4FEU
| Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125 | Descriptor: | 2,6-DIHYDROANTHRA/1,9-CD/PYRAZOL-6-ONE, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-30 | Release date: | 2012-06-20 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.37 Å) | Cite: | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
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3CNV
| Crystal structure of the ligand-binding domain of a putative GntR-family transcriptional regulator from Bordetella bronchiseptica | Descriptor: | CHLORIDE ION, CITRATE ANION, Putative GntR-family transcriptional regulator | Authors: | Zimmerman, M.D, Xu, X, Cui, H, Filippova, E.V, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-03-26 | Release date: | 2008-04-29 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the ligand-binding domain of a putative GntR-family transcriptional regulator from Bordetella bronchiseptica. To be Published
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4FC9
| Structure of the C-terminal domain of the type III effector Xcv3220 (XopL) | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, uncharacterized protein | Authors: | Singer, A.U, Xu, X, Cui, H, Tan, K, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2012-05-24 | Release date: | 2012-06-13 | Last modified: | 2017-11-15 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structure of the C-terminal domain of the type III effector Xcv3220 (XopL) To be Published
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2FBI
| The crystal structure of transcriptional regulator PA4135 | Descriptor: | probable transcriptional regulator | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Cuff, M.E, Joachimiak, A, Edwards, A.M, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-12-09 | Release date: | 2005-12-20 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | The crystal structure of transcriptional regulator PA4135 To be Published
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2B0C
| The crystal structure of the putative phosphatase from Escherichia coli | Descriptor: | 1-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, putative phosphatase | Authors: | Zhang, R, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-09-13 | Release date: | 2005-11-22 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The 2.0A crystal structure of the putative phosphatase from Escherichia coli To be Published
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2LEZ
| Solution NMR structure of N-terminal domain of Salmonella effector protein PipB2. Northeast structural genomics consortium (NESG) target stt318a | Descriptor: | Secreted effector protein pipB2 | Authors: | Lemak, A, Yee, A, Houliston, S, Garcia, M, Daniels, C, Savchenko, A, Arrowsmith, C, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2011-06-27 | Release date: | 2011-07-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR solution structure of N-terminal domain of Salmonella effector protein PipB2 To be Published
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2B3M
| Crystal structure of protein AF1124 from Archaeoglobus fulgidus | Descriptor: | hypothetical protein AF1124 | Authors: | Chang, C, Skarina, T, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-09-20 | Release date: | 2005-11-01 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of protein AF1124 from Archaeoglobus fulgidus To be Published
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3TYK
| Crystal structure of aminoglycoside phosphotransferase APH(4)-Ia | Descriptor: | CHLORIDE ION, HYGROMYCIN B VARIANT, Hygromycin-B 4-O-kinase | Authors: | Stogios, P.J, Shabalin, I.G, Shakya, T, Evdokmova, E, Fan, Y, Chruszcz, M, Minor, W, Wright, G.D, Savchenko, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-09-26 | Release date: | 2011-10-12 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structure and function of APH(4)-Ia, a hygromycin B resistance enzyme. J.Biol.Chem., 286, 2011
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4FEW
| Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor pyrazolopyrimidine PP2 | Descriptor: | 1-TERT-BUTYL-3-(4-CHLORO-PHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, ACETATE ION, Aminoglycoside 3'-phosphotransferase AphA1-IAB, ... | Authors: | Stogios, P.J, Evdokimova, E, Wawrzak, Z, Minasov, G, Egorova, O, Di Leo, R, Shakya, T, Spanogiannopoulos, P, Wright, G.D, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-05-30 | Release date: | 2012-06-20 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem.J., 454, 2013
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3CNI
| Crystal structure of a domain of a putative ABC type-2 transporter from Thermotoga maritima MSB8 | Descriptor: | CALCIUM ION, Putative ABC type-2 transporter | Authors: | Filippova, E.V, Shumilin, I, Tkaczuk, K.L, Cymborowski, M, Chruszcz, M, Xu, X, Que, Q, Savchenko, A, Edwards, A.M, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-03-25 | Release date: | 2008-04-08 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural characterization of the putative ABC-type 2 transporter from Thermotoga maritima MSB8. J.Struct.Funct.Genom., 15, 2014
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3CNG
| Crystal structure of NUDIX hydrolase from Nitrosomonas europaea | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ... | Authors: | Osipiuk, J, Xu, X, Zheng, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2008-03-25 | Release date: | 2008-04-08 | Last modified: | 2017-10-25 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystal structure of NUDIX hydrolase from Nitrosomonas europaea. To be Published
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3UUW
| 1.63 Angstrom Resolution Crystal Structure of Dehydrogenase (MviM) from Clostridium difficile. | Descriptor: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | Authors: | Minasov, G, Wawrzak, Z, Kudritska, M, Grimshaw, S, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2011-11-28 | Release date: | 2011-12-21 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | 1.63 Angstrom Resolution Crystal Structure of Dehydrogenase (MviM) from Clostridium difficile. TO BE PUBLISHED
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1X7V
| Crystal structure of PA3566 from Pseudomonas aeruginosa | Descriptor: | PA3566 protein, SULFATE ION | Authors: | Sanders, D.A, Walker, J.R, Skarina, T, Gorodichtchenskaia, E, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2004-08-16 | Release date: | 2004-08-31 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.78 Å) | Cite: | The X-ray crystal structure of PA3566 from Pseudomonas aureginosa at 1.8 A resolution. Proteins, 61, 2005
