4OCS
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![BU of 4ocs by Molmil](/molmil-images/mine/4ocs) | Crystal structure of human Fab CAP256-VRC26.10, a potent V1V2-directed HIV-1 neutralizing antibody | 分子名称: | CAP256-VRC26.10 heavy chain, CAP256-VRC26.10 light chain | 著者 | Gorman, J, Doria-Rose, N.A, Schramm, C.A, Moore, P.L, Mascola, J.R, Shapiro, L, Morris, L, Kwong, P.D. | 登録日 | 2014-01-09 | 公開日 | 2014-02-26 | 最終更新日 | 2023-12-06 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies. Nature, 509, 2014
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6XEY
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![BU of 6xey by Molmil](/molmil-images/mine/6xey) | Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4 | 分子名称: | 2-4 Heavy Chain, 2-4 Light Chain, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Rapp, M, Shapiro, L, Ho, D.D. | 登録日 | 2020-06-14 | 公開日 | 2020-07-22 | 最終更新日 | 2021-01-27 | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | 主引用文献 | Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. Nature, 584, 2020
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6XF6
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![BU of 6xf6 by Molmil](/molmil-images/mine/6xf6) | Cryo-EM structure of a biotinylated SARS-CoV-2 spike probe in the prefusion state (1 RBD up) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. | 登録日 | 2020-06-15 | 公開日 | 2020-09-02 | 最終更新日 | 2020-12-02 | 実験手法 | ELECTRON MICROSCOPY (4 Å) | 主引用文献 | Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. SSRN, 2020
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6XF5
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![BU of 6xf5 by Molmil](/molmil-images/mine/6xf5) | Cryo-EM structure of a biotinylated SARS-CoV-2 spike probe in the prefusion state (RBDs down) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein | 著者 | Cerutti, G, Gorman, J, Kwong, P.D, Shapiro, L. | 登録日 | 2020-06-15 | 公開日 | 2020-09-02 | 最終更新日 | 2020-12-02 | 実験手法 | ELECTRON MICROSCOPY (3.45 Å) | 主引用文献 | Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. SSRN, 2020
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3BL8
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![BU of 3bl8 by Molmil](/molmil-images/mine/3bl8) | Crystal structure of the extracellular domain of neuroligin 2A from mouse | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Neuroligin-2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Jin, X, Koehnke, J, Shapiro, L. | 登録日 | 2007-12-10 | 公開日 | 2008-02-19 | 最終更新日 | 2021-03-31 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Crystal structure of the extracellular cholinesterase-like domain from neuroligin-2. Proc.Natl.Acad.Sci.Usa, 105, 2008
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3BOD
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![BU of 3bod by Molmil](/molmil-images/mine/3bod) | Structure of mouse beta-neurexin 1 | 分子名称: | CALCIUM ION, Neurexin-1-alpha | 著者 | Koehnke, J, Jin, X, Shapiro, L. | 登録日 | 2007-12-17 | 公開日 | 2008-03-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Crystal Structures of beta-Neurexin 1 and beta-Neurexin 2 Ectodomains and Dynamics of Splice Insertion Sequence 4. Structure, 16, 2008
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3BOP
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![BU of 3bop by Molmil](/molmil-images/mine/3bop) | |
2ESR
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![BU of 2esr by Molmil](/molmil-images/mine/2esr) | conserved hypothetical protein- streptococcus pyogenes | 分子名称: | Methyltransferase, alpha-D-glucopyranose | 著者 | Jiang, J, Min, T, Gorman, J, Shapiro, L, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2005-10-26 | 公開日 | 2006-02-07 | 最終更新日 | 2021-02-03 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal Structure of hypothetical protein of Streptococcus Pygenes To be Published
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2F02
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![BU of 2f02 by Molmil](/molmil-images/mine/2f02) | |
2V0C
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![BU of 2v0c by Molmil](/molmil-images/mine/2v0c) | LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A SULPHAMOYL ANALOGUE OF LEUCYL-ADENYLATE In the synthetic site and an adduct of AMP with 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole (AN2690) in the editing site | 分子名称: | AMINOACYL-TRNA SYNTHETASE, LEUCINE, SULFATE ION, ... | 著者 | Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K. | 登録日 | 2007-05-14 | 公開日 | 2007-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site. Science, 316, 2007
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2V0G
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![BU of 2v0g by Molmil](/molmil-images/mine/2v0g) | LEUCYL-TRNA SYNTHETASE FROM THERMUS THERMOPHILUS COMPLEXED WITH A tRNA(leu) transcript with 5-FLUORO-1,3-DIHYDRO-1-HYDROXY-2,1- BENZOXABOROLE (AN2690) forming an adduct to the ribose of adenosine- 76 in the enzyme editing site. | 分子名称: | AMINOACYL-TRNA SYNTHETASE, LEUCINE, MERCURY (II) ION, ... | 著者 | Rock, F, Mao, W, Yaremchuk, A, Tukalo, M, Crepin, T, Zhou, H, Zhang, Y, Hernandez, V, Akama, T, Baker, S, Plattner, J, Shapiro, L, Martinis, S.A, Benkovic, S.J, Cusack, S, Alley, M.R.K. | 登録日 | 2007-05-14 | 公開日 | 2007-07-03 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | 主引用文献 | An Antifungal Agent Inhibits an Aminoacyl-tRNA Synthetase by Trapping tRNA in the Editing Site. Science, 316, 2007
