Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 924 件
1K74
DownloadVisualize
BU of 1k74 by Molmil
The 2.3 Angstrom resolution crystal structure of the heterodimer of the human PPARgamma and RXRalpha ligand binding domains respectively bound with GW409544 and 9-cis retinoic acid and co-activator peptides.
分子名称: (9cis)-retinoic acid, 2-(1-METHYL-3-OXO-3-PHENYL-PROPYLAMINO)-3-{4-[2-(5-METHYL-2-PHENYL-OXAZOL-4-YL)-ETHOXY]-PHENYL}-PROPIONIC ACID, Peroxisome proliferator activated receptor gamma, ...
著者Xu, H.E, Lambert, M.H, Montana, V.G, Moore, L.B, Collins, J.L, Oplinger, J.A, Kliewer, S.A, Gampe Jr, R.T, McKee, D.D, Moore, J.T, Willson, T.M.
登録日2001-10-18
公開日2001-12-05
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural determinants of ligand binding selectivity between the peroxisome proliferator-activated receptors.
Proc.Natl.Acad.Sci.USA, 98, 2001
2E9A
DownloadVisualize
BU of 2e9a by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-628
分子名称: (1-HYDROXY-1-PHOSPHONO-2-[1,1';4',1'']TERPHENYL-3-YL-ETHYL)-PHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase
著者Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
1Q5V
DownloadVisualize
BU of 1q5v by Molmil
Apo-NikR
分子名称: Nickel responsive regulator
著者Schreiter, E.R, Sintchak, M.D, Guo, Y, Chivers, P.T, Sauer, R.T, Drennan, C.L.
登録日2003-08-11
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Nickel-Responsive Transcription Factor NikR
Nat.Struct.Biol., 10, 2003
1KE8
DownloadVisualize
BU of 1ke8 by Molmil
CYCLIN-DEPENDENT KINASE 2 (CDK2) COMPLEXED WITH 4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE
分子名称: 4-{[(2-OXO-1,2-DIHYDRO-3H-INDOL-3-YLIDENE)METHYL]AMINO}-N-(1,3-THIAZOL-2-YL)BENZENESULFONAMIDE, CELL DIVISION PROTEIN KINASE 2
著者Bramson, H.N, Corona, J, Davis, S.T, Dickerson, S.H, Edelstein, M, Frye, S.V, Gampe, R.T, Hassell, A.M, Shewchuk, L.M, Kuyper, L.F.
登録日2001-11-14
公開日2002-05-14
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Oxindole-based inhibitors of cyclin-dependent kinase 2 (CDK2): design, synthesis, enzymatic activities, and X-ray crystallographic analysis.
J.Med.Chem., 44, 2001
1Q5Y
DownloadVisualize
BU of 1q5y by Molmil
Nickel-Bound C-terminal Regulatory Domain of NikR
分子名称: 1,2-ETHANEDIOL, NICKEL (II) ION, Nickel responsive regulator
著者Schreiter, E.R, Sintchak, M.D, Guo, Y, Chivers, P.T, Sauer, R.T, Drennan, C.L.
登録日2003-08-11
公開日2003-09-30
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal Structure of the Nickel-Responsive Transcription Factor NikR
Nat.Struct.Biol., 10, 2003
2CKH
DownloadVisualize
BU of 2ckh by Molmil
SENP1-SUMO2 complex
分子名称: SENTRIN-SPECIFIC PROTEASE 1, SMALL UBIQUITIN-RELATED MODIFIER 2
著者Shen, L.N, Dong, C, Liu, H, Hay, R.T, Naismith, J.H.
登録日2006-04-18
公開日2006-04-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献The Structure of Senp1-Sumo-2 Complex Suggests a Structural Basis for Discrimination between Sumo Paralogues During Processing.
Biochem.J., 397, 2006
2BB8
DownloadVisualize
BU of 2bb8 by Molmil
N-TERMINAL DNA BINDING DOMAIN FROM TN916 INTEGRASE, NMR, MINIMIZED AVERAGE STRUCTURE
分子名称: INTEGRASE
著者Clubb, R.T, Connolly, K.M, Wojciak, J.M.
登録日1998-05-12
公開日1998-11-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Site-specific DNA binding using a variation of the double stranded RNA binding motif.
Nat.Struct.Biol., 5, 1998
1LI4
DownloadVisualize
BU of 1li4 by Molmil
Human S-adenosylhomocysteine hydrolase complexed with neplanocin
分子名称: 3-(6-AMINO-PURIN-9-YL)-5-HYDROXYMETHYL-CYCLOPENTANE-1,2-DIOL, ISOPROPYL ALCOHOL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
著者Yang, X, Hu, Y, Yin, D.H, Turner, M.A, Wang, M, Borchardt, R.T, Howell, P.L, Kuczera, K, Schowen, R.L.
