQD
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Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L
分子名称: 1,2-ETHANEDIOL, 5,6-DIHYDROURIDINE-5'-MONOPHOSPHATE, Galactose-1-phosphate uridylyltransferase, ...
著者Fairhead, M, Strain-Damerell, C, Kopec, J, Bezerra, G.A, Zhang, M, Burgess-Brown, N, von Delft, F, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W, Structural Genomics Consortium (SGC)
登録日2018-06-07
公開日2018-07-18
実験手法X-RAY DIFFRACTION (1.523 Å)
主引用文献Structure of human galactose-1-phosphate uridylyltransferase (GALT), with crystallization epitope mutations A21Y:A22T:T23P:R25L
To Be Published
2VX2
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Crystal structure of human enoyl Coenzyme A hydratase domain- containing protein 3 (ECHDC3)
分子名称: ENOYL-COA HYDRATASE DOMAIN-CONTAINING PROTEIN 3
著者Yue, W.W, Guo, K, Kochan, G, Pilka, E, Murray, J.W, Salah, E, Cocking, R, Sun, Z, Roos, A.K, Pike, A.C.W, Filippakopoulos, P, Arrowsmith, C, Wikstrom, M, Edwards, A, Bountra, C, Oppermann, U.
登録日2008-06-30
公開日2008-10-14
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Human Enoyl Coenzyme a Hydratase Domain-Containing Protein 3 (Echdc3)
To be Published
2KQ9
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Solution structure of DnaK suppressor protein from Agrobacterium tumefaciens C58. Northeast Structural Genomics Consortium target AtT12/Ontario Center for Structural Proteomics Target atc0888
分子名称: DnaK suppressor protein, ZINC ION
著者Wu, B, Yee, A, Fares, C, Lemak, A, Semest, A, Montelione, G.T, Arrowsmith, C, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP)
登録日2009-11-02
公開日2009-11-17
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution Structure of DnaK protein from Agrobacterium tumefaciens C58. Northeast Structural Genomics Consortium target AtT12/Ontario Center for Structural Proteomics Target atc0888
To be Published
2K4X
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Solution structure of 30S ribosomal protein S27A from Thermoplasma acidophilum
分子名称: 30S ribosomal protein S27ae, ZINC ION
著者Wu, B, Yee, A, Fares, C, Lemak, A, Semest, A, Arrowsmith, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG), Ontario Centre for Structural Proteomics (OCSP)
登録日2008-06-20
公開日2008-08-19
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献Solution structure of 30S ribosomal protein S27A from Thermoplasma acidophilum/Northeast Structural Genomics Consortium Target TaT88/Ontario Center for Structural Proteomics target ta1093
To be Published
2WM8
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Crystal structure of human magnesium-dependent phosphatase 1 of the haloacid dehalogenase superfamily (MGC5987)
分子名称: 1,2-ETHANEDIOL, MAGNESIUM-DEPENDENT PHOSPHATASE 1
著者Yue, W.W, Shafqat, N, Pike, A.C.W, Chaikuad, A, Bray, J.E, Pilka, E.W, Burgess-Brown, N, Hapka, E, Filippakopoulos, P, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
登録日2009-06-30
公開日2009-07-28
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Human Magnesium-Dependent Phosphatase 1 of the Haloacid Dehalogenase Superfamily (Mgc5987)
To be Published
4AKV
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Crystal structure of human sorting nexin 33 (SNX33)
分子名称: SORTING NEXIN-33, SULFATE ION
著者Oberholzer, A, Froese, D.S, Krojer, T, Shrestha, L, Filippakopoulos, P, Muniz, J.R.C, von Delft, F, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Yue, W.W.
登録日2012-02-29
公開日2012-08-01
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.651 Å)
主引用文献Structure of Human Sorting Nexin 33
To be Published
2XXZ
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Crystal structure of the human JMJD3 jumonji domain
分子名称: 1,2-ETHANEDIOL, 8-hydroxyquinoline-5-carboxylic acid, LYSINE-SPECIFIC DEMETHYLASE 6B, ...
著者Che, K.H, Yue, W.W, Krojer, T, Muniz, J.R.C, Ng, S.S, Tumber, A, Daniel, M, Burgess-Brown, N, Savitsky, P, Ugochukwu, E, Filippakopoulos, P, Arrowsmith, C, Weigelt, J, Edwards, A, Bountra, C, Oppermann, U.
