1P60

Structure of human dCK complexed with 2'-Deoxycytidine and ADP, Space group C 2 2 21

Summary for 1P60

• Entry DOI: 10.2210/pdb1p60/pdb
• Related: 1P5Z 1P61 1P62
• Descriptor: Deoxycytidine kinase, ADENOSINE-5'-DIPHOSPHATE, 2'-DEOXYCYTIDINE, ... (4 entities in total)
• Functional Keywords: nucleoside kinase, p-loop, deoxycytidine, transferase
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus: P27707
• Total number of polymer chains: 2
• Total formula weight: 62978.39

Authors

Sabini, E.,Ort, S.,Monnerjahn, C.,Konrad, M.,Lavie, A. (deposition date: 2003-04-28, release date: 2003-07-01, Last modification date: 2024-02-14)

• Primary citation: Sabini, E.,Ort, S.,Monnerjahn, C.,Konrad, M.,Lavie, A.; Structure of human dCK suggests strategies to improve anticancer and antiviral therapy; Nat.Struct.Biol., 10:513-519, 2003; PubMed: 12808445; DOI: 10.1038/nsb942

Experimental method

X-RAY DIFFRACTION (1.96 Å)