2UW2

Crystal structure of human ribonucleotide reductase subunit R2

Replaces:  2IYH

Summary for 2UW2

Related2IYH
DescriptorRIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE M2 SUBUNIT, FE (III) ION (3 entities in total)
Functional Keywordssmall subunit ribonucleotide reductase, r2, iron, diiron, radical, r2 subunit, metal-binding, ribonucleotide reductase, oxidoreductase, dna replication, phosphorylation
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm P31350
Total number of polymer chains1
Total molecular weight38749.12
Authors
Primary citation
Welin, M.,Ogg, D.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Edwards, A.,Ehn, M.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg Schiavone, L.,Hogbom, M.,Kotenyova, T.,Magnusdottir, A.,Moche, M.,Nilsson-Ehle, P.,Nyman, T.,Persson, C.,Sagemark, J.,Sundstrom, M.,Stenmark, P.,Uppenberg, J.,Thorsell, A.G.,Van Den Berg, S.,Wallden, K.,Weigelt, J.,Nordlund, P.
Crystal Structure of Human Ribonucleotide Reductase Subunit R2
To be Published,
Experimental method
X-RAY DIFFRACTION (2.8 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.300121.5%7.4%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2uw2
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Molmil generated image of 2uw2
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Molmil generated image of 2uw2
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2uw2
no rotation
Molmil generated image of 2uw2
rotated about x axis by 90°
Molmil generated image of 2uw2
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2uw2.pdb1.gz [92.07 KB])