7ZX8
Structure of SNAPc containing Pol II pre-initiation complex bound to U1 snRNA promoter (OC)
This is a non-PDB format compatible entry.
Summary for 7ZX8
Entry DOI | 10.2210/pdb7zx8/pdb |
EMDB information | 15007 |
Descriptor | DNA-directed RNA polymerase subunit, DNA-directed RNA polymerases I, II, and III subunit RPABC5, RNA polymerase II subunit J, ... (26 entities in total) |
Functional Keywords | rna polymerase ii, pol ii, pic, snapc, snrna, u1 promoter, transcription |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 24 |
Total formula weight | 1051627.33 |
Authors | Rengachari, S.,Schilbach, S.,Kaliyappan, T.,Gouge, J.,Zumer, K.,Schwarz, J.,Urlaub, H.,Dienemann, C.,Vannini, A.,Cramer, P. (deposition date: 2022-05-20, release date: 2022-12-07, Last modification date: 2024-07-24) |
Primary citation | Rengachari, S.,Schilbach, S.,Kaliyappan, T.,Gouge, J.,Zumer, K.,Schwarz, J.,Urlaub, H.,Dienemann, C.,Vannini, A.,Cramer, P. Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II. Nat.Struct.Mol.Biol., 29:1159-1169, 2022 Cited by PubMed: 36424526DOI: 10.1038/s41594-022-00857-w PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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