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1XO2

Crystal structure of a human cyclin-dependent kinase 6 complex with a flavonol inhibitor, fisetin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Cyclinpolymer25428665.41UniProt (Q01043)
Pfam (PF00134)
Pfam (PF09241)
Saimiriine herpesvirus 2 (Herpesvirus saimiri)V-cyclin
2B
(B)
Cell division protein kinase 6polymer30835066.31UniProt (Q00534)
Pfam (PF00069)
Homo sapiens (human)Serine/threonine-protein kinase PLSTIRE
3C
(B)
3,7,3',4'-TETRAHYDROXYFLAVONEnon-polymer286.21Chemie (FSE)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight63731.7
Non-Polymers*Number of molecules1
Total formula weight286.2
All*Total formula weight64018.0
*Water molecules are not included.

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PDB entries from 2025-07-30

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