8GLL

R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis

Summary for 8GLL

• Entry DOI: 10.2210/pdb8gll/pdb
• Descriptor: citrate synthase, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: citrate synthesis, tca cycle, r149e variant, cytosolic protein
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 8
• Total formula weight: 335195.55

Authors

Pathirage, R.,Ronning, D.,Petit, C. (deposition date: 2023-03-22, release date: 2023-06-07, Last modification date: 2023-11-08)

• Primary citation: Pathirage, R.,Favrot, L.,Petit, C.,Yamsek, M.,Singh, S.,Mallareddy, J.R.,Rana, S.,Natarajan, A.,Ronning, D.R.; Mycobacterium tuberculosis CitA activity is modulated by cysteine oxidation and pyruvate binding.; Rsc Med Chem, 14:921-933, 2023; PubMed: 37252106; DOI: 10.1039/d3md00058c

Experimental method

X-RAY DIFFRACTION (2.65 Å)