1P5Z

Structure of human dCK complexed with cytarabine and ADP-MG

Summary for 1P5Z

Entry DOI	10.2210/pdb1p5z/pdb
Related	1P60 1P61 1P62
Descriptor	Deoxycytidine kinase, MAGNESIUM ION, CYTARABINE, ... (5 entities in total)
Functional Keywords	nucleoside kinase, p-loop, arac, cytarabine, transferase
Biological source	Homo sapiens (human)
Cellular location	Nucleus: P27707
Total number of polymer chains	1
Total formula weight	31529.50
Authors	Sabini, E.,Ort, S.,Monnerjahn, C.,Konrad, M.,Lavie, A. (deposition date: 2003-04-28, release date: 2003-07-01, Last modification date: 2024-02-14)
Primary citation	Sabini, E.,Ort, S.,Monnerjahn, C.,Konrad, M.,Lavie, A. Structure of human dCK suggests strategies to improve anticancer and antiviral therapy Nat.Struct.Biol., 10:513-519, 2003 Cited by PubMed: 12808445 DOI: 10.1038/nsb942 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation