5IWR
 
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of barium | | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, BARIUM ION, Transient receptor potential cation channel subfamily V member 6 | | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | Deposit date: | 2016-03-22 | | Release date: | 2016-06-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.85 Å) | | Cite: | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWK
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 | | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | Deposit date: | 2016-03-22 | | Release date: | 2016-06-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.247 Å) | | Cite: | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWT
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of gadolinium | | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, GADOLINIUM ATOM, Transient receptor potential cation channel subfamily V member 6 | | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | Deposit date: | 2016-03-22 | | Release date: | 2016-06-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.8 Å) | | Cite: | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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5IWP
 | | Structure of Transient Receptor Potential (TRP) channel TRPV6 in the presence of calcium | | Descriptor: | 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, CALCIUM ION, Transient receptor potential cation channel subfamily V member 6 | | Authors: | Saotome, K, Singh, A.K, Yelshanskaya, M.V, Sobolevsky, A.I. | | Deposit date: | 2016-03-22 | | Release date: | 2016-06-15 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (3.65 Å) | | Cite: | Crystal structure of the epithelial calcium channel TRPV6.
Nature, 534, 2016
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6NF6
 | | Structure of chicken Otop3 in nanodiscs | | Descriptor: | CHOLESTEROL HEMISUCCINATE, Otopetrin3 | | Authors: | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | | Deposit date: | 2018-12-18 | | Release date: | 2019-06-05 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (3.32 Å) | | Cite: | Structures of the otopetrin proton channels Otop1 and Otop3.
Nat.Struct.Mol.Biol., 26, 2019
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6NF4
 | | Structure of zebrafish Otop1 in nanodiscs | | Descriptor: | CHOLESTEROL, CHOLESTEROL HEMISUCCINATE, Otopetrin1 | | Authors: | Saotome, K, Lee, W.H, Liman, E.R, Ward, A.B. | | Deposit date: | 2018-12-18 | | Release date: | 2019-06-05 | | Last modified: | 2024-03-20 | | Method: | ELECTRON MICROSCOPY (2.98 Å) | | Cite: | Structures of the otopetrin proton channels Otop1 and Otop3.
Nat.Struct.Mol.Biol., 26, 2019
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8U4T
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8U4S
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8U4N
 | | Structure of Apo CXCR4/Gi complex | | Descriptor: | C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Saotome, K, McGoldrick, L.L, Franklin, M.C. | | Deposit date: | 2023-09-11 | | Release date: | 2024-03-13 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (2.72 Å) | | Cite: | Structural insights into CXCR4 modulation and oligomerization.
Nat.Struct.Mol.Biol., 2024
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8U4R
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8U4P
 | | Structure of AMD3100-bound CXCR4/Gi complex | | Descriptor: | C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Saotome, K, McGoldrick, L.L, Franklin, M.C. | | Deposit date: | 2023-09-11 | | Release date: | 2024-03-13 | | Last modified: | 2024-10-02 | | Method: | ELECTRON MICROSCOPY (3.15 Å) | | Cite: | Structural insights into CXCR4 modulation and oligomerization.
Nat.Struct.Mol.Biol., 2024
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8U4O
 | | Structure of CXCL12-bound CXCR4/Gi complex | | Descriptor: | C-X-C chemokine receptor type 4, CHOLESTEROL, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | | Authors: | Saotome, K, McGoldrick, L.L, Franklin, M.C. | | Deposit date: | 2023-09-11 | | Release date: | 2024-03-13 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.29 Å) | | Cite: | Structural insights into CXCR4 modulation and oligomerization.
Nat.Struct.Mol.Biol., 2024
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8U4Q
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8ES9
 | | CryoEM structure of PN45428 TCR-CD3 in complex with HLA-A2 MAGEA4 | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | | Authors: | Saotome, K, Franklin, M.C. | | Deposit date: | 2022-10-13 | | Release date: | 2023-05-03 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.25 Å) | | Cite: | Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
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8ES8
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8ESA
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8ES7
 | | CryoEM structure of PN45545 TCR-CD3 complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHOLESTEROL HEMISUCCINATE, ... | | Authors: | Saotome, K, Franklin, M.C. | | Deposit date: | 2022-10-13 | | Release date: | 2023-05-03 | | Last modified: | 2024-10-30 | | Method: | ELECTRON MICROSCOPY (3.04 Å) | | Cite: | Structural analysis of cancer-relevant TCR-CD3 and peptide-MHC complexes by cryoEM.
Nat Commun, 14, 2023
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8ESB
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8FJB
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8FJA
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6BPZ
 | | Structure of the mechanically activated ion channel Piezo1 | | Descriptor: | Piezo-type mechanosensitive ion channel component 1,Piezo-type mechanosensitive ion channel component 1,mouse Piezo1,Piezo-type mechanosensitive ion channel component 1,Piezo-type mechanosensitive ion channel component 1 | | Authors: | Saotome, K, Kefauver, J.M, Patapoutian, A, Ward, A.B. | | Deposit date: | 2017-11-27 | | Release date: | 2017-12-27 | | Last modified: | 2019-12-18 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | Structure of the mechanically activated ion channel Piezo1.
Nature, 554, 2018
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6XDG
 | | Complex of SARS-CoV-2 receptor binding domain with the Fab fragments of two neutralizing antibodies | | Descriptor: | REGN10933 antibody Fab fragment heavy chain, REGN10933 antibody Fab fragment light chain, REGN10987 antibody Fab fragment heavy chain, ... | | Authors: | Franklin, M.C, Saotome, K, Romero Hernandez, A, Zhou, Y. | | Deposit date: | 2020-06-10 | | Release date: | 2020-06-24 | | Last modified: | 2021-01-27 | | Method: | ELECTRON MICROSCOPY (3.9 Å) | | Cite: | Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.
Science, 369, 2020
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5WOA
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5WO7
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5WO6
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