Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 119 results

8FFF
DownloadVisualize
BU of 8fff by Molmil
Crystal structure of Staphylococcus aureus D-alanine D-alanine ligase enzyme in complex with acetate
Descriptor: ACETATE ION, D-alanine--D-alanine ligase
Authors:Jayasinghe, Y.P, Ronning, D.R.
Deposit date:2022-12-08
Release date:2024-05-08
Last modified:2024-05-15
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Staphylococcus aureus counters organic acid anion-mediated inhibition of peptidoglycan cross-linking through robust alanine racemase activity.
Biorxiv, 2024
1NL3
DownloadVisualize
BU of 1nl3 by Molmil
CRYSTAL STRUCTURE OF THE SECA PROTEIN TRANSLOCATION ATPASE FROM MYCOBACTERIUM TUBERCULOSIS in APO FORM
Descriptor: PREPROTEIN TRANSLOCASE SECA 1 SUBUNIT
Authors:Sharma, V, Arockiasamy, A, Ronning, D.R, Savva, C.G, Holzenburg, A, Braunstein, M, Jacobs Jr, W.R, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC)
Deposit date:2003-01-06
Release date:2003-03-04
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Crystal Structure of M. tuberculosis SecA, A Preprotein Translocating ATPase
Proc.Natl.Acad.Sci.USA, 100, 2003
8GLB
DownloadVisualize
BU of 8glb by Molmil
Selenomethionine Derivatized Citrate Synthase (CitA) in Mycobacterium tuberculosis with Pyruvate
Descriptor: 1,2-ETHANEDIOL, PYRUVIC ACID, citrate synthase
Authors:Pathirage, R, Ronning, D, Favrot, L.
Deposit date:2023-03-21
Release date:2023-06-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMI
DownloadVisualize
BU of 8gmi by Molmil
Citrate Synthase (CitA) in Mycobacterium tuberculosis modified by Ebselen at C143 residue
Descriptor: CITRATE ANION, N-phenyl-2-selanylbenzamide, citrate synthase
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-25
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMK
DownloadVisualize
BU of 8gmk by Molmil
Pyruvate bound structure of Citrate Synthase (CitA) in Mycobacterium Tuberculosis
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, PYRUVIC ACID, ...
Authors:Pathirage, R, Ronning, D, Yamsek, M.
Deposit date:2023-03-26
Release date:2023-06-07
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GI7
DownloadVisualize
BU of 8gi7 by Molmil
C143A variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, citrate synthase (unknown stereospecificity)
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-13
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GM9
DownloadVisualize
BU of 8gm9 by Molmil
Structure of Citrate Synthase(CitA) in Mycobacterium Tuberculosis
Descriptor: 1,2-ETHANEDIOL, ACRYLIC ACID, DI(HYDROXYETHYL)ETHER, ...
Authors:Pathirage, R, Ronning, D, Favrot, L.
Deposit date:2023-03-24
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GLL
DownloadVisualize
BU of 8gll by Molmil
R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, SULFATE ION, ...
Authors:Pathirage, R, Ronning, D, Petit, C.
Deposit date:2023-03-22
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GIW
DownloadVisualize
BU of 8giw by Molmil
C143K variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: 1,2-ETHANEDIOL, CITRATE ANION, DI(HYDROXYETHYL)ETHER, ...
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-14
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
8GMF
DownloadVisualize
BU of 8gmf by Molmil
R153M variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Descriptor: citrate synthase
Authors:Pathirage, R, Ronning, D.
Deposit date:2023-03-25
Release date:2023-06-07
Last modified:2023-11-08
Method:X-RAY DIFFRACTION (2.96 Å)
Cite:Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.
Rsc Med Chem, 14, 2023
5JPC
DownloadVisualize
BU of 5jpc by Molmil
Joint X-ray/neutron structure of MTAN complex with Formycin A
Descriptor: (1S)-1-(7-amino-1H-pyrazolo[4,3-d]pyrimidin-3-yl)-1,4-anhydro-D-ribitol, Aminodeoxyfutalosine nucleosidase
Authors:Banco, M.T, Kovalevsky, A.Y, Ronning, D.R.
