5X5F
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![BU of 5x5f by Molmil](/molmil-images/mine/5x5f) | Prefusion structure of MERS-CoV spike glycoprotein, conformation 2 | 分子名称: | S protein | 著者 | Yuan, Y, Cao, D, Zhang, Y, Ma, J, Qi, J, Wang, Q, Lu, G, Wu, Y, Yan, J, Shi, Y, Zhang, X, Gao, G.F. | 登録日 | 2017-02-15 | 公開日 | 2017-05-03 | 最終更新日 | 2017-05-24 | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | 主引用文献 | Cryo-EM structures of MERS-CoV and SARS-CoV spike glycoproteins reveal the dynamic receptor binding domains Nat Commun, 8, 2017
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5VRT
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![BU of 5vrt by Molmil](/molmil-images/mine/5vrt) | Nonheme Iron Replacement in a Biosynthetic Nitric Oxide Reductase Model Performing O2 Reduction to Water: Co-bound FeBMb | 分子名称: | COBALT (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Reed, J, Shi, Y, Zhu, Q, Chakraborty, S, Mirs, E.N, Petrik, I.D, Bhagi-Damodaran, A, Ross, M, Moenne-Loccoz, P, Zhang, Y, Lu, Y. | 登録日 | 2017-05-11 | 公開日 | 2017-08-16 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (1.995 Å) | 主引用文献 | Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism. J. Am. Chem. Soc., 139, 2017
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5Z58
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![BU of 5z58 by Molmil](/molmil-images/mine/5z58) | Cryo-EM structure of a human activated spliceosome (early Bact) at 4.9 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (4.9 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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6KL9
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![BU of 6kl9 by Molmil](/molmil-images/mine/6kl9) | Structure of LbCas12a-crRNA complex bound to AcrVA4 (form A complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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1K88
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![BU of 1k88 by Molmil](/molmil-images/mine/1k88) | Crystal structure of procaspase-7 | 分子名称: | procaspase-7 | 著者 | Chai, J, Wu, Q, Shiozaki, E, Srinivasa, S.M, Alnemri, E.S, Shi, Y. | 登録日 | 2001-10-23 | 公開日 | 2001-11-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding Cell(Cambridge,Mass.), 107, 2001
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4DNW
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![BU of 4dnw by Molmil](/molmil-images/mine/4dnw) | Crystal structure of UVB-resistance protein UVR8 | 分子名称: | AT5g63860/MGI19_6 | 著者 | Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Wang, J, Shi, Y. | 登録日 | 2012-02-09 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.773 Å) | 主引用文献 | Structural basis of ultraviolet-B perception by UVR8. Nature, 484, 2012
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6KLB
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![BU of 6klb by Molmil](/molmil-images/mine/6klb) | Structure of LbCas12a-crRNA complex bound to AcrVA4 (form B complex) | 分子名称: | AcrVA4, LbCas12a, MAGNESIUM ION, ... | 著者 | Peng, R, Li, Z, Xu, Y, He, S, Peng, Q, Shi, Y, Gao, G.F. | 登録日 | 2019-07-30 | 公開日 | 2019-09-11 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Structural insight into multistage inhibition of CRISPR-Cas12a by AcrVA4. Proc.Natl.Acad.Sci.USA, 116, 2019
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5ZWO
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![BU of 5zwo by Molmil](/molmil-images/mine/5zwo) | Cryo-EM structure of the yeast B complex at average resolution of 3.9 angstrom | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 23 kDa U4/U6.U5 small nuclear ribonucleoprotein component, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, ... | 著者 | Bai, R, Wan, R, Yan, C, Shi, Y. | 登録日 | 2018-05-16 | 公開日 | 2018-08-29 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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5WVE
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![BU of 5wve by Molmil](/molmil-images/mine/5wve) | Apaf-1-Caspase-9 holoenzyme | 分子名称: | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, Apoptotic protease-activating factor 1, Caspase, ... | 著者 | Li, Y, Zhou, M, Hu, Q, Shi, Y. | 登録日 | 2016-12-24 | 公開日 | 2017-02-08 | 最終更新日 | 2017-03-01 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Mechanistic insights into caspase-9 activation by the structure of the apoptosome holoenzyme Proc. Natl. Acad. Sci. U.S.A., 114, 2017
