4A69

Structure of HDAC3 bound to corepressor and inositol tetraphosphate

Summary for 4A69

Related1R2B 1XC5 1KKQ
DescriptorHISTONE DEACETYLASE 3,, NUCLEAR RECEPTOR COREPRESSOR 2, ZINC ION, ... (8 entities in total)
Functional Keywordstranscription, hydrolase
Biological sourceHOMO SAPIENS (HUMAN)
Cellular locationNucleus O15379 Q9Y618
Total number of polymer chains4
Total molecular weight110225.27
Authors
Watson, P.J.,Fairall, L.,Santos, G.M.,Schwabe, J.W.R. (deposition date: 2011-11-01, release date: 2012-01-11, Last modification date: 2012-01-25)
Primary citation
Watson, P.J.,Fairall, L.,Santos, G.M.,Schwabe, J.W.R.
Structure of Hdac3 Bound to Co-Repressor and Inositol Tetraphosphate.
Nature, 481:335-, 2012
PubMed: 22230954 (PDB entries with the same primary citation)
DOI: 10.1038/NATURE10728
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.06 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.23450.2%2.6%4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

Molmil generated image of 4a69
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Molmil generated image of 4a69
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Molmil generated image of 4a69
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More Biological unit images

Molmil generated image of 4a69
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Molmil generated image of 4a69
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Molmil generated image of 4a69
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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (4a69.pdb1.gz [78.34 KB])
Coordinate files for Biological unit (4a69.pdb2.gz [78.01 KB])