8GIW
C143K variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | citrate synthase (unknown stereospecificity) | polymer | 379 | 41045.6 | 4 | UniProt (A0A045JB88) Pfam (PF00285) UniProt (by SIFTS) (P9WPD3) | Mycobacterium tuberculosis H37Rv | |
| 2 | E, O, U, Y (A, B, C, D) | CITRATE ANION | non-polymer | 189.1 | 4 | Chemie (FLC) | |||
| 3 | AA, BA, CA, DA, EA... (D, A, B, C) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 21 | Chemie (EDO) | |||
| 4 | N, W (A, C) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 5 | S (B) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 6 | GA, HA, IA, JA (A, B, C, D) | water | water | 18.0 | 28 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 373 (UniProt: A0A045JB88)
| PDB | External Database | Details |
|---|---|---|
| Lys 143 | Cys 143 | engineered mutation |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
| His 379 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 164182.6 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 2358.1 | |
| All* | Total formula weight | 166540.6 |