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5ZWM
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![BU of 5zwm by Molmil](/molmil-images/mine/5zwm) | Cryo-EM structure of the yeast pre-B complex at an average resolution of 3.4~4.6 angstrom (tri-snRNP and U2 snRNP Part) | 分子名称: | 13 kDa ribonucleoprotein-associated protein, 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Cold sensitive U2 snRNA suppressor 1, ... | 著者 | Bai, R, Wan, R, Yan, C, Lei, J, Shi, Y. | 登録日 | 2018-05-16 | 公開日 | 2018-08-29 | 最終更新日 | 2019-11-06 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structures of the fully assembledSaccharomyces cerevisiaespliceosome before activation Science, 360, 2018
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4DNV
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![BU of 4dnv by Molmil](/molmil-images/mine/4dnv) | Crystal structure of the W285F mutant of UVB-resistance protein UVR8 | 分子名称: | AT5g63860/MGI19_6 | 著者 | Wu, D, Hu, Q, Yan, Z, Chen, W, Yan, C, Zhang, J, Wang, J, Shi, Y. | 登録日 | 2012-02-09 | 公開日 | 2012-03-07 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Structural basis of ultraviolet-B perception by UVR8. Nature, 484, 2012
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6AHD
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![BU of 6ahd by Molmil](/molmil-images/mine/6ahd) | The Cryo-EM Structure of Human Pre-catalytic Spliceosome (B complex) at 3.8 angstrom resolution | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, Brr2, U5 small nuclear ribonucleoprotein 200 kDa helicase, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | 登録日 | 2018-08-17 | 公開日 | 2018-11-14 | 最終更新日 | 2021-06-30 | 実験手法 | ELECTRON MICROSCOPY (3.8 Å) | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
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6KUJ
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![BU of 6kuj by Molmil](/molmil-images/mine/6kuj) | Structure of influenza D virus polymerase bound to cRNA promoter in class 1 | 分子名称: | 3'-cRNA promoter, 5'-cRNA promoter, Polymerase 3, ... | 著者 | Peng, Q, Peng, R, Qi, J, Gao, G.F, Shi, Y. | 登録日 | 2019-09-02 | 公開日 | 2019-10-02 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure of influenza D virus polymerase bound to cRNA promoter in Mode A conformation NAT NANOTECHNOL, 2019
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4F23
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![BU of 4f23 by Molmil](/molmil-images/mine/4f23) | Influenza A virus hemagglutinin H16 HA0 structure with an alpha-helix conformation in the cleavage site: a potential drug target | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin | 著者 | Lu, X, Shi, Y, Gao, F, Xiao, H, Qi, J, Gao, G.F. | 登録日 | 2012-05-07 | 公開日 | 2012-11-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage. J.Virol., 86, 2012
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2AR9
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![BU of 2ar9 by Molmil](/molmil-images/mine/2ar9) | Crystal structure of a dimeric caspase-9 | 分子名称: | Caspase-9, D-MALATE | 著者 | Chao, Y, Shiozaki, E.N, Srinivassula, S.M, Rigotti, D.J, Fairman, R, Shi, Y. | 登録日 | 2005-08-19 | 公開日 | 2005-10-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Engineering a Dimeric Caspase-9: A Re-Evaluation of the Induced Proximity Model for Caspase Activation PLOS BIOL., 3, 2005
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5Z56
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![BU of 5z56 by Molmil](/molmil-images/mine/5z56) | cryo-EM structure of a human activated spliceosome (mature Bact) at 5.1 angstrom. | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (5.1 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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1K86
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![BU of 1k86 by Molmil](/molmil-images/mine/1k86) | Crystal structure of caspase-7 | 分子名称: | caspase-7 | 著者 | Chai, J, Wu, Q, Shiozaki, E, Srinivasa, S.M, Alnemri, E.S, Shi, Y. | 登録日 | 2001-10-23 | 公開日 | 2001-11-21 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Crystal structure of a procaspase-7 zymogen: mechanisms of activation and substrate binding Cell(Cambridge,Mass.), 107, 2001
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5Z57
