1XO2
Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin
Summary for 1XO2
Entry DOI | 10.2210/pdb1xo2/pdb |
Related | 1jow |
Descriptor | Cyclin, Cell division protein kinase 6, 3,7,3',4'-TETRAHYDROXYFLAVONE (3 entities in total) |
Functional Keywords | human cyclin-dependent kinase 6, fisetin, cell cycle-transferase complex, cell cycle/transferase |
Biological source | Saimiriine herpesvirus 2 (Herpesvirus saimiri) More |
Total number of polymer chains | 2 |
Total formula weight | 64017.98 |
Authors | Lu, H.S.,Chang, D.J.,Baratte, B.,Meijer, L.,Schulze-Gahmen, U. (deposition date: 2004-10-05, release date: 2005-03-01, Last modification date: 2023-08-23) |
Primary citation | Lu, H.S.,Chang, D.J.,Baratte, B.,Meijer, L.,Schulze-Gahmen, U. Crystal Structure of a Human Cyclin-Dependent Kinase 6 Complex with a Flavonol Inhibitor, Fisetin. J.Med.Chem., 48:737-747, 2005 Cited by PubMed: 15689157DOI: 10.1021/jm049353p PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.9 Å) |
Structure validation
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