5C4W
| Crystal structure of coxsackievirus A16 | 分子名称: | CHLORIDE ION, POTASSIUM ION, SODIUM ION, ... | 著者 | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | 登録日 | 2015-06-18 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity. J.Virol., 89, 2015
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5C9A
| Crystal structure of empty coxsackievirus A16 particle | 分子名称: | CHLORIDE ION, POTASSIUM ION, SPHINGOSINE, ... | 著者 | Ren, J, Wang, X, Zhu, L, Hu, Z, Gao, Q, Yang, P, Li, X, Wang, J, Shen, X, Fry, E.E, Rao, Z, Stuart, D.I. | 登録日 | 2015-06-26 | 公開日 | 2015-08-26 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structures of Coxsackievirus A16 Capsids with Native Antigenicity: Implications for Particle Expansion, Receptor Binding, and Immunogenicity. J.Virol., 89, 2015
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4MJS
| crystal structure of a PB1 complex | 分子名称: | 1,2-ETHANEDIOL, Protein kinase C zeta type, Sequestosome-1 | 著者 | Ren, J, Wang, Z.X, Wu, J.W. | 登録日 | 2013-09-04 | 公開日 | 2014-08-27 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and biochemical insights into the homotypic PB1-PB1 complex between PKC zeta and p62 Sci China Life Sci, 57, 2014
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5BNQ
| Crystal structure of hRANKL-mRANK complex | 分子名称: | CHLORIDE ION, PHOSPHATE ION, SODIUM ION, ... | 著者 | Ren, J. | 登録日 | 2015-05-26 | 公開日 | 2015-10-14 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | A RANKL mutant used as an inter-species vaccine for efficient immunotherapy of osteoporosis. Sci Rep, 5, 2015
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4YU8
| Crystal structure of Neuroblastoma suppressor of tumorigenicity 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, Neuroblastoma suppressor of tumorigenicity 1 | 著者 | Ren, J, Nettleship, J.E, Stammers, D.K, Owens, R.J, Oxford Protein Production Facility (OPPF) | 登録日 | 2015-03-18 | 公開日 | 2015-03-25 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Crystal structure of Neuroblastoma suppressor of tumorigenicity 1 To Be Published
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1C0U
| CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH BM+50.0934 | 分子名称: | (R)-(+) 5(9BH)-OXO-9B-PHENYL-2,3-DIHYDROTHIAZOLO[2,3-A]ISOINDOL-3-CARBOXYLIC ACID METHYL ESTER, HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN), HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN) | 著者 | Ren, J, Esnouf, R.M, Hopkins, A.L, Stuart, D.I, Stammers, D.K. | 登録日 | 1999-07-19 | 公開日 | 2000-07-19 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (2.52 Å) | 主引用文献 | Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies. J.Med.Chem., 42, 1999
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1C0T
| CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH BM+21.1326 | 分子名称: | (R)-(+)9B-(3-METHYL)PHENYL-2,3-DIHYDROTHIAZOLO[2,3-A]ISOINDOL-5(9BH)-ONE, HIV-1 REVERSE TRANSCRIPTASE (A-CHAIN), HIV-1 REVERSE TRANSCRIPTASE (B-CHAIN) | 著者 | Ren, J, Esnouf, R.M, Hopkins, A.L, Stuart, D.I, Stammers, D.K. | 登録日 | 1999-07-19 | 公開日 | 2000-07-19 | 最終更新日 | 2014-11-12 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystallographic analysis of the binding modes of thiazoloisoindolinone non-nucleoside inhibitors to HIV-1 reverse transcriptase and comparison with modeling studies. J.Med.Chem., 42, 1999
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1KLM
| HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH BHAP U-90152 | 分子名称: | (1-(5-METHANSULPHONAMIDO-1H-INDOL-2-YL-CARBONYL)4-[METHYLAMINO)PYRIDINYL]PIPERAZINE, HIV-1 REVERSE TRANSCRIPTASE | 著者 | Ren, J, Esnouf, R.M, Stammers, D.K, Stuart, D.I. | 登録日 | 1997-03-17 | 公開日 | 1998-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | 主引用文献 | Unique features in the structure of the complex between HIV-1 reverse transcriptase and the bis(heteroaryl)piperazine (BHAP) U-90152 explain resistance mutations for this nonnucleoside inhibitor. Proc.Natl.Acad.Sci.USA, 94, 1997
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1VRU
| HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES | 分子名称: | ALPHA-(2,6-DICHLOROPHENYL)-ALPHA-(2-ACETYL-5-METHYLANILINO)ACETAMIDE, HIV-1 REVERSE TRANSCRIPTASE | 著者 | Ren, J, Esnouf, R, Garman, E, Somers, D, Ross, C, Kirby, I, Keeling, J, Darby, G, Jones, Y, Stuart, D, Stammers, D. | 登録日 | 1995-04-19 | 公開日 | 1996-04-03 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | High resolution structures of HIV-1 RT from four RT-inhibitor complexes. Nat.Struct.Biol., 2, 1995
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1VRT
| HIGH RESOLUTION STRUCTURES OF HIV-1 RT FROM FOUR RT-INHIBITOR COMPLEXES | 分子名称: | 11-CYCLOPROPYL-5,11-DIHYDRO-4-METHYL-6H-DIPYRIDO[3,2-B:2',3'-E][1,4]DIAZEPIN-6-ONE, HIV-1 REVERSE TRANSCRIPTASE, MAGNESIUM ION | 著者 | Ren, J, Esnouf, R, Garman, E, Somers, D, Ross, C, Kirby, I, Keeling, J, Darby, G, Jones, Y, Stuart, D, Stammers, D. | 登録日 | 1995-04-19 | 公開日 | 1996-04-03 | 最終更新日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | High resolution structures of HIV-1 RT from four RT-inhibitor complexes. Nat.Struct.Biol., 2, 1995
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5DF8
| CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH CEFOPERAZONE | 分子名称: | (2R,4R,5R)-2-[(1R)-1-{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoethyl]-5-methyl-1,3-thiazinane-4-carboxylic acid, CHLORIDE ION, Cell division protein, ... | 著者 | Ren, J, Nettleship, J.E, Males, A, Stuart, D.I, Owens, R.J. | 登録日 | 2015-08-26 | 公開日 | 2016-01-13 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms. Febs Lett., 590, 2016
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5DF7
| CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 FROM PSEUDOMONAS AERUGINOSA IN COMPLEX WITH AZLOCILLIN | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-2-oxo-1-{[(2R)-2-{[(2-oxoimidazolidin-1-yl)carbonyl]amino}-2-phenylacetyl]amino}ethyl]-1,3-thiazolidine-4-carboxylic acid, CHLORIDE ION, Cell division protein, ... | 著者 | Ren, J, Nettleship, J.E, Males, A, Stuart, D.I, Owens, R.J. | 登録日 | 2015-08-26 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms. Febs Lett., 590, 2016
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5DF9
| CRYSTAL STRUCTURE OF PENICILLIN-BINDING PROTEIN 3 IN COMPLEX WITH DEACYLATED PRODUCT OF CEFOPERAZONE | 分子名称: | (2R,5R)-2-[(R)-carboxy{[(2R)-2-{[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino}-2-(4-hydroxyphenyl)acetyl]amino}methyl]-5-methyl-5,6-dihydro-2H-1,3-thiazine-4-carboxylic acid, Cell division protein, GLYCEROL, ... | 著者 | Ren, J, Nettleship, J.E, Males, A, Stuart, D.I, Owens, R.J. | 登録日 | 2015-08-26 | 公開日 | 2016-01-13 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal structures of penicillin-binding protein 3 in complexes with azlocillin and cefoperazone in both acylated and deacylated forms. Febs Lett., 590, 2016
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1RT7
| HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC84 | 分子名称: | 1-METHYL ETHYL 1-CHLORO-5-[[(5,6DIHYDRO-2-METHYL-1,4-OXATHIIN-3-YL)CARBONYL]AMINO]BENZOATE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | 著者 | Ren, J, Stammers, D.K, Stuart, D.I. | 登録日 | 1998-07-29 | 公開日 | 1999-07-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives. Biochemistry, 37, 1998
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1RT5
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1RT6
| HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC38 | 分子名称: | 1-METHYL ETHYL 2-CHLORO-5-[[[(1-METHYLETHOXY)THIOOXO]METHYL]AMINO]-BENZOATE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | 著者 | Ren, J, Stammers, D.K, Stuart, D.I. | 登録日 | 1998-07-29 | 公開日 | 1999-07-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives. Biochemistry, 37, 1998
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1RT4
| HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH UC781 | 分子名称: | 2-METHYL-FURAN-3-CARBOTHIOIC ACID [4-CHLORO-3-(3-METHYL-BUT-2-ENYLOXY)-PHENYL]-AMIDE, HIV-1 REVERSE TRANSCRIPTASE, PHOSPHATE ION | 著者 | Ren, J, Stammers, D.K, Stuart, D.I. | 登録日 | 1998-07-29 | 公開日 | 1999-07-29 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives. Biochemistry, 37, 1998
