8GLL
R149E variant of Citrate Synthase (CitA) in Mycobacterium tuberculosis
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | citrate synthase | polymer | 379 | 40991.5 | 8 | UniProt (A0A045JB88) Pfam (PF00285) UniProt (by SIFTS) (P9WPD3) | Mycobacterium tuberculosis H37Rv | |
| 2 | AA, AC, AD, BA, BB... (B, E, H, D, C...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 75 | Chemie (EDO) | |||
| 3 | AB, CB, DB, GA, IB... (D, C, A, E, H...) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 11 | Chemie (PEG) | |||
| 4 | CA, DC, DD, EC, ED... (B, E, H, F, G...) | SULFATE ION | non-polymer | 96.1 | 15 | Chemie (SO4) | |||
| 5 | FD, GD, HD, ID, JD... (A, B, C, D, E...) | water | water | 18.0 | 581 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 373 (UniProt: A0A045JB88)
| PDB | External Database | Details |
|---|---|---|
| Glu 149 | Arg 149 | engineered mutation |
| His 374 | - | expression tag |
| His 375 | - | expression tag |
| His 376 | - | expression tag |
| His 377 | - | expression tag |
| His 378 | - | expression tag |
| His 379 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 327932.2 | |
| Non-Polymers* | Number of molecules | 101 |
| Total formula weight | 7263.4 | |
| All* | Total formula weight | 335195.5 |
