7ZWD

Structure of SNAPc containing Pol II pre-initiation complex bound to U5 snRNA promoter (CC)

This is a non-PDB format compatible entry.

Summary for 7ZWD

• Entry DOI: 10.2210/pdb7zwd/pdb
• EMDB information: 14997
• Descriptor: DNA-directed RNA polymerase subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC5, RNA polymerase II subunit J, ... (26 entities in total)
• Functional Keywords: rna polymerase ii, pol ii, pic, snapc, snrna, u5 promoter, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 24
• Total formula weight: 1051618.42

Authors

Rengachari, S.,Schilbach, S.,Kaliyappan, T.,Gouge, J.,Zumer, K.,Schwarz, J.,Urlaub, H.,Dienemann, C.,Vannini, A.,Cramer, P. (deposition date: 2022-05-19, release date: 2022-11-30, Last modification date: 2022-12-28)

• Primary citation: Rengachari, S.,Schilbach, S.,Kaliyappan, T.,Gouge, J.,Zumer, K.,Schwarz, J.,Urlaub, H.,Dienemann, C.,Vannini, A.,Cramer, P.; Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II.; Nat.Struct.Mol.Biol., 29:1159-1169, 2022; PubMed: 36424526; DOI: 10.1038/s41594-022-00857-w

Experimental method

ELECTRON MICROSCOPY (3 Å)