1QNS
 
 | | The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE, ... | | 著者 | Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M. | | 登録日 | 1999-10-20 | | 公開日 | 2000-10-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5
Acta Crystallogr.,Sect.D, 56, 2000
|
|
1H4G
 | | Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre | | 分子名称: | SULFATE ION, XYLANASE, beta-D-xylopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-xylopyranose | | 著者 | Sabini, E, Wilson, K.S, Danielsen, S, Schulein, M, Davies, G.J. | | 登録日 | 2001-05-11 | | 公開日 | 2002-05-09 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.1 Å) | | 主引用文献 | Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase.
Chem.Biol., 6, 1999
|
|
1H4H
 | | Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre | | 分子名称: | XYLANASE, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose | | 著者 | Sabini, E, Wilson, K.S, Danielsen, S, Schulein, M, Davies, G.J. | | 登録日 | 2001-05-11 | | 公開日 | 2002-05-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase.
Chem.Biol., 6, 1999
|
|
2NO6
 | | C4S dCK variant of dCK in complex with FTC+ADP | | 分子名称: | 4-AMINO-5-FLUORO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | | 著者 | Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A. | | 登録日 | 2006-10-25 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
|
|
2NOA
 | | The structure of deoxycytidine kinase complexed with lamivudine and ADP. | | 分子名称: | 4-AMINO-1-[(2R,5S)-2-(HYDROXYMETHYL)-1,3-OXATHIOLAN-5-YL]PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2006-10-25 | | 公開日 | 2007-02-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural basis for activation of the therapeutic L-nucleoside analogs 3TC and troxacitabine by human deoxycytidine kinase.
Nucleic Acids Res., 35, 2007
|
|
2NO0
 | | C4S dCK variant of dCK in complex with gemcitabine+ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, GEMCITABINE | | 著者 | Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A. | | 登録日 | 2006-10-24 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
|
|
2NO1
 | | C4S dCK variant of dCK in complex with D-dC+ADP | | 分子名称: | 2'-DEOXYCYTIDINE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | | 著者 | Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A. | | 登録日 | 2006-10-24 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.91 Å) | | 主引用文献 | Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
|
|
2NO9
 | |
2NO7
 | | C4S dCK variant of dCK in complex with L-dC+ADP | | 分子名称: | 4-AMINO-1-(2-DEOXY-BETA-L-ERYTHRO-PENTOFURANOSYL)PYRIMIDIN-2(1H)-ONE, ADENOSINE-5'-DIPHOSPHATE, deoxycytidine kinase | | 著者 | Sabini, E, Hazra, S, Konrad, M, Burley, S.K, Lavie, A. | | 登録日 | 2006-10-25 | | 公開日 | 2007-07-03 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Nonenantioselectivity Property of Human Deoxycytidine Kinase Explained by Structures of the Enzyme in Complex with l- and d-Nucleosides.
J.Med.Chem., 50, 2007
|
|
2ZIA
 | |
2ZI9
 | |
2ZI4
 | | C4S dCK variant of dCK in complex with L-dA+ADP | | 分子名称: | (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, ... | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-04-22 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
|
|
2ZI3
 | |
2ZI7
 | | C4S dCK variant of dCK in complex with D-dG+UDP | | 分子名称: | 2'-DEOXY-GUANOSINE, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-07-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | Elucidation of different binding modes of purine nucleosides to human deoxycytidine kinase
J.Med.Chem., 51, 2008
|
|
2ZI5
 | | C4S dCK variant of dCK in complex with L-dA+UDP | | 分子名称: | (2S,3R,5S)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
|
|
2ZI6
 | | C4S dCK variant of dCK in complex with D-dA+UDP | | 分子名称: | (2R,3S,5R)-5-(6-amino-9H-purin-9-yl)-tetrahydro-2-(hydroxymethyl)furan-3-ol, Deoxycytidine kinase, URIDINE-5'-DIPHOSPHATE | | 著者 | Sabini, E, Lavie, A. | | 登録日 | 2008-02-13 | | 公開日 | 2008-04-22 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Structural basis for substrate promiscuity of dCK
