8V1F

TMPRSS2 complexed with the noncovalent inhibitor 6-amidino-2-napthol

Summary for 8V1F

• Entry DOI: 10.2210/pdb8v1f/pdb
• Descriptor: Transmembrane protease serine 2 non-catalytic chain, CITRIC ACID, TETRAETHYLENE GLYCOL, ... (12 entities in total)
• Functional Keywords: inhibitor complex, protease, viral entry, structural genomics, structural genomics consortium, sgc, hydrolase, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 84383.08

Authors

Fraser, B.J.,Dong, A.,Kutera, M.,Seitova, A.,Li, Y.,Hutchinson, A.,Edwards, A.,Benard, F.,Halabelian, L.,Arrowsmith, C.,Structural Genomics Consortium (SGC) (deposition date: 2023-11-20, release date: 2024-02-07, Last modification date: 2024-10-30)

• Primary citation: Fraser, B.J.,Dong, A.,Kutera, M.,Seitova, A.,Li, Y.,Hutchinson, A.,Edwards, A.,Benard, F.,Halabelian, L.,Arrowsmith, C.,Structural Genomics Consortium (SGC); TMPRSS2 complexed with the noncovalent inhibitor 6-amidino-2-napthol; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.19 Å)