6M31
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1E8V
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![BU of 1e8v by Molmil](/molmil-images/mine/1e8v) | Structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase | Descriptor: | 2-DEOXY-2,3-DEHYDRO-N-ACETYL-NEURAMINIC ACID, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Crennell, S, Takimoto, T, Portner, A, Taylor, G. | Deposit date: | 2000-10-01 | Release date: | 2001-04-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Multifunctional Paramyxovirus Hemagglutinin-Neuraminidase Nat.Struct.Biol., 7, 2000
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1E8U
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![BU of 1e8u by Molmil](/molmil-images/mine/1e8u) | Structure of the multifunctional paramyxovirus hemagglutinin-neuraminidase | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, HEMAGGLUTININ-NEURAMINIDASE, ... | Authors: | Crennell, S, Takimoto, T, Portner, A, Taylor, G. | Deposit date: | 2000-10-01 | Release date: | 2001-04-03 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal Structure of the Multifunctional Paramyxovirus Hemagglutinin-Neuraminidase Nat.Struct.Biol., 7, 2000
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2FXV
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![BU of 2fxv by Molmil](/molmil-images/mine/2fxv) | Bacillus subtilis Xanthine Phosphoribosyltransferase in Complex with Guanosine 5'-monophosphate (GMP) | Descriptor: | GLYCEROL, GUANOSINE-5'-MONOPHOSPHATE, Xanthine phosphoribosyltransferase | Authors: | Arent, S, Kadziola, A, Larsen, S, Neuhard, J, Jensen, K.F. | Deposit date: | 2006-02-06 | Release date: | 2006-06-20 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The Extraordinary Specificity of Xanthine Phosphoribosyltransferase from Bacillus subtilis Elucidated
by Reaction Kinetics, Ligand Binding, and Crystallography Biochemistry, 45, 2006
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7NVR
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![BU of 7nvr by Molmil](/molmil-images/mine/7nvr) | Human Mediator with RNA Polymerase II Pre-initiation complex | Descriptor: | CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... | Authors: | Rengachari, S, Schilbach, S, Aibara, S, Cramer, P. | Deposit date: | 2021-03-15 | Release date: | 2021-05-05 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Structures of mammalian RNA polymerase II pre-initiation complexes. Nature, 594, 2021
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7ZX8
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![BU of 7zx8 by Molmil](/molmil-images/mine/7zx8) | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-20 | Release date: | 2022-12-07 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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7ZWD
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![BU of 7zwd by Molmil](/molmil-images/mine/7zwd) | Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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7ZX7
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![BU of 7zx7 by Molmil](/molmil-images/mine/7zx7) | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (CC) | Descriptor: | DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, DNA-directed RNA polymerase II subunit RPB3, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-20 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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7ZXE
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![BU of 7zxe by Molmil](/molmil-images/mine/7zxe) | Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC) | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-20 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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7ZWC
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![BU of 7zwc by Molmil](/molmil-images/mine/7zwc) | Structure of SNAPc:TBP-TFIIA-TFIIB sub-complex bound to U5 snRNA promoter | Descriptor: | Non-template strand, TATA-box-binding protein, Template strand, ... | Authors: | Rengachari, S, Schilbach, S, Kaliyappan, T, Gouge, J, Zumer, K, Schwarz, J, Urlaub, H, Dienemann, C, Vannini, A, Cramer, P. | Deposit date: | 2022-05-19 | Release date: | 2022-11-30 | Last modified: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29, 2022