J.Mol.Biol., 378, 2008
|
|
1P60
 | | Structure of human dCK complexed with 2'-Deoxycytidine and ADP, Space group C 2 2 21 | | 分子名称: | 2'-DEOXYCYTIDINE, ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase | | 著者 | Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A. | | 登録日 | 2003-04-28 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003
|
|
1QNO
 | | The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE | | 著者 | Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M. | | 登録日 | 1999-10-20 | | 公開日 | 2000-10-22 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
|
|
1QNP
 | | The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE, GLYCEROL, ... | | 著者 | Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M. | | 登録日 | 1999-10-20 | | 公開日 | 2000-10-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
|
|
1QNR
 | | The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE, GLYCEROL, ... | | 著者 | Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M. | | 登録日 | 1999-10-20 | | 公開日 | 2000-10-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
|
|
1QNQ
 | | The 3-D structure of a Trichoderma reesei b-mannanase from glycoside hydrolase family 5 | | 分子名称: | 2,2':6',2''-TERPYRIDINE PLATINUM(II) Chloride, 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-1,4-B-D-MANNANASE, ... | | 著者 | Sabini, E, Schubert, H, Murshudov, G, Wilson, K.S, Siika-Aho, M, Penttila, M. | | 登録日 | 1999-10-20 | | 公開日 | 2000-10-19 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The Three-Dimensional Structure of a Trichoderma Reesei Beta-Mannanase from Glycoside Hydrolase Family 5.
Acta Crystallogr.,Sect.D, 56, 2000
|
|
1P62
 | | Structure of human dCK complexed with gemcitabine and ADP-MG | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Deoxycytidine kinase, GEMCITABINE, ... | | 著者 | Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A. | | 登録日 | 2003-04-28 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003
|
|
1P5Z
 | | Structure of human dCK complexed with cytarabine and ADP-MG | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CYTARABINE, Deoxycytidine kinase, ... | | 著者 | Sabini, E, Ort, S, Monnerjahn, C, Konrad, M, Lavie, A. | | 登録日 | 2003-04-28 | | 公開日 | 2003-07-01 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of human dCK suggests strategies to improve anticancer and antiviral therapy
Nat.Struct.Biol., 10, 2003
|
|
1QH6
 | | CATALYSIS AND SPECIFICITY IN ENZYMATIC GLYCOSIDE HYDROLASES: A 2,5B CONFORMATION FOR THE GLYCOSYL-ENZYME INTERMIDIATE REVEALED BY THE STRUCTURE OF THE BACILLUS AGARADHAERENS FAMILY 11 XYLANASE | | 分子名称: | XYLANASE, beta-D-xylopyranose-(1-4)-2-deoxy-2-fluoro-alpha-D-xylopyranose | | 著者 | Sabini, E, Sulzenbacher, G, Dauter, M, Dauter, Z, Jorgensen, P.L, Schulein, M, Dupont, C, Davies, G.J, Wilson, K.S. | | 登録日 | 1999-05-11 | | 公開日 | 2000-05-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Catalysis and specificity in enzymatic glycoside hydrolysis: a 2,5B conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase.
Chem.Biol., 6, 1999
|
|
1QH7
 | | CATALYSIS AND SPECIFICITY IN ENZYMATIC GLYCOSIDE HYDROLASES: A 2,5B CONFORMATION FOR THE GLYCOSYL-ENZYME INTERMIDIATE REVEALED BY THE STRUCTURE OF THE BACILLUS AGARADHAERENS FAMILY 11 XYLANASE | | 分子名称: | XYLANASE, beta-D-xylopyranose | | 著者 | Sabini, E, Sulzenbacher, G, Dauter, M, Dauter, Z, Jorgensen, P.L, Schulein, M, Dupont, C, Davies, G.J, Wilson, K.S. | | 登録日 | 1999-05-11 | | 公開日 | 2000-05-17 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.78 Å) | | 主引用文献 | Catalysis and specificity in enzymatic glycoside hydrolysis: a 2,5B conformation for the glycosyl-enzyme intermediate revealed by the structure of the Bacillus agaradhaerens family 11 xylanase.
Chem.Biol., 6, 1999
|
|
