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PDB: 1889 results

3F4M
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Crystal structure of TIPE2
Descriptor: CHLORIDE ION, Tumor necrosis factor, alpha-induced protein 8-like protein 2
Authors:Zhang, X, Wang, J, Shi, Y.
Deposit date:2008-11-01
Release date:2009-03-17
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (1.696 Å)
Cite:Crystal structure of TIPE2 provides insights into immune homeostasis
Nat.Struct.Mol.Biol., 16, 2009
4M69
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BU of 4m69 by Molmil
Crystal structure of the mouse RIP3-MLKL complex
Descriptor: CHLORIDE ION, MAGNESIUM ION, Mixed lineage kinase domain-like protein, ...
Authors:Xie, T, Peng, W, Yan, C, Wu, J, Shi, Y.
Deposit date:2013-08-09
Release date:2013-10-16
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.497 Å)
Cite:Structural Insights into RIP3-Mediated Necroptotic Signaling
Cell Rep, 5, 2013
8Y6P
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BU of 8y6p by Molmil
Structure of the auto-inhibited Dark monomer
Descriptor: Apaf-1 related killer DARK
Authors:Tian, L, Li, Y, Shi, Y.
Deposit date:2024-02-03
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Dark and Dronc activation in Drosophila melanogaster.
Proc.Natl.Acad.Sci.USA, 121, 2024
1DU9
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BU of 1du9 by Molmil
SOLUTION STRUCTURE OF BMP02, A NATURAL SCORPION TOXIN WHICH BLOCKS APAMIN-SENSITIVE CALCIUM-ACTIVATED POTASSIUM CHANNELS, 25 STRUCTURES
Descriptor: BMP02 NEUROTOXIN
Authors:Xu, Y, Wu, J, Pei, J, Shi, Y, Ji, Y, Tong, Q.
Deposit date:2000-01-17
Release date:2000-02-04
Last modified:2022-02-16
Method:SOLUTION NMR
Cite:Solution structure of BmP02, a new potassium channel blocker from the venom of the Chinese scorpion Buthus martensi Karsch.
Biochemistry, 39, 2000
8X54
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BU of 8x54 by Molmil
Cryo-EM structure of human gamma-secretase in complex with APP-C99
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y.
Deposit date:2023-11-16
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
8X52
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BU of 8x52 by Molmil
Cryo-EM structure of human gamma-secretase in complex with Abeta49
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y.
Deposit date:2023-11-16
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
8X53
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BU of 8x53 by Molmil
Cryo-EM structure of human gamma-secretase in complex with Abeta46
Descriptor: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Guo, X, Yan, C, Lei, J, Zhou, R, Shi, Y.
Deposit date:2023-11-16
Release date:2024-05-29
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3 Å)
Cite:Molecular mechanism of substrate recognition and cleavage by human gamma-secretase.
Science, 384, 2024
7EVN
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BU of 7evn by Molmil
The cryo-EM structure of the DDX42-SF3b complex
Descriptor: ATP-dependent RNA helicase DDX42, PHD finger-like domain-containing protein 5A, Splicing factor 3B subunit 1, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-05-21
Release date:2022-08-03
Last modified:2024-01-17
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structural insights into branch site proofreading by human spliceosome
Nat.Struct.Mol.Biol., 2024
7EVO
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BU of 7evo by Molmil
The cryo-EM structure of the human 17S U2 snRNP
Descriptor: HIV Tat-specific factor 1, PHD finger-like domain-containing protein 5A, RNA helicase, ...
Authors:Zhang, X, Zhan, X, Shi, Y.
Deposit date:2021-05-21
Release date:2022-08-03
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.5 Å)
Cite:Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
8Y7E
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BU of 8y7e by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part
Descriptor: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
Authors:Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
Deposit date:2024-02-04
Release date:2024-03-13
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.66 Å)
Cite:Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
8Y6O
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BU of 8y6o by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U11 and tri-snRNP part
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Centrosomal AT-AC splicing factor, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
Deposit date:2024-02-02
Release date:2024-03-20
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
8BQW
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BU of 8bqw by Molmil
Cryo-EM structure of alpha-synuclein filaments doublet from Juvenile-onset synucleinopathy
Descriptor: Alpha-synuclein, Unknown protein
Authors:Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
Deposit date:2023-01-18
Release date:2023-02-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (2.3 Å)
Cite:New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
8BQV
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BU of 8bqv by Molmil
Cryo-EM structure of alpha-synuclein singlet filament from Juvenile-onset synucleinopathy
Descriptor: Alpha-synuclein, Unknown protein
Authors:Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
Deposit date:2023-01-18
Release date:2023-02-22
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (2 Å)
Cite:New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
8CE7
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BU of 8ce7 by Molmil
Type1 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
Descriptor: Alpha-synuclein
Authors:Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Peak-Chew, S.Y, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
Deposit date:2023-02-01
Release date:2023-03-01
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
8CEB
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BU of 8ceb by Molmil
Type2 alpha-synuclein filament assembled in vitro by wild-type and mutant (7 residues insertion) protein
Descriptor: Alpha-synuclein
Authors:Yang, Y, Garringer, J.H, Shi, Y, Lovestam, S, Sew, P.C, Zhang, X.J, Kotecha, A, Bacioglu, M, Koto, A, Takao, M, Spillantini, G.M, Ghetti, B, Vidal, R, Murzin, G.A, Scheres, H.W.S, Goedert, M.