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1YX1
| Crystal Structure of Protein of Unknown Function PA2260 from Pseudomonas aeruginosa, Possible Sugar Phosphate Isomerase | Descriptor: | ISOPROPYL ALCOHOL, SODIUM ION, hypothetical protein PA2260 | Authors: | Osipiuk, J, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-02-19 | Release date: | 2005-04-05 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | X-ray crystal structure of hypothetical protein PA2260 from Pseudomonas aeruginosa To be Published
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1YNB
| crystal structure of genomics APC5600 | Descriptor: | hypothetical protein AF1432 | Authors: | Dong, A, Skarina, T, Savchenko, A, Pai, E.F, Joachimiak, A, Edwards, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-01-24 | Release date: | 2005-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.76 Å) | Cite: | Crystal structure of genomics AF1432 by Sulfur SAD methods To be Published
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2IKS
| Crystal structure of N-terminal truncated DNA-binding transcriptional dual regulator from Escherichia coli K12 | Descriptor: | DNA-binding transcriptional dual regulator | Authors: | Chang, C, Evdokimova, E, Kagan, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-10-02 | Release date: | 2006-10-31 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Crystal structure of N-terminal truncated DNA-binding transcriptional
dual regulator from Escherichia coli K12 To be Published
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4EBK
| Crystal structure of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb, tobramycin-bound | Descriptor: | 1,2-ETHANEDIOL, Aminoglycoside nucleotidyltransferase, CHLORIDE ION, ... | Authors: | Stogios, P.J, Dong, A, Minasov, G, Evdokimova, E, Egorova, O, Yim, V, Kudritska, M, Courvalin, P, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-03-23 | Release date: | 2012-04-04 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystal structure of aminoglycoside 4'-O-adenylyltransferase ANT(4')-IIb, tobramycin-bound To be Published
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1ZX5
| The structure of a putative mannosephosphate isomerase from Archaeoglobus fulgidus | Descriptor: | 1,2-ETHANEDIOL, ACETIC ACID, GLYCEROL, ... | Authors: | Cuff, M.E, Skarina, T, Edwards, A, Savchenko, A, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-06-06 | Release date: | 2005-07-19 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | The structure of a putative mannosephosphate isomerase from Archaeoglobus fulgidus To be Published
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2I9C
| Crystal Structure of the Protein RPA1889 from Rhodopseudomonas palustris CGA009 | Descriptor: | ACETATE ION, Hypothetical protein RPA1889 | Authors: | Cymborowski, M.T, Evdokimova, E, Kagan, O, Chruszcz, M, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-09-05 | Release date: | 2006-10-03 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Protein RPA1889 from Rhodopseudomonas palustris CGA009 To be Published
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4EHI
| An X-ray Crystal Structure of a putative Bifunctional Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase | Descriptor: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifunctional purine biosynthesis protein PurH, SULFATE ION | Authors: | Brunzelle, J.S, Wawrzak, Z, Onopriyenko, O, Kwok, J, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-04-02 | Release date: | 2012-06-06 | Method: | X-RAY DIFFRACTION (2.28 Å) | Cite: | An X-ray Crystal Structure of a putative Bifunctional Phosphoribosylaminoimidazolecarboxamide Formyltransferase/IMP Cyclohydrolase TO BE PUBLISHED
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1YSP
| Crystal structure of the C-terminal domain of E. coli transcriptional regulator KdgR. | Descriptor: | SULFATE ION, Transcriptional regulator kdgR | Authors: | Bochkarev, A, Lunin, V.V, Ezersky, A, Evdokimova, E, Skarina, T, Xu, X, Borek, D, Joachimiak, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-02-08 | Release date: | 2005-03-22 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural study of effector binding specificity in IclR transcriptional regulators To be Published
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3RAO
| Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus ATCC 10987. | Descriptor: | Putative Luciferase-like Monooxygenase, SULFATE ION | Authors: | Domagalski, M.J, Chruszcz, M, Xu, X, Cui, H, Chin, S, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2011-03-28 | Release date: | 2011-05-11 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal Structure of the Luciferase-like Monooxygenase from Bacillus cereus ATCC 10987. To be Published
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2ID3
| Crystal structure of transcriptional regulator SCO5951 from Streptomyces coelicolor A3(2) | Descriptor: | CALCIUM ION, CHLORIDE ION, Putative transcriptional regulator | Authors: | Grabowski, M, Chruszcz, M, Koclega, K.D, Cymborowski, M, Gu, J, Xu, X, Savchenko, A, Edwards, A, Joachimiak, A, Minor, W, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2006-09-14 | Release date: | 2006-10-17 | Last modified: | 2022-04-13 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: |
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2A9S
| The crystal structure of competence/damage inducible protein CihA from Agrobacterium tumefaciens | Descriptor: | CHLORIDE ION, competence/damage-inducible protein CinA | Authors: | Lunin, V.V, Evdokimova, E, Kudritska, M, Kim, Y, Joachimiak, A, Edwards, A, Savchenko, A, Midwest Center for Structural Genomics (MCSG) | Deposit date: | 2005-07-12 | Release date: | 2005-07-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The crystal structure of competence/damage inducible protein CihA from Agrobacterium tumefaciens To be Published
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4EHJ
| An X-ray Structure of a Putative Phosphogylcerate Kinase from Francisella tularensis subsp. tularensis SCHU S4 | Descriptor: | Phosphoglycerate kinase, SULFATE ION | Authors: | Brunzelle, J.S, Wawrzak, Z, Skarina, T, Gordon, E, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2012-04-02 | Release date: | 2012-05-09 | Method: | X-RAY DIFFRACTION (2.71 Å) | Cite: | An X-ray Structure of a Putative Phosphogylcerate Kinase from Francisella tularensis subsp. tularensis SCHU S4 To be Published
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