2YHO

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor

Summary for 2YHO

Related2YHN 2C4P
DescriptorE3 UBIQUITIN-PROTEIN LIGASE MYLIP, UBIQUITIN-CONJUGATING ENZYME E2 D1, ZINC ION, ... (5 entities in total)
Functional Keywordsligase, e2 ligase-e3 ligase complex, ring zinc-finger, ubl conjugation pathway
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationCytoplasm (Probable) Q8WY64
Cytoplasm P51668
Total number of polymer chains8
Total molecular weight103500.87
Authors
Fairall, L.,Goult, B.T.,Millard, C.J.,Tontonoz, P.,Schwabe, J.W.R. (deposition date: 2011-05-04, release date: 2011-06-29, Last modification date: 2011-07-13)
Primary citation
Zhang, L.,Fairall, L.,Goult, B.T.,Calkin, A.C.,Hong, C.,Millard, C.J.,Tontonoz, P.,Schwabe, J.W.
The Idol-Ube2D Complex Mediates Sterol-Dependent Degradation of the Ldl Receptor.
Genes Dev., 25:1262-, 2011
PubMed: 21685362 (PDB entries with the same primary citation)
DOI: 10.1101/GAD.2056211
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.1 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.22690.4%5.7%2.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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