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2QRC
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![BU of 2qrc by Molmil](/molmil-images/mine/2qrc) | Crystal structure of the adenylate sensor from AMP-activated protein kinase in complex with ADP and AMP | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, Protein C1556.08c, ... | 著者 | Jin, X, Townley, R, Shapiro, L. | 登録日 | 2007-07-28 | 公開日 | 2007-10-23 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structural Insight into AMPK Regulation: ADP Comes into Play. Structure, 15, 2007
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4O6M
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![BU of 4o6m by Molmil](/molmil-images/mine/4o6m) | Structure of AF2299, a CDP-alcohol phosphotransferase (CMP-bound) | 分子名称: | AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ... | 著者 | Clarke, O.B, Sciara, G, Tomasek, D, Banerjee, S, Rajashankar, K.R, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | 登録日 | 2013-12-22 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.901 Å) | 主引用文献 | Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat Commun, 5, 2014
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4O6N
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![BU of 4o6n by Molmil](/molmil-images/mine/4o6n) | Structure of AF2299, a CDP-alcohol phosphotransferase (CDP-bound) | 分子名称: | AF2299, a CDP-alcohol phosphotransferase, CALCIUM ION, ... | 著者 | Clarke, O.B, Sciara, G, Tomasek, D, Banerjee, S, Rajashankar, K.R, Shapiro, L, Mancia, F, New York Consortium on Membrane Protein Structure (NYCOMPS) | 登録日 | 2013-12-22 | 公開日 | 2014-05-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural basis for catalysis in a CDP-alcohol phosphotransferase. Nat Commun, 5, 2014
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4DN6
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7JGZ
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![BU of 7jgz by Molmil](/molmil-images/mine/7jgz) | Protocadherin gammaC4 EC1-4 crystal structure | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. | 登録日 | 2020-07-20 | 公開日 | 2021-07-14 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.51 Å) | 主引用文献 | How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition. Elife, 11, 2022
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7RGF
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![BU of 7rgf by Molmil](/molmil-images/mine/7rgf) | Protocadherin gammaC4 EC1-4 crystal structure disrupted trans interface | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Goodman, K.M, Mannepalli, S, Honig, B, Shapiro, L. | 登録日 | 2021-07-15 | 公開日 | 2022-03-16 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition. Elife, 11, 2022
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7SD5
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![BU of 7sd5 by Molmil](/molmil-images/mine/7sd5) | Crystallographic structure of neutralizing antibody 10-40 in complex with SARS-CoV-2 spike receptor binding domain | 分子名称: | 10-40 Heavy chain, 10-40 Light chain, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Reddem, E.R, Casner, R.G, Shapiro, L. | 登録日 | 2021-09-29 | 公開日 | 2022-04-27 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | 主引用文献 | An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med, 14, 2022
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7SI2
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![BU of 7si2 by Molmil](/molmil-images/mine/7si2) | |
7THK
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![BU of 7thk by Molmil](/molmil-images/mine/7thk) | |
7TTM
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![BU of 7ttm by Molmil](/molmil-images/mine/7ttm) | |
7TTX
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![BU of 7ttx by Molmil](/molmil-images/mine/7ttx) | |
7TTY
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![BU of 7tty by Molmil](/molmil-images/mine/7tty) | |
8EM7
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![BU of 8em7 by Molmil](/molmil-images/mine/8em7) | Cryo-EM structure of LRP2 at pH 5.2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Beenken, A, Cerutti, G, Fitzpatrick, A.W, Barasch, J, Shapiro, L. | 登録日 | 2022-09-27 | 公開日 | 2023-02-08 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.97 Å) | 主引用文献 | Structures of LRP2 reveal a molecular machine for endocytosis. Cell, 186, 2023
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8EM4
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![BU of 8em4 by Molmil](/molmil-images/mine/8em4) | Cryo-EM structure of LRP2 at pH 7.5 | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Beenken, A, Cerutti, G, Brasch, J, Fitzpatrick, A.W, Barasch, J, Shapiro, L. | 登録日 | 2022-09-26 | 公開日 | 2023-02-08 | 最終更新日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structures of LRP2 reveal a molecular machine for endocytosis. Cell, 186, 2023
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