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5JTE
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![BU of 5jte by Molmil](/molmil-images/mine/5jte) | Cryo-EM structure of an ErmBL-stalled ribosome in complex with A-, P-, and E-tRNA | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Arenz, S, Bock, L.V, Graf, M, Innis, C.A, Beckmann, R, Grubmueller, H, Vaiana, A.C, Wilson, D.N. | Deposit date: | 2016-05-09 | Release date: | 2016-07-20 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. Nat Commun, 7, 2016
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5KCS
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![BU of 5kcs by Molmil](/molmil-images/mine/5kcs) | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Evernimycin, mRNA, TetM and P-site tRNA at 3.9A resolution | Descriptor: | (2R,3R,4R,6S)-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7S,7aR)-6-{[(2S,3R,4R,5S,6R)-2-{[(2R,3S,4S,5S,6S)-6-({(2R,3aS,3a'R,6S,7R,7'R,7aS,7a'S)-7'-[(2,4-dihydroxy-6-methylbenzoyl)oxy]-7-hydroxyoctahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-4-hydroxy-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-3-hydroxy-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4',7-dihydroxy-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-4-{[(2R,4S,5R,6S)-5-methoxy-4,6-dimethyl-4-nitrotetrahydro-2H-pyran-2-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N. | Deposit date: | 2016-06-06 | Release date: | 2016-08-17 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome. Proc.Natl.Acad.Sci.USA, 113, 2016
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7U8G
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![BU of 7u8g by Molmil](/molmil-images/mine/7u8g) | Cryo-EM structure of the core human NADPH oxidase NOX2 | Descriptor: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose, 7G5 - heavy chain, ... | Authors: | Noreng, S, Ota, N, Sun, Y, Masureel, M, Payandeh, J, Yi, T, Koerber, J.T. | Deposit date: | 2022-03-08 | Release date: | 2022-10-26 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Structure of the core human NADPH oxidase NOX2. Nat Commun, 13, 2022
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5KCR
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![BU of 5kcr by Molmil](/molmil-images/mine/5kcr) | Cryo-EM structure of the Escherichia coli 70S ribosome in complex with antibiotic Avilamycin C, mRNA and P-site tRNA at 3.6A resolution | Descriptor: | (2R,3S,4R,6S)-4-hydroxy-6-{[(2R,3aR,4R,4'R,5'S,6S,6'R,7aR)-4'-hydroxy-6-{[(2S,3R,4R,5S,6R)-3-hydroxy-2-{[(2R,3S,4S,5S,6S)-4-hydroxy-6-({(2R,3aS,3a'R,6S,6'R,7R,7'R,7aR,7a'R)-7'-hydroxy-7'-[(1S)-1-hydroxyethyl]-6'-methyl-7-[(2-methylpropanoyl)oxy]octahydro-4H-2,4'-spirobi[[1,3]dioxolo[4,5-c]pyran]-6-yl}oxy)-5-methoxy-2-(methoxymethyl)tetrahydro-2H-pyran-3-yl]oxy}-5-methoxy-6-methyltetrahydro-2H-pyran-4-yl]oxy}-4,6',7a-trimethyloctahydro-4H-spiro[1,3-dioxolo[4,5-c]pyran-2,2'-pyran]-5'-yl]oxy}-2-methyltetrahydro-2H-pyran-3-yl 3,5-dichloro-4-hydroxy-2-methoxy-6-methylbenzoate (non-preferred name), 16S Ribosomal RNA, 23S Ribosomal RNA, ... | Authors: | Arenz, S, Juette, M.F, Graf, M, Nguyen, F, Huter, P, Polikanov, Y.S, Blanchard, S.C, Wilson, D.N. | Deposit date: | 2016-06-06 | Release date: | 2016-08-17 | Last modified: | 2019-12-25 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structures of the orthosomycin antibiotics avilamycin and evernimicin in complex with the bacterial 70S ribosome. Proc.Natl.Acad.Sci.USA, 113, 2016
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5JU8
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![BU of 5ju8 by Molmil](/molmil-images/mine/5ju8) | Cryo-EM structure of an ErmBL-stalled ribosome in complex with P-, and E-tRNA | Descriptor: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | Authors: | Arenz, S, Bock, L.V, Graf, M, Innis, C.A, Beckmann, R, Grubmueller, H, Vaiana, A.C, Wilson, D.N. | Deposit date: | 2016-05-10 | Release date: | 2016-07-20 | Last modified: | 2019-12-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | A combined cryo-EM and molecular dynamics approach reveals the mechanism of ErmBL-mediated translation arrest. Nat Commun, 7, 2016
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5L3P
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![BU of 5l3p by Molmil](/molmil-images/mine/5l3p) | |
