2V40

Human Adenylosuccinate synthetase isozyme 2 in complex with GDP

Summary for 2V40

DescriptorADENYLOSUCCINATE SYNTHETASE ISOZYME 2, GUANOSINE-5'-DIPHOSPHATE (3 entities in total)
Functional Keywordsligase, purine biosynthesis, adenylosuccinate synthetase, metal- binding, purine metabolism, nucleotide-binding, gdp, adss2, magnesium, gtp-binding
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P30520
Total number of polymer chains1
Total molecular weight51247.06
Authors
Primary citation
Welin, M.,Moche, M.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,van den Berg, S.,Weigelt, J.,Nordlund, P.
Human Adenylosuccinate Synthetase Isozyme 2 in Complex with Gdp
To be Published,
Experimental method
X-RAY DIFFRACTION (1.9 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.199400.3%3.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2v40
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Molmil generated image of 2v40
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Molmil generated image of 2v40
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More Biological unit images

Molmil generated image of 2v40
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Molmil generated image of 2v40
rotated about x axis by 90°
Molmil generated image of 2v40
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2v40.pdb1.gz [157.83 KB])