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PDB: 1959 件

4QVD
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BU of 4qvd by Molmil
E.coli Hfq in complex with RNA Ads
分子名称: RNA (5'-R(*AP*AP*CP*UP*AP*AP*A)-3'), RNA-binding protein Hfq
著者Wang, L.J, Wang, W.W, Li, F.D, Wu, J.H, Gong, Q.G, Shi, Y.Y.
登録日2014-07-14
公開日2015-05-27
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.972 Å)
主引用文献Structural insights into the recognition of the internal A-rich linker from OxyS sRNA by Escherichia coli Hfq
Nucleic Acids Res., 43, 2015
4UIS
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BU of 4uis by Molmil
The cryoEM structure of human gamma-Secretase complex
分子名称: GAMMA-SECRETASE, LYSOZYME
著者Sun, L, Zhao, L, Yang, G, Yan, C, Zhou, R, Zhou, X, Xie, T, Zhao, Y, Wu, S, Li, X, Shi, Y.
登録日2015-04-03
公開日2015-06-10
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Structural Basis of Human Gamma-Secretase Assembly.
Proc.Natl.Acad.Sci.USA, 112, 2015
8Y7E
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BU of 8y7e by Molmil
Cryo-EM Structure of the human minor pre-B complex (pre-precatalytic spliceosome) U12 snRNP part
分子名称: PHD finger-like domain-containing protein 5A, Small nuclear ribonucleoprotein E, Small nuclear ribonucleoprotein F, ...
著者Bai, R, Yuan, M, Zhang, P, Luo, T, Shi, Y, Wan, R.
登録日2024-02-04
公開日2024-03-13
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.66 Å)
主引用文献Structural basis of U12-type intron engagement by the fully assembled human minor spliceosome.
Science, 383, 2024
6II4
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BU of 6ii4 by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4A-14
分子名称: Heavy chain of L4A-14 Fab, Hemagglutinin, Light chain of L4A-14 Fab
著者Jiang, H.H, Shi, Y, Qi, J, Gao, G.F.
登録日2018-10-03
公開日2018-10-24
最終更新日2019-02-06
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019
5DNP
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BU of 5dnp by Molmil
Crystal structure of Mmi1 YTH domain
分子名称: PHOSPHATE ION, YTH domain-containing protein mmi1
著者Wang, C.Y, Zhu, Y.W, Shi, Y.Y, Wu, J.H.
登録日2015-09-10
公開日2016-04-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1
Nucleic Acids Res., 44, 2016
5DNO
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BU of 5dno by Molmil
Crystal structure of Mmi1 YTH domain complex with RNA
分子名称: RNA (5'-R(*CP*UP*UP*AP*AP*AP*C)-3'), YTH domain-containing protein mmi1
著者Wang, C.Y, Zhu, Y.W, Wu, J.H, Shi, Y.Y.
登録日2015-09-10
公開日2016-04-06
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1
Nucleic Acids Res., 44, 2016
6II9
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BU of 6ii9 by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L3A-44
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L3A-44 Fab, Hemagglutinin, ...
著者Jiang, H.H, Shi, Y, Qi, J, Gao, G.F.
登録日2018-10-03
公開日2018-10-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019
6II8
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BU of 6ii8 by Molmil
Crystal structure of H7 hemagglutinin from A/Anhui/1/2013 in complex with a human neutralizing antibody L4B-18
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain of L4B-18 Fab, Hemagglutinin, ...
著者Jiang, H.H, Shi, Y, Qi, J, Gao, G.F.
登録日2018-10-03
公開日2018-10-24
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (3.32 Å)
主引用文献Structure-function analysis of neutralizing antibodies to H7N9 influenza from naturally infected humans.
Nat Microbiol, 4, 2019
4R7A
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BU of 4r7a by Molmil
Crystal Structure of RBBP4 bound to PHF6 peptide
分子名称: GLYCEROL, Histone-binding protein RBBP4, PHD finger protein 6
著者Liu, Z, Li, F, Zhang, B, Li, S, Wu, J, Shi, Y.
登録日2014-08-27
公開日2015-01-14
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis of Plant Homeodomain Finger 6 (PHF6) Recognition by the Retinoblastoma Binding Protein 4 (RBBP4) Component of the Nucleosome Remodeling and Deacetylase (NuRD) Complex
J.Biol.Chem., 290, 2015
4RHW
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BU of 4rhw by Molmil
Crystal structure of Apaf-1 CARD and caspase-9 CARD complex
分子名称: Apoptotic protease-activating factor 1, CHLORIDE ION, Caspase-9, ...
著者Hu, Q, Wu, D, Yan, C, Shi, Y.
登録日2014-10-03
公開日2014-10-15
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome.
Proc. Natl. Acad. Sci. U.S.A., 111, 2014
8JKT
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BU of 8jkt by Molmil
Crystal structure of feline aminopeptidase N ectodomain
分子名称: Aminopeptidase N
著者Tan, Y.B, Shi, Y.J, Peng, G.Q.
登録日2023-06-01
公開日2024-06-05
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of feline aminopeptidase N ectodomain
To Be Published
8E9E
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BU of 8e9e by Molmil
Rat protein farnesyltransferase in complex with FPP and inhibitor 2f
分子名称: (5S)-4-({1-[(4-bromophenyl)methyl]-1H-imidazol-5-yl}methyl)-5-butyl-1-[3-(trifluoromethoxy)phenyl]piperazin-2-one, 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ...
著者Wang, Y, Shi, Y, Beese, L.S.
登録日2022-08-26