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![BU of 5z57 by Molmil](/molmil-images/mine/5z57) | Cryo-EM structure of the human activated spliceosome (late Bact) at 6.5 angstrom | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, ALANINE, BUD13 homolog, ... | 著者 | Zhang, X, Yan, C, Zhan, X, Li, L, Lei, J, Shi, Y. | 登録日 | 2018-01-17 | 公開日 | 2018-09-19 | 最終更新日 | 2020-10-14 | 実験手法 | ELECTRON MICROSCOPY (6.5 Å) | 主引用文献 | Structure of the human activated spliceosome in three conformational states. Cell Res., 28, 2018
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5VNU
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![BU of 5vnu by Molmil](/molmil-images/mine/5vnu) | Nonheme Iron Replacement in a Biosynthetic Nitric Oxide Reductase Model Performing O2 Reduction to Water: Mn-bound FeBMb | 分子名称: | MANGANESE (II) ION, Myoglobin, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Reed, J, Shi, Y, Zhu, Q, Chakraborty, S, Mirs, E.N, Petrik, I.D, Bhagi-Damodaran, A, Ross, M, Moenne-Loccoz, P, Zhang, Y, Lu, Y. | 登録日 | 2017-05-01 | 公開日 | 2017-08-16 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (1.584 Å) | 主引用文献 | Manganese and Cobalt in the Nonheme-Metal-Binding Site of a Biosynthetic Model of Heme-Copper Oxidase Superfamily Confer Oxidase Activity through Redox-Inactive Mechanism. J. Am. Chem. Soc., 139, 2017
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4FIU
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![BU of 4fiu by Molmil](/molmil-images/mine/4fiu) | The structure of hemagglutinin of H16 subtype influenza virus with V327G mutation | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, hemagglutinin | 著者 | Lu, X, Shi, Y, Gao, F, Xiao, H, Wang, M, Qi, J, Gao, G.F. | 登録日 | 2012-06-11 | 公開日 | 2012-11-21 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.999 Å) | 主引用文献 | Insights into Avian Influenza Virus Pathogenicity: the Hemagglutinin Precursor HA0 of Subtype H16 Has an Alpha-Helix Structure in Its Cleavage Site with Inefficient HA1/HA2 Cleavage. J.Virol., 86, 2012
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6AH0
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![BU of 6ah0 by Molmil](/molmil-images/mine/6ah0) | The Cryo-EM Structure of the Precusor of Human Pre-catalytic Spliceosome (pre-B complex) | 分子名称: | 116 kDa U5 small nuclear ribonucleoprotein component, GUANOSINE-5'-TRIPHOSPHATE, INOSITOL HEXAKISPHOSPHATE, ... | 著者 | Zhan, X, Yan, C, Zhang, X, Shi, Y. | 登録日 | 2018-08-15 | 公開日 | 2018-11-14 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (5.7 Å) | 主引用文献 | Structures of the human pre-catalytic spliceosome and its precursor spliceosome. Cell Res., 28, 2018
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4GNE
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![BU of 4gne by Molmil](/molmil-images/mine/4gne) | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-7 | 分子名称: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | 著者 | Li, F, He, C, Wu, J, Shi, Y. | 登録日 | 2012-08-17 | 公開日 | 2013-01-02 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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4GND
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![BU of 4gnd by Molmil](/molmil-images/mine/4gnd) | Crystal Structure of NSD3 tandem PHD5-C5HCH domains | 分子名称: | Histone-lysine N-methyltransferase NSD3, ZINC ION | 著者 | Li, F, He, C, Wu, J, Shi, Y. | 登録日 | 2012-08-17 | 公開日 | 2013-01-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.27 Å) | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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4GNG
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![BU of 4gng by Molmil](/molmil-images/mine/4gng) | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3K9me3 peptide | 分子名称: | GLYCEROL, Histone H3.3, Histone-lysine N-methyltransferase NSD3, ... | 著者 | Li, F, He, C, Wu, J, Shi, Y. | 登録日 | 2012-08-17 | 公開日 | 2013-01-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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4GNF
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![BU of 4gnf by Molmil](/molmil-images/mine/4gnf) | Crystal Structure of NSD3 tandem PHD5-C5HCH domains complexed with H3 peptide 1-15 | 分子名称: | Histone H3.3, Histone-lysine N-methyltransferase NSD3, ZINC ION | 著者 | Li, F, He, C, Wu, J, Shi, Y. | 登録日 | 2012-08-17 | 公開日 | 2013-01-02 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | 主引用文献 | The methyltransferase NSD3 has chromatin-binding motifs, PHD5-C5HCH, that are distinct from other NSD (nuclear receptor SET domain) family members in their histone H3 recognition. J.Biol.Chem., 288, 2013
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