Deposit date:2016-05-03
Release date:2016-11-16
Last modified:2024-03-06
Method:NEUTRON DIFFRACTION (2.5 Å), X-RAY DIFFRACTION
Cite:Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
1RZ9
DownloadVisualize
BU of 1rz9 by Molmil
Crystal Structure of AAV Rep complexed with the Rep-binding sequence
Descriptor: 26-MER, Rep protein
Authors:Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M, Dyda, F.
Deposit date:2003-12-24
Release date:2004-02-17
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:The nuclease domain of adeno-associated virus rep coordinates replication initiation using two distinct DNA recognition interfaces.
Mol.Cell, 13, 2004
5KB3
DownloadVisualize
BU of 5kb3 by Molmil
1.4 A resolution structure of Helicobacter Pylori MTAN in complexed with p-ClPh-DADMe-ImmA
Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase, MAGNESIUM ION
Authors:Banco, M.T, Ronning, D.R.
Deposit date:2016-06-02
Release date:2016-11-16
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.399 Å)
Cite:Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
2VJU
DownloadVisualize
BU of 2vju by Molmil
Crystal structure of the IS608 transposase in complex with the complete Right end 35-mer DNA and manganese
Descriptor: MANGANESE (II) ION, RIGHT END 35-MER, TRANSPOSASE ORFA
Authors:Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
Deposit date:2007-12-13
Release date:2008-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
5VT4
DownloadVisualize
BU of 5vt4 by Molmil
Sco GlgEI-V279S in complex with a pyrolidene-based methyl-phosphonate compound
Descriptor: Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase 1, {[(2R,3R,4R,5R)-3-(alpha-D-glucopyranosyloxy)-4-hydroxy-2,5-bis(hydroxymethyl)pyrrolidin-1-yl]methyl}phosphonic acid
Authors:Petit, C, Ronning, D.R, Lindenberger, J.J.
Deposit date:2017-05-15
Release date:2017-06-07
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (3.205 Å)
Cite:Zwitterionic pyrrolidene-phosphonates: inhibitors of the glycoside hydrolase-like phosphorylase Streptomyces coelicolor GlgEI-V279S.
Org. Biomol. Chem., 15, 2017
2VIC
DownloadVisualize
BU of 2vic by Molmil
CRYSTAL STRUCTURE OF THE ISHP608 TRANSPOSASE IN COMPLEX with Left end 26- mer DNA and manganese
Descriptor: 5'-D(*AP*AP*AP*GP*CP*CP*CP*CP*TP*AP *GP*CP*TP*TP*TP*TP*AP*GP*CP*TP*AP*TP*GP*GP*GP*G)-3', MANGANESE (II) ION, TRANSPOSASE ORFA
Authors:Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
Deposit date:2007-11-29
Release date:2008-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
2VHG
DownloadVisualize
BU of 2vhg by Molmil
Crystal Structure of the ISHp608 Transposase in Complex with Right End 31-mer DNA
Descriptor: MANGANESE (II) ION, RIGHT END 31-MER, TRANSPOSASE ORFA
Authors:Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
Deposit date:2007-11-21
Release date:2008-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
2VIH
DownloadVisualize
BU of 2vih by Molmil
CRYSTAL STRUCTURE OF THE IS608 TRANSPOSASE IN COMPLEX WITH Left END 26-MER DNA
Descriptor: 5'-D(*AP*AP*AP*GP*CP*CP*CP*CP*TP*AP *GP*CP*TP*TP*TP*TP*AP*GP*CP*TP*AP*TP*GP*GP*GP*G)-3', TRANSPOSASE ORFA
Authors:Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
Deposit date:2007-12-04
Release date:2008-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
5KWJ
DownloadVisualize
BU of 5kwj by Molmil
M.tb Ag85C modified at C209 by amino-ebselen
Descriptor: Diacylglycerol acyltransferase/mycolyltransferase Ag85C, ~{N}-(4-aminophenyl)-2-selanyl-benzamide
Authors:Goins, C.M, Ronning, D.R.
Deposit date:2016-07-18
Release date:2017-03-29
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Exploring Covalent Allosteric Inhibition of Antigen 85C from Mycobacterium tuberculosis by Ebselen Derivatives.
ACS Infect Dis, 3, 2017
5VNS
DownloadVisualize
BU of 5vns by Molmil
M.tb Antigen 85C Acyl-Enzyme Intermediate with Tetrahydrolipstatin
Descriptor: (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, Diacylglycerol acyltransferase/mycolyltransferase Ag85C, ...
Authors:Goins, C.M, Ronning, D.R.