登録日2010-11-12
公開日2010-11-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the Human Jmjd3 Jumonji Domain
To be Published
4AZ9
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Crystal structure of phox homology domain of human sorting nexin 24
分子名称: 1,2-ETHANEDIOL, SORTING NEXIN-24
著者Oberholzer, A.E, Kiyani, W, Krojer, T, Shrestha, L, von Delft, F, Froese, D.S, Chaikuad, A, Raynor, J, Arrowsmith, C, Edwards, A, Bountra, C, Yue, W.W.
登録日2012-06-24
公開日2012-10-10
最終更新日2018-01-24
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Crystal Structure of Phox Homology Domain of Human Sorting Nexin 24
To be Published
4AOT
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Crystal Structure of Human Serine Threonine Kinase-10 (LOK) Bound to GW830263A
分子名称: 1-(4-{methyl[2-({4-[(methylsulfonyl)methyl]phenyl}amino)pyrimidin-4-yl]amino}phenyl)-3-{3-[(4-methylpiperazin-1-yl)carbonyl]phenyl}urea, CHLORIDE ION, Serine/threonine-protein kinase 10
著者Elkins, J.M, Salah, E, Szklarz, M, Canning, P, von Delft, F, Yue, W, Liu, Y, Bountra, C, Arrowsmith, C, Edwards, A, Knapp, S.
登録日2012-03-29
公開日2012-04-11
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.33 Å)
主引用文献Crystal Structure of Human Serine Threonine Kinase-10 (Lok) Bound to Gw830263A
To be Published
2KEO
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Solution NMR structure of human protein HS00059, cytochrome-b5-like domain of the HERC2 E3 ligase. Northeast structural genomics consortium (NESG) target ht98a
分子名称: Probable E3 ubiquitin-protein ligase HERC2
著者Lemak, A, Gutmanas, A, Fares, C, Quyang, H, Li, Y, Montelione, G, Arrowsmith, C, Dhe-Paganon, S, Northeast Structural Genomics Consortium (NESG)
登録日2009-01-30
公開日2009-02-24
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR Structure of human protein HS00059
To be Published
2K54
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Solution NMR structure of protein Atu0742 from Agrobacterium Tumefaciens. Northeast Structural Genomics Consortium (NESG0) target AtT8. Ontario Center for Structural Proteomics target ATC0727 .
分子名称: Protein Atu0742
著者Lemak, A, Yee, A, Gutmanas, A, Fares, C, Semesi, A, Arrowsmith, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
登録日2008-06-24
公開日2008-08-19
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution structure of protein ATC0727 from Agrobacterium Tumefaciens.
To be Published
8VIS
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Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide
分子名称: 1,2-ETHANEDIOL, GLYCEROL, MAGNESIUM ION, ...
著者Fraser, B.J, Dong, A, Ilyassov, O, Kenney, T, Li, Y.Y, Seitova, A, Li, Y, Hejazi, Z, Edwards, A, Benard, F, Arrowsmith, C.
登録日2024-01-05
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Human TMPRSS11D complexed with a disulfide-linked autoinhibitory DDDDK peptide
To Be Published
8V1F
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TMPRSS2 complexed with the noncovalent inhibitor 6-amidino-2-napthol
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Fraser, B.J, Dong, A, Kutera, M, Seitova, A, Li, Y, Hutchinson, A, Edwards, A, Benard, F, Halabelian, L, Arrowsmith, C, Structural Genomics Consortium (SGC)
登録日2023-11-20
公開日2024-02-07
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献TMPRSS2 complexed with the noncovalent inhibitor 6-amidino-2-napthol
To Be Published
8V04
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High resolution TMPRSS2 structure following acylation by nafamostat
分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 4-carbamimidamidobenzoic acid, ...
著者Fraser, B.J, Dong, A, Kutera, M, Seitova, A, Li, Y, Hutchinson, A, Edwards, A, Benard, F, Levon, H, Arrowsmith, C.
登録日2023-11-16
公開日2024-01-31
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献High resolution TMPRSS2 structure following acylation by nafamostat
To Be Published

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