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1RT3
| AZT DRUG RESISTANT HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH 1051U91 | 分子名称: | 6,11-DIHYDRO-11-ETHYL-6-METHYL-9-NITRO-5H-PYRIDO[2,3-B][1,5]BENZODIAZEPIN-5-ONE, HIV-1 REVERSE TRANSCRIPTASE | 著者 | Ren, J, Stammers, D.K, Stuart, D.I. | 登録日 | 1998-06-29 | 公開日 | 1999-02-16 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | 3'-Azido-3'-deoxythymidine drug resistance mutations in HIV-1 reverse transcriptase can induce long range conformational changes. Proc.Natl.Acad.Sci.USA, 95, 1998
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4JGY
| Crystal structure of human coxsackievirus A16 uncoating intermediate (space group P4232) | 分子名称: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | 著者 | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, Mcauley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2013-03-04 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Picornavirus uncoating intermediate captured in atomic detail. Nat Commun, 4, 2013
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4JGZ
| Crystal structure of human coxsackievirus A16 uncoating intermediate (space group I222) | 分子名称: | Polyprotein, capsid protein VP1, capsid protein VP2, ... | 著者 | Ren, J, Wang, X, Hu, Z, Gao, Q, Sun, Y, Li, X, Porta, C, Walter, T.S, Gilbert, R.J, Zhao, Y, Axford, D, Williams, M, McAuley, K, Rowlands, D.J, Yin, W, Wang, J, Stuart, D.I, Rao, Z, Fry, E.E. | 登録日 | 2013-03-04 | 公開日 | 2013-06-05 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Picornavirus uncoating intermediate captured in atomic detail. Nat Commun, 4, 2013
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4I9Z
| Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 分子名称: | 5-bromo-2-{5-[(4-methylpiperazin-1-yl)acetyl]-2-propoxyphenyl}-6-(propan-2-yl)pyrimidin-4(3H)-one, DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, ... | 著者 | Ren, J, Chen, T, Xu, Y. | 登録日 | 2012-12-05 | 公開日 | 2014-01-01 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5. Bioorg.Med.Chem.Lett., 23, 2013
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4IA0
| Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors | 分子名称: | 5-bromo-2-{2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl}-6-octylpyrimidin-4(3H)-one, MAGNESIUM ION, ZINC ION, ... | 著者 | Ren, J, Chen, T, Xu, Y. | 登録日 | 2012-12-05 | 公開日 | 2014-01-01 | 実験手法 | X-RAY DIFFRACTION (2.17 Å) | 主引用文献 | Exploration of the 5-bromopyrimidin-4(3H)-ones as potent inhibitors of PDE5. Bioorg.Med.Chem.Lett., 23, 2013
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3KJJ
| Crystal structure of NMB1025, a member of YjgF protein family, from Neisseria meningitidis (hexagonal crystal form) | 分子名称: | GLYCEROL, NMB1025 protein | 著者 | Ren, J, Sainsbury, S, Owens, R.J, Oxford Protein Production Facility (OPPF) | 登録日 | 2009-11-03 | 公開日 | 2009-11-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal structure of NMB1025, a member of YjgF protein family, from Neisseria meningitidis To be Published
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1RT2
| CRYSTAL STRUCTURE OF HIV-1 REVERSE TRANSCRIPTASE COMPLEXED WITH TNK-651 | 分子名称: | 6-BENZYL-1-BENZYLOXYMETHYL-5-ISOPROPYL URACIL, HIV-1 REVERSE TRANSCRIPTASE | 著者 | Ren, J, Esnouf, R, Hopkins, A, Willcox, B, Jones, Y, Ross, C, Stammers, D, Stuart, D. | 登録日 | 1996-03-16 | 公開日 | 1997-04-21 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors. J.Med.Chem., 39, 1996
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3KJK
| Crystal structure of NMB1025, a member of YjgF protein family, from Neisseria meningitidis (monoclinic crystal form) | 分子名称: | NMB1025 protein | 著者 | Ren, J, Sainsbury, S, Owens, R.J, Oxford Protein Production Facility (OPPF) | 登録日 | 2009-11-03 | 公開日 | 2009-11-24 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Crystal structure of NMB1025, a member of YjgF protein family, from Neisseria meningitidis To be Published
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