Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-4

Summary for 6XEY

EMDB information22156
DescriptorSARS-CoV-2 spike glycoprotein, 2-4 Heavy Chain, 2-4 Light Chain, ... (7 entities in total)
Functional Keywordsspike, glycoprotein, antibody, viral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceSevere acute respiratory syndrome coronavirus 2 (2019-nCoV)
Total number of polymer chains9
Total molecular weight515994.21
Rapp, M.,Shapiro, L.,Ho, D.D. (deposition date: 2020-06-14, release date: 2020-07-22, Last modification date: 2020-08-12)
Primary citation
Liu, L.,Wang, P.,Nair, M.S.,Yu, J.,Rapp, M.,Wang, Q.,Luo, Y.,Chan, J.F.,Sahi, V.,Figueroa, A.,Guo, X.V.,Cerutti, G.,Bimela, J.,Gorman, J.,Zhou, T.,Chen, Z.,Yuen, K.Y.,Kwong, P.D.,Sodroski, J.G.,Yin, M.T.,Sheng, Z.,Huang, Y.,Shapiro, L.,Ho, D.D.
Potent neutralizing antibodies directed to multiple epitopes on SARS-CoV-2 spike.
Nature, 2020
PubMed: 32698192 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-020-2571-7
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers3 0.1% 0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-08-12