5X09
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![BU of 5x09 by Molmil](/molmil-images/mine/5x09) | Crystal structure of subunit A mutant P235A/S238C of the A-ATP synthase from pyrococcus horikoshii OT3 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETIC ACID, ... | Authors: | Dhirendra, S, Gruber, G. | Deposit date: | 2017-01-20 | Release date: | 2017-11-29 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Crystallographic and enzymatic insights into the mechanisms of Mg-ADP inhibition in the A1 complex of the A1AO ATP synthase J. Struct. Biol., 201, 2018
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6BQN
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![BU of 6bqn by Molmil](/molmil-images/mine/6bqn) | Cryo-EM structure of ENaC | Descriptor: | 10D4 fab, 7B1 fab, EGFP-SCNN1G chimera, ... | Authors: | Noreng, S, Bharadwaj, A, Posert, R, Yoshioka, C, Baconguis, I. | Deposit date: | 2017-11-28 | Release date: | 2018-10-10 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Structure of the human epithelial sodium channel by cryo-electron microscopy. Elife, 7, 2018
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4XEY
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![BU of 4xey by Molmil](/molmil-images/mine/4xey) | |
3J7Z
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![BU of 3j7z by Molmil](/molmil-images/mine/3j7z) | Structure of the E. coli 50S subunit with ErmCL nascent chain | Descriptor: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | Authors: | Arenz, S, Meydan, S, Starosta, A.L, Berninghausen, O, Beckmann, R, Vazquez-Laslop, N, Wilson, D.N. | Deposit date: | 2014-08-27 | Release date: | 2014-10-22 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | Drug Sensing by the Ribosome Induces Translational Arrest via Active Site Perturbation. Mol.Cell, 56, 2014
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4KE8
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![BU of 4ke8 by Molmil](/molmil-images/mine/4ke8) | Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with monopalmitoyl glycerol analogue | Descriptor: | Thermostable monoacylglycerol lipase, tetradecyl hydrogen (R)-(3-azidopropyl)phosphonate | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2019-07-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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4KE6
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![BU of 4ke6 by Molmil](/molmil-images/mine/4ke6) | Crystal structure D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in complex with 1-rac-lauroyl glycerol | Descriptor: | (2R)-2,3-dihydroxypropyl dodecanoate, (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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4KE7
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![BU of 4ke7 by Molmil](/molmil-images/mine/4ke7) | Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with an 1-myristoyl glycerol analogue | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase, dodecyl hydrogen (S)-(3-azidopropyl)phosphonate | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (1.699 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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4KEA
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![BU of 4kea by Molmil](/molmil-images/mine/4kea) | Crystal structure of D196N mutant of Monoglyceride lipase from Bacillus sp. H257 in space group P212121 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Thermostable monoacylglycerol lipase | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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4KE9
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![BU of 4ke9 by Molmil](/molmil-images/mine/4ke9) | Crystal structure of Monoglyceride lipase from Bacillus sp. H257 in complex with an 1-stearyol glycerol analogue | Descriptor: | Thermostable monoacylglycerol lipase, hexadecyl hydrogen (R)-(3-azidopropyl)phosphonate | Authors: | Rengachari, S, Aschauer, P, Gruber, K, Dreveny, I, Oberer, M. | Deposit date: | 2013-04-25 | Release date: | 2013-09-18 | Last modified: | 2013-11-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Conformational plasticity and ligand binding of bacterial monoacylglycerol lipase. J.Biol.Chem., 288, 2013
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