5VNS

M.tb Antigen 85C Acyl-Enzyme Intermediate with Tetrahydrolipstatin

Summary for 5VNS

Entry DOI	10.2210/pdb5vns/pdb
Descriptor	Diacylglycerol acyltransferase/mycolyltransferase Ag85C, (2S,3S,5S)-5-[(N-FORMYL-L-LEUCYL)OXY]-2-HEXYL-3-HYDROXYHEXADECANOIC ACID, (4S)-2-METHYL-2,4-PENTANEDIOL, ... (5 entities in total)
Functional Keywords	enzyme-acyl intermediate, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	1
Total formula weight	34177.07
Authors	Goins, C.M.,Ronning, D.R. (deposition date: 2017-05-01, release date: 2018-01-24, Last modification date: 2019-12-11)
Primary citation	Goins, C.M.,Dajnowicz, S.,Smith, M.D.,Parks, J.M.,Ronning, D.R. Mycolyltransferase fromMycobacterium tuberculosisin covalent complex with tetrahydrolipstatin provides insights into antigen 85 catalysis. J. Biol. Chem., 293:3651-3662, 2018 Cited by PubMed: 29352107 DOI: 10.1074/jbc.RA117.001681 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.45 Å)

Structure validation