1H4H

Oligosaccharide-binding to family 11 xylanases: both covalent intermediate and mutant-product complexes display 2,5B conformations at the active-centre

Summary for 1H4H

Entry DOI	10.2210/pdb1h4h/pdb
Related	1H4G
Descriptor	XYLANASE, beta-D-xylopyranose-(1-4)-beta-D-xylopyranose-(1-4)-alpha-D-xylopyranose (3 entities in total)
Functional Keywords	glycoside hydrolase, xylanase, oligosaccharide, transition-state, intermediate, mutant, boat conformation
Biological source	BACILLUS AGARADHAERENS
Total number of polymer chains	4
Total formula weight	94904.53
Authors	Sabini, E.,Wilson, K.S.,Danielsen, S.,Schulein, M.,Davies, G.J. (deposition date: 2001-05-11, release date: 2002-05-09, Last modification date: 2023-12-13)
Primary citation	Sabini, E.,Sulzenbacher, G.,Dauter, M.,Dauter, Z.,Jorgensen, P.L.,Schulein, M.,Dupont, C.,Davies, G.J.,Wilson, K.S. Catalysis and Specificity in Enzymatic Glycoside Hydrolysis: A 2,5B Conformation for the Glycosyl-Enzyme Intermediate Revealed by the Structure of the Bacillus Agaradhaerens Family 11 Xylanase. Chem.Biol., 6:483-, 1999 Cited by PubMed: 10381409 DOI: 10.1016/S1074-5521(99)80066-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.9 Å)

Structure validation