Deposit date:2017-05-01
Release date:2018-01-24
Last modified:2019-12-11
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Mycolyltransferase fromMycobacterium tuberculosisin covalent complex with tetrahydrolipstatin provides insights into antigen 85 catalysis.
J. Biol. Chem., 293, 2018
2VJV
DownloadVisualize
BU of 2vjv by Molmil
Crystal structure of the IS608 transposase in complex with left end 26-mer DNA hairpin and a 6-mer DNA representing the left end cleavage site
Descriptor: 5'-D(*DA*DA*DA*DG*DC*DC*DC*DC*DT*DA*DG*DC*DTP*DT *DT*DT*DA*DG*DC*DT*DA*DT*DG*DG*DG*DGP)-3', 5'-D(*DT*DA*DT*DT*DA*DCP)-3', MAGNESIUM ION, ...
Authors:Barabas, O, Ronning, D.R, Guynet, C, Hickman, A.B, Ton-Hoang, B, Chandler, M, Dyda, F.
Deposit date:2007-12-13
Release date:2008-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Mechanism of is200/is605 Family DNA Transposases: Activation and Transposon-Directed Target Site Selection.
Cell(Cambridge,Mass.), 132, 2008
1YNK
DownloadVisualize
BU of 1ynk by Molmil
Identification of Key residues of the NC6.8 Fab antibody fragment binding to synthetic sweeteners: Crystal structure of NC6.8 co-crystalized with high potency sweetener compound SC45647
Descriptor: 2-[((R)-{[4-(AMINOMETHYL)PHENYL]AMINO}{[(1R)-1-PHENYLETHYL]AMINO}METHYL)AMINO]ETHANE-1,1-DIOL, Ig gamma heavy chain, immunoglobulin kappa light chain
Authors:Gokulan, K, Khare, S, Ronning, D.R, Linthicum, S.D, Sacchettini, J.C, Rupp, B.
Deposit date:2005-01-24
Release date:2005-08-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Cocrystal Structures of NC6.8 Fab Identify Key Interactions for High Potency Sweetener Recognition: Implications for the Design of Synthetic Sweeteners
Biochemistry, 44, 2005
5K1Z
DownloadVisualize
BU of 5k1z by Molmil
Joint X-ray/neutron structure of MTAN complex with p-ClPh-Thio-DADMe-ImmA
Descriptor: (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-{[(4-chlorophenyl)sulfanyl]methyl}pyrrolidin-3-ol, Aminodeoxyfutalosine nucleosidase
Authors:Banco, M.T, Kovalevsky, A.Y, Ronning, D.R.
Deposit date:2016-05-18
Release date:2016-11-16
Last modified:2024-03-06
Method:NEUTRON DIFFRACTION (2.6 Å), X-RAY DIFFRACTION
Cite:Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
4MQM
DownloadVisualize
BU of 4mqm by Molmil
Crystal structure of Antigen 85C in presence of Ebselen
Descriptor: Diacylglycerol acyltransferase/mycolyltransferase Ag85C
Authors:Favrot, L, Grzegorzewicz, A.E, Lajiness, D.H, Marvin, R.K, Boucau, J, Isailovic, D, Jackson, M, Ronning, D.R.
Deposit date:2013-09-16
Release date:2013-11-13
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.346 Å)
Cite:Mechanism of inhibition of Mycobacterium tuberculosis antigen 85 by ebselen.
Nat Commun, 4, 2013
1UUT
DownloadVisualize
BU of 1uut by Molmil
The Nuclease Domain of Adeno-Associated Virus Rep Complexed with the RBE' Stemloop of the Viral Inverted Terminal Repeat
Descriptor: 5'-D(*CP*AP*GP*CP*TP*CP*TP*TP*TP*GP *AP*GP*CP*TP*G)-3', CHLORIDE ION, MAGNESIUM ION, ...
Authors:Dyda, F, Hickman, A.B, Ronning, D.R, Perez, Z.N, Kotin, R.M.
Deposit date:2004-01-10
Release date:2004-02-19
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2 Å)
Cite:The Nuclease Domain of Adeno-Associated Virus Rep Coordinates Replication Initiation Using Two Distinct DNA Recognition Interfaces
Mol.Cell, 13, 2004

222624

PDB entries from 2024-07-17

PDB statisticsPDBj update infoContact PDBjnumon