公開日2022-10-26
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.844 Å)
主引用文献Structure-Guided Discovery of Potent Antifungals that Prevent Ras Signaling by Inhibiting Protein Farnesyltransferase.
J.Med.Chem., 65, 2022
6IEX
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BU of 6iex by Molmil
Crystal structure of HLA-B*4001 in complex with SARS-CoV derived peptide N216-225 GETALALLLL
分子名称: Beta-2-microglobulin, GLY-GLU-THR-ALA-LEU-ALA-LEU-LEU-LEU-LEU, MHC class I antigen
著者Ji, W, Niu, L, Peng, W, Zhang, Y, Shi, Y, Qi, J, Gao, G.F, Liu, W.J.
登録日2018-09-17
公開日2019-09-18
最終更新日2021-03-31
実験手法X-RAY DIFFRACTION (2.314 Å)
主引用文献Salt bridge-forming residues positioned over viral peptides presented by MHC class I impacts T-cell recognition in a binding-dependent manner.
Mol.Immunol., 112, 2019
7VPX
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BU of 7vpx by Molmil
The cryo-EM structure of the human pre-A complex
分子名称: 5SS, DnaJ homolog subfamily C member 8, PHD finger-like domain-containing protein 5A, ...
著者Zhang, X, Zhan, X, Shi, Y.
登録日2021-10-18
公開日2023-05-03
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Structural insights into branch site proofreading by human spliceosome.
Nat.Struct.Mol.Biol., 2024
6O0W
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BU of 6o0w by Molmil
Crystal structure of the TIR domain from the grapevine disease resistance protein RUN1 in complex with NADP+ and Bis-Tris
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENOSINE-2'-5'-DIPHOSPHATE, TIR-NB-LRR type resistance protein RUN1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0V
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BU of 6o0v by Molmil
Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 2
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.07 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0S
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BU of 6o0s by Molmil
Crystal structure of the tandem SAM domains from human SARM1
分子名称: Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0T
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BU of 6o0t by Molmil
Crystal structure of selenomethionine labelled tandem SAM domains (L446M:L505M:L523M mutant) from human SARM1
分子名称: Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O1B
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BU of 6o1b by Molmil
Crystal structure of the TIR domain G601P mutant from human SARM1, crystal form 1
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-18
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0R
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BU of 6o0r by Molmil
Crystal structure of the TIR domain from human SARM1 in complex with glycerol
分子名称: GLYCEROL, Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0U
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BU of 6o0u by Molmil
Crystal structure of the TIR domain H685A mutant from human SARM1
分子名称: Sterile alpha and TIR motif-containing protein 1
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.03 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
6O0Q
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BU of 6o0q by Molmil
Crystal structure of the TIR domain from human SARM1 in complex with ribose
分子名称: CHLORIDE ION, Sterile alpha and TIR motif-containing protein 1, beta-D-ribofuranose
著者Horsefield, S, Burdett, H, Zhang, X, Manik, M.K, Shi, Y, Chen, J, Tiancong, Q, Gilley, J, Lai, J, Gu, W, Rank, M, Deerain, N, Casey, L, Ericsson, D.J, Foley, G, Hughes, R.O, Bosanac, T, von Itzstein, M, Rathjen, J.P, Nanson, J.D, Boden, M, Dry, I.B, Williams, S.J, Staskawicz, B.J, Coleman, M.P, Ve, T, Dodds, P.N, Kobe, B.
登録日2019-02-17
公開日2019-09-04
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献NAD+cleavage activity by animal and plant TIR domains in cell death pathways.
Science, 365, 2019
5FN3
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BU of 5fn3 by Molmil
Cryo-EM structure of gamma secretase in class 1 of the apo- state ensemble
分子名称: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
著者Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
登録日2015-11-10
公開日2015-12-16
最終更新日2019-09-11
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN2
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BU of 5fn2 by Molmil
Cryo-EM structure of gamma secretase in complex with a drug DAPT
分子名称: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
著者Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
登録日2015-11-10
公開日2015-12-16
最終更新日2019-09-04
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FN4
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BU of 5fn4 by Molmil
Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble
分子名称: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
著者Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
登録日2015-11-10
公開日2015-12-16
最終更新日2019-09-11
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015

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件を2024-06-19に公開中

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