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PDB: 22 件

1HIM
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STRUCTURAL EVIDENCE FOR INDUCED FIT AS A MECHANISM FOR ANTIBODY-ANTIGEN RECOGNITION
分子名称: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 100-108)
著者Schulze-Gahmen, U, Wilson, I.A.
登録日1992-07-08
公開日1994-01-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural evidence for induced fit as a mechanism for antibody-antigen recognition.
Science, 255, 1992
1HCK
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HUMAN CYCLIN-DEPENDENT KINASE 2
分子名称: ADENOSINE-5'-TRIPHOSPHATE, HUMAN CYCLIN-DEPENDENT KINASE 2, MAGNESIUM ION
著者Schulze-Gahmen, U, De Bondt, H.L, Kim, S.-H.
登録日1996-06-03
公開日1996-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design.
J.Med.Chem., 39, 1996
1IFH
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A DETAILED ANALYSIS OF THE FREE AND BOUND CONFORMATION OF AN ANTIBODY: X-RAY STRUCTURES OF ANTI-PEPTIDE FAB 17(SLASH)9 AND THREE DIFFERENT FAB-PEPTIDE COMPLEXES
分子名称: IGG2A-KAPPA 17/9 FAB (HEAVY CHAIN), IGG2A-KAPPA 17/9 FAB (LIGHT CHAIN), INFLUENZA HEMAGGLUTININ HA1 (STRAIN X47) (RESIDUES 101-107)
著者Schulze-Gahmen, U, Wilson, I.A.
登録日1993-05-06
公開日1993-10-31
最終更新日2024-06-05
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Detailed analysis of the free and bound conformations of an antibody. X-ray structures of Fab 17/9 and three different Fab-peptide complexes.
J.Mol.Biol., 234, 1993
1JOW
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Crystal structure of a complex of human CDK6 and a viral cyclin
分子名称: CELL DIVISION PROTEIN KINASE 6, CYCLIN HOMOLOG
著者Schulze-Gahmen, U, Kim, S.H.
登録日2001-07-31
公開日2002-02-27
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural basis for CDK6 activation by a virus-encoded cyclin.
Nat.Struct.Biol., 9, 2002
4OGR
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BU of 4ogr by Molmil
crystal structure of P-TEFb complex with AFF4 and Tat
分子名称: ADENOSINE, AF4/FMR2 family member 4, Cyclin-T1, ...
著者Schulze-Gahmen, U, Alber, T.
登録日2014-01-16
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献AFF4 binding to Tat-P-TEFb indirectly stimulates TAR recognition of super elongation complexes at the HIV promoter.
Elife, 3, 2014
5L1Z
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TAR complex with HIV-1 Tat-AFF4-P-TEFb
分子名称: AF4/FMR2 family member 4, Cyclin-T1, Cyclin-dependent kinase 9, ...
著者Schulze-Gahmen, U, Hurley, J.
登録日2016-07-29
公開日2016-10-26
最終更新日2024-10-30
実験手法X-RAY DIFFRACTION (5.9 Å)
主引用文献Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.
Elife, 5, 2016
2HY8
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PAK1 complex with ST2001
分子名称: (5S,6R,7R,9R)-12-HYDROXY-6-METHOXY-5-METHYL-7-(METHYLAMINO)-6,7,8,9-TETRAHYDRO-5H,14H-5,9-EPOXY-4B,9A,15-TRIAZADIBENZO[ B,H]CYCLONONA[1,2,3,4-JKL]CYCLOPENTA[E]-AS-INDACEN-14-ONE, Serine/threonine-protein kinase PAK 1
著者Schulze-Gahmen, U, Lu, H.
登録日2006-08-04
公開日2006-11-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal Structure of the Complex Between Human Pak1-kinase and 3-Hydroxystaurosporine
To be Published
1HCL
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HUMAN CYCLIN-DEPENDENT KINASE 2
分子名称: HUMAN CYCLIN-DEPENDENT KINASE 2
著者Schulze-Gahmen, U, De Bondt, H.L, Kim, S.-H.
登録日1996-06-03
公開日1996-12-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献High-resolution crystal structures of human cyclin-dependent kinase 2 with and without ATP: bound waters and natural ligand as guides for inhibitor design.
J.Med.Chem., 39, 1996
1BU2
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X-RAY STRUCTURE OF A VIRAL CYCLIN FROM HERPESVIRUS SAIMIRI
分子名称: CYCLIN HOMOLOG
著者Schulze-Gahmen, U, Jung, J.U, Kim, S.-H.
登録日1998-09-10
公開日1999-06-15
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Crystal structure of a viral cyclin, a positive regulator of cyclin-dependent kinase 6.
Structure Fold.Des., 7, 1999
1MGP
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Hypothetical protein TM841 from Thermotoga maritima reveals fatty acid binding function
分子名称: Hypothetical protein TM841, PALMITIC ACID
著者Schulze-Gahmen, U, Pelaschier, J, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2002-08-15
公開日2002-09-18
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a hypothetical protein, TM841 of Thermotoga maritima, reveals its function as fatty acid binding protein
Proteins, 50, 2003
1W0X
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Crystal structure of human CDK2 in complex with the inhibitor olomoucine.
分子名称: CYCLIN-DEPENDENT KINASE 2, OLOMOUCINE
著者Schulze-Gahmen, U, Meijer, L, Kim, S.-H.
登録日2004-06-14
公開日2005-01-14
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Multiple Modes of Ligand Recognition: Crystal Structures of Cyclin-Dependent Protein Kinase 2 in Complex with ATP and Two Inhibitors, Olomoucine and Isopentenyladenine.
