8GIW
C143K variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Summary for 8GIW
| Entry DOI | 10.2210/pdb8giw/pdb |
| Descriptor | citrate synthase (unknown stereospecificity), CITRATE ANION, 1,2-ETHANEDIOL, ... (6 entities in total) |
| Functional Keywords | citrate synthesis, tca cycle, c143k variant, cytosolic protein |
| Biological source | Mycobacterium tuberculosis H37Rv |
| Total number of polymer chains | 4 |
| Total formula weight | 166540.64 |
| Authors | Pathirage, R.,Ronning, D. (deposition date: 2023-03-14, release date: 2023-06-07, Last modification date: 2023-11-08) |
| Primary citation | Pathirage, R.,Favrot, L.,Petit, C.,Yamsek, M.,Singh, S.,Mallareddy, J.R.,Rana, S.,Natarajan, A.,Ronning, D.R. Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding. Rsc Med Chem, 14:921-933, 2023 Cited by PubMed: 37252106DOI: 10.1039/d3md00058c PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (3.15 Å) |
Structure validation
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