Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 98 件
4H8I
DownloadVisualize
BU of 4h8i by Molmil
Structure of GluK2-LBD in complex with GluAzo
分子名称: (4R)-4-[(2E)-3-{4-[(E)-phenyldiazenyl]phenyl}prop-2-en-1-yl]-L-glutamic acid, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, ...
著者Reiter, A, Skerra, A, Trauner, D, Schiefner, A.
登録日2012-09-22
公開日2013-09-25
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A photoswitchable neurotransmitter analogue bound to its receptor.
Biochemistry, 52, 2013
4GRX
DownloadVisualize
BU of 4grx by Molmil
Structure of an omega-aminotransferase from Paracoccus denitrificans
分子名称: Aminotransferase, DELTA-AMINO VALERIC ACID, SODIUM ION
著者Rausch, C, Lerchner, A, Schiefner, A, Skerra, A.
登録日2012-08-27
公開日2012-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of the omega-aminotransferase from Paracoccus denitrificans and its phylogenetic relationship with other class III aminotransferases that have biotechnological potential.
Proteins, 81, 2013
3DDY
DownloadVisualize
BU of 3ddy by Molmil
Structure of lumazine protein, an optical transponder of luminescent bacteria
分子名称: Lumazine protein, RIBOFLAVIN
著者Chatwell, L, Illarionova, V, Illarionov, B, Skerra, A, Bacher, A, Fischer, M.
登録日2008-06-07
公開日2008-07-01
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of lumazine protein, an optical transponder of luminescent bacteria.
J.Mol.Biol., 382, 2008
4GH7
DownloadVisualize
BU of 4gh7 by Molmil
Crystal structure of Anticalin N7A in complex with oncofetal fibronectin fragment Fn7B8
分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Gebauer, M, Skerra, A.
登録日2012-08-07
公開日2012-12-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Combinatorial design of an Anticalin directed against the extra-domain b for the specific targeting of oncofetal fibronectin
J.Mol.Biol., 425, 2013
4MVK
DownloadVisualize
BU of 4mvk by Molmil
Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide fragment VFFAED
分子名称: Amyloid peptide fragment VFFAED, Neutrophil gelatinase-associated lipocalin
著者Eichinger, A, Skerra, A.
登録日2013-09-24
公開日2015-08-12
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide.
Biochem.J., 473, 2016
1XKI
DownloadVisualize
BU of 1xki by Molmil
Crystal structure of human tear lipocalin/von Ebners gland protein
分子名称: CHLORIDE ION, Von Ebner's gland protein, ZINC ION
著者Breustedt, D.A, Korndoerfer, I.P, Redl, B, Skerra, A.
登録日2004-09-29
公開日2004-10-19
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.8-A crystal structure of human tear lipocalin reveals an extended branched cavity with capacity for multiple ligands
J.Biol.Chem., 280, 2005
1XK4
DownloadVisualize
BU of 1xk4 by Molmil
Crystal structure of human calprotectin(S100A8/S100A9)
分子名称: CALCIUM ION, CHLORIDE ION, CITRATE ANION, ...
著者Korndoerfer, I.P, Brueckner, F, Skerra, A.
登録日2004-09-26
公開日2005-10-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The crystal structure of the human (S100A8/S100A9)2 heterotetramer, calprotectin, illustrates how conformational changes of interacting alpha-helices can determine specific association of two EF-hand proteins
J.Mol.Biol., 370, 2007
4MVL
DownloadVisualize
BU of 4mvl by Molmil
Crystal structure of an engineered lipocalin (Anticalin H1GA) in complex with the Alzheimer amyloid peptide Abeta1-40
分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin
著者Eichinger, A, Skerra, A.
登録日2013-09-24
公開日2015-08-12
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide.
Biochem.J., 473, 2016
4HH8
DownloadVisualize
BU of 4hh8 by Molmil
Crystal structure of bovine butyrophilin
分子名称: Butyrophilin subfamily 1 member A1
著者Eichinger, A, Skerra, A.
