2UZ9

Human guanine deaminase (guaD) in complex with zinc and its product Xanthine.

Summary for 2UZ9

DescriptorGUANINE DEAMINASE, ZINC ION, XANTHINE, ... (4 entities in total)
Functional Keywordszinc, hydrolase, purine metabolism, guanine aminohydrolase
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains1
Total molecular weight53838.08
Authors
Primary citation
Moche, M.,Welin, M.,Arrowsmith, C.,Berglund, H.,Busam, R.,Collins, R.,Dahlgren, L.G.,Edwards, A.,Flodin, S.,Flores, A.,Graslund, S.,Hammarstrom, M.,Hallberg, B.M.,Holmberg-Schiavone, L.,Johansson, I.,Kallas, A.,Karlberg, T.,Kotenyova, T.,Lehtio, L.,Nyman, T.,Ogg, D.,Persson, C.,Sagemark, J.,Stenmark, P.,Sundstrom, M.,Thorsell, A.G.,Van Den Berg, S.,Weigelt, J.,Nordlund, P.
Human Guanine Deaminase (Guad) in Complex with Zinc and its Product Xhantine
To be Published,
Experimental method
X-RAY DIFFRACTION (2.3 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22140.2%6.6%2.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 2uz9
no rotation
Molmil generated image of 2uz9
rotated about x axis by 90°
Molmil generated image of 2uz9
rotated about y axis by 90°

More Biological unit images

Molmil generated image of 2uz9
no rotation
Molmil generated image of 2uz9
rotated about x axis by 90°
Molmil generated image of 2uz9
rotated about y axis by 90°
(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (2uz9.pdb1.gz [151.02 KB])