4BKX
| The structure of HDAC1 in complex with the dimeric ELM2-SANT domain of MTA1 from the NuRD complex | Descriptor: | ACETATE ION, HISTONE DEACETYLASE 1, METASTASIS-ASSOCIATED PROTEIN MTA1, ... | Authors: | Millard, C.J, Watson, P.J, Celardo, I, Gordiyenko, Y, Cowley, S.M, Robinson, C.V, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2013-04-30 | Release date: | 2013-07-03 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Class I Hdacs Share a Common Mechanism of Regulation by Inositol Phosphates. Mol.Cell, 51, 2013
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4A69
| Structure of HDAC3 bound to corepressor and inositol tetraphosphate | Descriptor: | ACETATE ION, D-MYO INOSITOL 1,4,5,6 TETRAKISPHOSPHATE, GLYCEROL, ... | Authors: | Watson, P.J, Fairall, L, Santos, G.M, Schwabe, J.W.R. | Deposit date: | 2011-11-01 | Release date: | 2012-01-11 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Structure of Hdac3 Bound to Co-Repressor and Inositol Tetraphosphate. Nature, 481, 2012
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4D6K
| Structure of DNTTIP1 dimerisation domain. | Descriptor: | DEOXYNUCLEOTIDYLTRANSFERASE TERMINAL-INTERACTING PROTEIN 1 | Authors: | Itoh, T, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2014-11-11 | Release date: | 2015-02-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Functional Characterization of a Cell Cycle Associated Hdac1/2 Complex Reveals the Structural Basis for Complex Assembly and Nucleosome Targeting. Nucleic Acids Res., 43, 2015
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2YHO
| The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor | Descriptor: | ACETATE ION, E3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ... | Authors: | Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R. | Deposit date: | 2011-05-04 | Release date: | 2011-06-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor. Genes Dev., 25, 2011
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2VST
| hPPARgamma Ligand binding domain in complex with 13-(S)-HODE | Descriptor: | (9Z,11E,13S)-13-hydroxyoctadeca-9,11-dienoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | Authors: | Itoh, T, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2008-04-29 | Release date: | 2008-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
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2YHN
| The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor | Descriptor: | E3 UBIQUITIN-PROTEIN LIGASE MYLIP, ZINC ION | Authors: | Fairall, L, Goult, B.T, Millard, C.J, Tontonoz, P, Schwabe, J.W.R. | Deposit date: | 2011-05-04 | Release date: | 2011-06-29 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor. Genes Dev., 25, 2011
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2VV3
| hPPARgamma Ligand binding domain in complex with 4-oxoDHA | Descriptor: | (6E,10Z,13Z,16Z,19Z)-4-oxodocosa-6,10,13,16,19-pentaenoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | Authors: | Itoh, T, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2008-06-02 | Release date: | 2008-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Structural Basis for the Activation of Ppargamma by Oxidized Fatty Acids. Nat.Struct.Mol.Biol., 15, 2008
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2VV0
| hPPARgamma Ligand binding domain in complex with DHA | Descriptor: | DOCOSA-4,7,10,13,16,19-HEXAENOIC ACID, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | Authors: | Itoh, T, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2008-06-02 | Release date: | 2008-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
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2XTD
| Structure of the TBL1 tetramerisation domain | Descriptor: | TBL1 F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X | Authors: | Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R. | Deposit date: | 2010-10-06 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.2 Å) | Cite: | Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery. Nat.Struct.Mol.Biol., 18, 2011
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2VV2
| hPPARgamma Ligand binding domain in complex with 5-HEPA | Descriptor: | (5R,6E,8Z,11Z,14Z,17Z)-5-hydroxyicosa-6,8,11,14,17-pentaenoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | Authors: | Itoh, T, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2008-06-02 | Release date: | 2008-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
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2VV4
| hPPARgamma Ligand binding domain in complex with 6-oxoOTE | Descriptor: | (8E,10S,12Z)-10-hydroxy-6-oxooctadeca-8,12-dienoic acid, (8R,9Z,12Z)-8-hydroxy-6-oxooctadeca-9,12-dienoic acid, PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA | Authors: | Itoh, T, Fairall, L, Schwabe, J.W.R. | Deposit date: | 2008-06-02 | Release date: | 2008-08-19 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for the Activation of Pparg by Oxidised Fatty Acids Nat.Struct.Mol.Biol., 15, 2008
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2XTE
| Structure of the TBL1 tetramerisation domain | Descriptor: | F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X | Authors: | Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R. | Deposit date: | 2010-10-06 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.9 Å) | Cite: | Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery. Nat.Struct.Mol.Biol., 18, 2011
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2XTC
| Structure of the TBL1 tetramerisation domain | Descriptor: | F-BOX-LIKE/WD REPEAT-CONTAINING PROTEIN TBL1X | Authors: | Oberoi, J, Fairall, L, Watson, P.J, Greenwood, J.A, Schwabe, J.W.R. | Deposit date: | 2010-10-06 | Release date: | 2011-01-19 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.22 Å) | Cite: | Structural Basis for the Assembly of the Smrt/Ncor Core Transcriptional Repression Machinery. Nat.Struct.Mol.Biol., 18, 2011
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