登録日2012-10-09
公開日2013-11-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The extracellular region of bovine butyrophilin exhibits high structural similarity to human myelin oligodendrocyte glycoprotein
To be Published
4MVI
DownloadVisualize
BU of 4mvi by Molmil
Crystal structure of an engineered lipocalin (Anticalin US7) in complex with the Alzheimer amyloid peptide Abeta(1-40)
分子名称: Beta-amyloid protein 40, Neutrophil gelatinase-associated lipocalin
著者Eichinger, A, Skerra, A.
登録日2013-09-24
公開日2015-08-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献High-affinity Anticalins with aggregation-blocking activity directed against the Alzheimer beta-amyloid peptide.
Biochem.J., 473, 2016
6S8V
DownloadVisualize
BU of 6s8v by Molmil
Structure of the high affinity Anticalin P3D11 in complex with the human CD98 heavy chain ectodomain
分子名称: 1,2-ETHANEDIOL, 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Deuschle, F.-C, Skerra, A.
登録日2019-07-10
公開日2020-03-04
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Development of a high affinity Anticalin®directed against human CD98hc for theranostic applications.
Theranostics, 10, 2020
6SUA
DownloadVisualize
BU of 6sua by Molmil
Structure of the high affinity engineered lipocalin C1B12 in complex with the mouse CD98 heavy chain ectodomain
分子名称: 4F2 cell-surface antigen heavy chain, Neutrophil gelatinase-associated lipocalin, SULFATE ION
著者Schiefner, A, Deuschle, F.-C, Skerra, A.
登録日2019-09-13
公開日2020-06-17
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Design of a surrogate Anticalin protein directed against CD98hc for preclinical studies in mice.
Protein Sci., 29, 2020
3DSZ
DownloadVisualize
BU of 3dsz by Molmil
Engineered human lipocalin 2 in complex with Y-DTPA
分子名称: N-{(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl}-N-{(2R)-2-[bis(carboxymethyl)amino]-3-[4-({[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]carbamothioyl}amino)phenyl]propyl}glycine, YTTRIUM (III) ION, engineered human lipocalin 2
著者Eichinger, A, Skerra, A.
登録日2008-07-14
公開日2009-05-19
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2
J.Am.Chem.Soc., 131, 2009
3DTQ
DownloadVisualize
BU of 3dtq by Molmil
Engineered human lipocalin 2 with specificity for Y-DTPA, apo-form
分子名称: Neutrophil gelatinase-associated lipocalin
著者Eichinger, A, Skerra, A.
登録日2008-07-15
公開日2009-05-12
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献High-affinity recognition of lanthanide(III) chelate complexes by a reprogrammed human lipocalin 2.
J.Am.Chem.Soc., 131, 2009
4QAE
DownloadVisualize
BU of 4qae by Molmil
Crystal structure of an engineered lipocalin (Anticalin) in complex with human hepcidin
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CHLORIDE ION, Hepcidin, ...
著者Giese, T, Skerra, A.
登録日2014-05-04
公開日2015-05-06
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of a hepcidin-binding anticalin in complex with its peptide ligand
To be Published
3BX8
DownloadVisualize
BU of 3bx8 by Molmil
Engineered Human Lipocalin 2 (LCN2), apo-form
分子名称: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, ENGINEERED HUMAN LIPOCALIN 2, PENTAETHYLENE GLYCOL
著者Schonfeld, D.L, Chatwell, L, Skerra, A.
登録日2008-01-11
公開日2009-01-20
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献High affinity molecular recognition and functional blockade of CTLA-4 by an engineered human lipocalin
To be Published
3BX7
DownloadVisualize
BU of 3bx7 by Molmil
Engineered Human Lipocalin 2 (LCN2) in Complex with the Extracellular Domain of Human CTLA-4
分子名称: CYTOTOXIC T-LYMPHOCYTE-ASSOCIATED ANTIGEN 4, ENGINEERED HUMAN LIPOCALIN 2
著者Schonfeld, D.L, Chatwell, L, Skerra, A.
