2EUF

X-ray structure of human CDK6-Vcyclin in complex with the inhibitor PD0332991

Summary for 2EUF

• Entry DOI: 10.2210/pdb2euf/pdb
• Descriptor: viral Cyclin, Cell division protein kinase 6, CALCIUM ION, ... (7 entities in total)
• Functional Keywords: inhibitor complex of human cyclin-dependent kinase 6, cell cycle-transferase complex, cell cycle/transferase
• Biological source: Herpesvirus saimiri (strain 11); More
• Total number of polymer chains: 2
• Total formula weight: 64356.54

Authors

Schulze-Gahmen, U.,Lu, H. (deposition date: 2005-10-28, release date: 2006-07-04, Last modification date: 2024-02-14)

• Primary citation: Lu, H.,Schulze-Gahmen, U.; Toward understanding the structural basis of cyclin-dependent kinase 6 specific inhibition.; J.Med.Chem., 49:3826-3831, 2006; PubMed: 16789739; DOI: 10.1021/jm0600388

Experimental method

X-RAY DIFFRACTION (3 Å)