7RGF

Protocadherin gammaC4 EC1-4 crystal structure disrupted trans interface

Summary for 7RGF

• Entry DOI: 10.2210/pdb7rgf/pdb
• Descriptor: Protocadherin gamma C4, beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... (9 entities in total)
• Functional Keywords: cadherin, cell-surface receptor, neuronal self-avoidance, cell adhesion
• Biological source: Mus musculus (Mouse)
• Total number of polymer chains: 2
• Total formula weight: 98921.00

Authors

Goodman, K.M.,Mannepalli, S.,Honig, B.,Shapiro, L. (deposition date: 2021-07-15, release date: 2022-03-16, Last modification date: 2023-10-18)

• Primary citation: Goodman, K.M.,Katsamba, P.S.,Rubinstein, R.,Ahlsen, G.,Bahna, F.,Mannepalli, S.,Dan, H.,Sampogna, R.V.,Shapiro, L.,Honig, B.; How clustered protocadherin binding specificity is tuned for neuronal self-/nonself-recognition.; Elife, 11:-, 2022; PubMed: 35253643; DOI: 10.7554/eLife.72416

Experimental method

X-RAY DIFFRACTION (2.4 Å)