登録日2008-01-11
公開日2009-01-20
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献High affinity molecular recognition and functional blockade of CTLA-4 by an engineered human lipocalin
To be Published
1PKO
DownloadVisualize
BU of 1pko by Molmil
Myelin Oligodendrocyte Glycoprotein (MOG)
分子名称: Myelin Oligodendrocyte Glycoprotein
著者Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U.
登録日2003-06-06
公開日2003-07-15
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (1.45 Å)
主引用文献Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein
Proc.Natl.Acad.Sci.USA, 100, 2003
1KL5
DownloadVisualize
BU of 1kl5 by Molmil
an engineered streptavidin with improved affinity for the strep-tag II peptide : SAm2-StrepII
分子名称: strep-tag II, streptavidin
著者Korndoerfer, I.P, Skerra, A.
登録日2001-12-11
公開日2002-04-03
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Improved affinity of engineered streptavidin for the Strep-tag II peptide is due to a fixed open conformation of the lid-like loop at the binding site.
Protein Sci., 11, 2002
3QKG
DownloadVisualize
BU of 3qkg by Molmil
Crystal structure of alpha-1-microglobulin at 2.3 A resolution
分子名称: GLYCEROL, NICKEL (II) ION, Protein AMBP
著者Meining, W, Skerra, A.
登録日2011-02-01
公開日2012-02-08
最終更新日2024-11-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The crystal structure of human alpha(1)-microglobulin reveals a potential haem-binding site.
Biochem.J., 445, 2012
4QAF
DownloadVisualize
BU of 4qaf by Molmil
Crystal structure of an engineered lipocalin (Anticalin) in complex with VEGF(8-109)
分子名称: 10-{(1R,2R)-2-[(2E)-hex-2-en-1-yl]cyclopropyl}decanoic acid, ACETATE ION, Lipocalin-1, ...
著者Giese, T, Skerra, A.
登録日2014-05-04
公開日2015-05-06
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of an Anticalin with specific blocking activity towards human vascular endothelial growth factor (VEGF) reveals plasticity of the lipocalin fold
To be Published
1PKQ
DownloadVisualize
BU of 1pkq by Molmil
Myelin Oligodendrocyte Glycoprotein-(8-18C5) Fab-complex
分子名称: (8-18C5) chimeric Fab, heavy chain, light chain, ...
著者Breithaupt, C, Schubart, A, Zander, H, Skerra, A, Huber, R, Linington, C, Jacob, U.
登録日2003-06-06
公開日2003-07-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into the antigenicity of myelin oligodendrocyte glycoprotein
Proc.Natl.Acad.Sci.USA, 100, 2003
5N48
DownloadVisualize
BU of 5n48 by Molmil
Structure of Anticalin N9B in complex with extra-domain B of human oncofetal fibronectin
分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Skerra, A.
登録日2017-02-10
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen.
Structure, 26, 2018
5N47
DownloadVisualize
BU of 5n47 by Molmil
Structure of Anticalin N7E in complex with the three-domain fragment Fn7B8 of human oncofetal fibronectin
分子名称: Fibronectin, Neutrophil gelatinase-associated lipocalin
著者Schiefner, A, Skerra, A.
登録日2017-02-10
公開日2018-02-14
最終更新日2024-10-23
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Anticalins Reveal High Plasticity in the Mode of Complex Formation with a Common Tumor Antigen.
Structure, 26, 2018
5N5V
DownloadVisualize
BU of 5n5v by Molmil
Structure of p-boronophenylalanyl tRNA synthetase - apo form
分子名称: CHLORIDE ION, Tyrosine--tRNA ligase
著者Schiefner, A, Skerra, A.
登録日2017-02-14
公開日2018-02-14
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural Basis for the Specific Cotranslational Incorporation of p-Boronophenylalanine into Biosynthetic Proteins.
Biochemistry, 57, 2018

227111

件を2024-11-06に公開中

PDB statisticsPDBj update infoContact PDBjnumon