4CWA
Structure of Plasmodium Falciparum Spermidine Synthase in Complex with 1H-Benzimidazole-2-pentanamine
Summary for 4CWA
| Entry DOI | 10.2210/pdb4cwa/pdb |
| Descriptor | SPERMIDINE SYNTHASE, 5-(1H-benzimidazol-2-yl)pentan-1-amine, 2-(2-{2-[2-(2-METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHANOL, ... (4 entities in total) |
| Functional Keywords | transferase, aminopropyl transferase, polyamine pathway, rossmann-like fold |
| Biological source | PLASMODIUM FALCIPARUM |
| Total number of polymer chains | 3 |
| Total formula weight | 97322.32 |
| Authors | Sprenger, J.,Halander, J.C.,Svensson, B.,Al-Karadaghi, S.,Persson, L. (deposition date: 2014-04-01, release date: 2014-10-08, Last modification date: 2023-12-20) |
| Primary citation | Sprenger, J.,Svensson, B.,Halander, J.,Carey, J.,Persson, L.,Al-Karadaghi, S. Three-Dimensional Structures of Plasmodium Falciparum Spermidine Synthase with Bound Inhibitors Suggest New Strategies for Drug Design. Acta Crystallogr.,Sect.D, 71:484-, 2015 Cited by PubMed: 25760598DOI: 10.1107/S1399004714027011 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.02 Å) |
Structure validation
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