Proteins, 22, 1995
2EXM
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Human CDK2 in complex with isopentenyladenine
分子名称: Cell division protein kinase 2, N-(3-METHYLBUT-2-EN-1-YL)-9H-PURIN-6-AMINE
著者Schulze-Gahmen, U.
登録日2005-11-08
公開日2005-12-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Multiple modes of ligand recognition: crystal structures of cyclin-dependent protein kinase 2 in complex with ATP and two inhibitors, olomoucine and isopentenyladenine.
Proteins, 22, 1995
2F2C
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X-ray structure of human CDK6-Vcyclinwith the inhibitor aminopurvalanol
分子名称: (2S)-2-({6-[(3-AMINO-5-CHLOROPHENYL)AMINO]-9-ISOPROPYL-9H-PURIN-2-YL}AMINO)-3-METHYLBUTAN-1-OL, Cell division protein kinase 6, Cyclin homolog, ...
著者Schulze-Gahmen, U, Lu, H.
登録日2005-11-16
公開日2006-06-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Toward understanding the structural basis of cyclin-dependent kinase 6 specific inhibition.
J.Med.Chem., 49, 2006
2EUF
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X-ray structure of human CDK6-Vcyclin in complex with the inhibitor PD0332991
分子名称: 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE, ACETATE ION, CALCIUM ION, ...
著者Schulze-Gahmen, U, Lu, H.
登録日2005-10-28
公開日2006-07-04
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Toward understanding the structural basis of cyclin-dependent kinase 6 specific inhibition.
J.Med.Chem., 49, 2006
1ZXJ
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Crystal structure of the hypthetical Mycoplasma protein, MPN555
分子名称: Hypothetical protein MG377 homolog
著者Schulze-Gahmen, U, Aono, S, Shengfeng, C, Yokota, H, Kim, R, Kim, S.-H, Berkeley Structural Genomics Center (BSGC)
登録日2005-06-08
公開日2005-07-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure of the hypothetical Mycoplasma protein MPN555 suggests a chaperone function.
Acta Crystallogr.,Sect.D, 61, 2005
7LMS
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Structure of human SetD3 methyl-transferase in complex with 2A protease from Coxsackievirus B3
分子名称: Actin-histidine N-methyltransferase, Protease 2A, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Verba, K.A, Schulze-Gahmen, U.
登録日2021-02-05
公開日2022-08-10
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3.
Nat Commun, 13, 2022
4IMY
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The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat
分子名称: ADENOSINE MONOPHOSPHATE, AF4/FMR2 family member 4, Cyclin-T1, ...
著者Alber, T, Schulze-Gahmen, U.
登録日2013-01-03
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献The AFF4 scaffold binds human P-TEFb adjacent to HIV Tat.
Elife, 2, 2013
1XO2
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Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin
分子名称: 3,7,3',4'-TETRAHYDROXYFLAVONE, Cell division protein kinase 6, Cyclin
著者Lu, H.S, Chang, D.J, Baratte, B, Meijer, L, Schulze-Gahmen, U.
登録日2004-10-05
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal Structure of a Human Cyclin-Dependent Kinase 6 Complex with a Flavonol Inhibitor, Fisetin.
J.Med.Chem., 48, 2005
1SOI
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CRYSTAL STRUCTURE OF NUDIX HYDROLASE DR1025 IN COMPLEX WITH SM+3
分子名称: MutT/nudix family protein, SAMARIUM (III) ION
著者Ranatunga, W, Hill, E.E, Mooster, J.L, Holbrook, E.L, Schulze-Gahmen, U, Xu, W, Bessman, M.J, Brenner, S.E, Holbrook, S.R, Berkeley Structural Genomics Center (BSGC)
登録日2004-03-15
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural Studies of the Nudix Hydrolase DR1025 From Deinococcus radiodurans and its Ligand Complexes.
J.Mol.Biol., 339, 2004
1SZ3
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CRYSTAL STRUCTURE OF NUDIX HYDROLASE DR1025 IN COMPLEXED WITH GNP AND MG+2
分子名称: MAGNESIUM ION, MutT/nudix family protein, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER
著者Ranatunga, W, Hill, E.E, Mooster, J.L, Holbrook, E.L, Schulze-Gahmen, U, Xu, W, Bessman, M.J, Brenner, S.E, Holbrook, S.R, Berkeley Structural Genomics Center (BSGC)
登録日2004-04-02
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Studies of the Nudix Hydrolase DR1025 From Deinococcus radiodurans and its Ligand Complexes.
J.Mol.Biol., 339, 2004
1SJY
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Crystal Structure of NUDIX HYDROLASE DR1025 FROM DEINOCOCCUS RADIODURANS
分子名称: MutT/nudix family protein
著者Ranatunga, W, Hill, E.E, Mooster, J.L, Holbrook, E.L, Schulze-Gahmen, U, Xu, W, Bessman, M.J, Brenner, S.E, Holbrook, S.R, Berkeley Structural Genomics Center (BSGC)
登録日2004-03-04
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.39 Å)
主引用文献Structural Studies of the Nudix Hydrolase DR1025 From Deinococcus radiodurans and its Ligand Complexes.
J.Mol.Biol., 339, 2004
1SU2
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CRYSTAL STRUCTURE OF THE NUDIX HYDROLASE DR1025 IN COMPLEX WITH ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, MutT/nudix family protein
著者Ranatunga, W, Hill, E.E, Mooster, J.L, Holbrook, E.L, Schulze-Gahmen, U, Xu, W, Bessman, M.J, Brenner, S.E, Holbrook, S.R, Berkeley Structural Genomics Center (BSGC)
登録日2004-03-26
公開日2004-05-11
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Studies of the Nudix Hydrolase DR1025 From Deinococcus radiodurans and its Ligand Complexes.
J.Mol.Biol., 339, 2004

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