Deposit date:2023-02-01
Release date:2023-03-08
Last modified:2023-05-03
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:New SNCA mutation and structures of alpha-synuclein filaments from juvenile-onset synucleinopathy.
Acta Neuropathol, 145, 2023
7EP7
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BU of 7ep7 by Molmil
The complex structure of Gpsm2 and Whirlin
Descriptor: G-protein-signaling modulator 2, Whirlin
Authors:Lin, L, Shi, Y, Wang, C, Zhu, J.
Deposit date:2021-04-26
Release date:2022-05-04
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Promotion of row 1-specific tip complex condensates by Gpsm2-G alpha i provides insights into row identity of the tallest stereocilia.
Sci Adv, 8, 2022
1F0K
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BU of 1f0k by Molmil
THE 1.9 ANGSTROM CRYSTAL STRUCTURE OF E. COLI MURG
Descriptor: SULFATE ION, UDP-N-ACETYLGLUCOSAMINE-N-ACETYLMURAMYL-(PENTAPEPTIDE) PYROPHOSPHORYL-UNDECAPRENOL N-ACETYLGLUCOSAMINE TRANSFERASE
Authors:Ha, S, Walker, D, Shi, Y, Walker, S.
Deposit date:2000-05-16
Release date:2000-07-27
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:The 1.9 A crystal structure of Escherichia coli MurG, a membrane-associated glycosyltransferase involved in peptidoglycan biosynthesis.
Protein Sci., 9, 2000
4QY2
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BU of 4qy2 by Molmil
Structure of H10 from human-infecting H10N8 virus in complex with human receptor analog
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid, hemagglutinin
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.399 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4QY1
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BU of 4qy1 by Molmil
Structure of H10 from human-infecting H10N8 in complex with avian receptor
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Wang, M, Zhang, W, Qi, J, Wang, F, Zhou, J, Bi, Y, Wu, Y, Sun, H, Liu, J, Huang, C, Li, X, Yan, J, Shu, Y, Shi, Y, Gao, G.F.
Deposit date:2014-07-23
Release date:2015-01-28
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.594 Å)
Cite:Structural basis for preferential avian receptor binding by the human-infecting H10N8 avian influenza virus
Nat Commun, 6, 2015
4R8W
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BU of 4r8w by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a neutralizing antibody CT149
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of neutralizing antibody CT149, Hemagglutinin, ...
Authors:Wu, Y, Shi, Y, Qi, J, Gao, G.F.
Deposit date:2014-09-03
Release date:2015-08-26
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.795 Å)
Cite:A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus
Nat Commun, 6, 2015
4R12
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BU of 4r12 by Molmil
Crystal structure of the gamma-secretase component Nicastrin
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ...
Authors:Xie, T, Yan, C, Zhou, R, Zhao, Y, Sun, L, Yang, G, Lu, P, Ma, D, Shi, Y.
Deposit date:2014-08-03
Release date:2014-09-17
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of the gamma-secretase component nicastrin.
Proc.Natl.Acad.Sci.USA, 111, 2014
4UIS
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BU of 4uis by Molmil
The cryoEM structure of human gamma-Secretase complex
Descriptor: GAMMA-SECRETASE, LYSOZYME
Authors:Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
Deposit date:2015-04-03
Release date:2015-06-10
Last modified:2017-08-02
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
6XYO
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BU of 6xyo by Molmil
Multiple system atrophy Type I alpha-synuclein filament
Descriptor: Alpha-synuclein
Authors:Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (2.6 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYP
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BU of 6xyp by Molmil
Multiple system atrophy Type II-1 alpha-synuclein filament
Descriptor: Alpha-synuclein
Authors:Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.29 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020
6XYQ
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BU of 6xyq by Molmil
Multiple system atrophy Type II-2 alpha-synuclein filament
Descriptor: Alpha-synuclein
Authors:Schweighauser, M, Shi, Y, Tarutani, A, Kametani, F, Murzin, A.G, Ghetti, B, Matsubara, T, Tomita, T, Ando, T, Hasegawa, K, Murayama, S, Yoshida, M, Hasegawa, M, Scheres, S.H.W, Goedert, M.
Deposit date:2020-01-30
Release date:2020-02-12
Last modified:2024-05-22
Method:ELECTRON MICROSCOPY (3.09 Å)
Cite:Structures of alpha-synuclein filaments from multiple system atrophy.
Nature, 585, 2020

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