登録日2002-04-17
公開日2003-05-20
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Catalytic strategy of S-adenosyl-L-homocysteine hydrolase: Transition-state stabilization and the avoidance of abortive reactions
Biochemistry, 42, 2003
2E94
DownloadVisualize
BU of 2e94 by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-364
分子名称: 3-BIPHENYL-3-YL-1-(2-HYDROXY-2,2-DIPHOSPHONOETHYL)PYRIDINIUM, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Guo, R.T, Ko, T.P, Cao, R, Chen, C.K.-M, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E95
DownloadVisualize
BU of 2e95 by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-675
分子名称: 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID, Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Guo, R.T, Cao, R, Ko, T.P, Jeng, W.Y, Chang, T.H, Chen, C.K.-M, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E1R
DownloadVisualize
BU of 2e1r by Molmil
Structure of eEF2 in complex with a sordarin derivative
分子名称: (1S,4S,5S,6R,9S,11S)-6-CHLORO-9-FORMYL-13-ISOPROPYL-5-METHYL-2-({[(3AR,5R,7R ,7AS)-7-METHYL-3-METHYLENEHEXAHYDRO-2H-FURO[2,3-C]PYRAN-5-YL]OXY}METHYL)TETR ACYCLO[7.4.0.02,11.04,8]TRIDEC-12-ENE-1-CARBOXYLIC ACI, Elongation factor 2, GUANOSINE-5'-DIPHOSPHATE
著者Soe, R, Mosley, R.T, Andersen, G.R.
登録日2006-10-27
公開日2006-11-14
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Sordarin derivatives induce a novel conformation of the yeast ribosome translocation factor eEF2
J.Biol.Chem., 282, 2007
2EET
DownloadVisualize
BU of 2eet by Molmil
Guanine Riboswitch A21G, U75C mutant bound to hypoxanthine
分子名称: ACETATE ION, COBALT HEXAMMINE(III), Guanine Riboswitch, ...
著者Gilbert, S.D, Edwards, A.L, Batey, R.T.
登録日2007-02-18
公開日2007-11-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mutational analysis of the purine riboswitch aptamer domain
Biochemistry, 46, 2007
2E9C
DownloadVisualize
BU of 2e9c by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-675
分子名称: 1-HYDROXY-2-[3'-(NAPHTHALENE-2-SULFONYLAMINO)-BIPHENYL-3-YL]ETHYLIDENE-1,1-BISPHOSPHONIC ACID, Undecaprenyl pyrophosphate synthetase
著者Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2Z4Y
DownloadVisualize
BU of 2z4y by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-252
分子名称: (1-HYDROXYNONANE-1,1-DIYL)BIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J.
登録日2007-06-26
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation
J.Med.Chem., 51, 2008
2B57
DownloadVisualize
BU of 2b57 by Molmil
Guanine Riboswitch C74U mutant bound to 2,6-diaminopurine
分子名称: 65-MER, 9H-PURINE-2,6-DIAMINE, ACETATE ION, ...
著者Gilbert, S.D, Stoddard, C.D, Wise, S.J, Batey, R.T.
登録日2005-09-27
公開日2006-05-23
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Thermodynamic and kinetic characterization of ligand binding to the purine riboswitch aptamer domain.
J.Mol.Biol., 359, 2006
2AVU
DownloadVisualize
BU of 2avu by Molmil
Structure of the Escherichia coli FlhDC complex, a prokaryotic heteromeric regulator of transcription
分子名称: Flagellar transcriptional activator flhC, Transcriptional activator flhD, ZINC ION
著者Wang, S, Fleming, R.T, Westbrook, E.M, Matsumura, P, McKay, D.B.
登録日2005-08-30
公開日2005-12-13
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the Escherichia coli FlhDC Complex, a Prokaryotic Heteromeric Regulator of Transcription.
J.Mol.Biol., 355, 2006
2ALE
DownloadVisualize
BU of 2ale by Molmil
Crystal structure of yeast RNA splicing factor Snu13p
分子名称: MAGNESIUM ION, NHP2/L7aE family protein YEL026W
著者Dobbyn, H.C, McEwan, P.A, Bella, J, O'Keefe, R.T.
登録日2005-08-05
公開日2006-10-03
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Analysis of pre-mRNA and pre-rRNA processing factor Snu13p structure and mutants.
Biochem.Biophys.Res.Commun., 360, 2007
2AO6
DownloadVisualize
BU of 2ao6 by Molmil
Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753 peptide and R1881
分子名称: (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, 14-mer fragment of Nuclear receptor coactivator 2, androgen receptor
著者He, B, Gampe Jr, R.T, Kole, A.J, Hnat, A.T, Stanley, T.B, An, G, Stewart, E.L, Kalman, R.I, Minges, J.T, Wilson, E.M.
登録日2005-08-12
公開日2005-08-30
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance
Mol.Cell, 16, 2004
2CME
DownloadVisualize
BU of 2cme by Molmil
The crystal structure of SARS coronavirus ORF-9b protein
分子名称: DECANE, HYPOTHETICAL PROTEIN 5
著者Meier, C, Aricescu, A.R, Assenberg, R, Aplin, R.T, Gilbert, R.J.C, Grimes, J.M, Stuart, D.I.
登録日2006-05-06
公開日2006-07-19
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Crystal Structure of Orf-9B, a Lipid Binding Protein from the Sars Coronavirus.
Structure, 14, 2006
2D2R
DownloadVisualize
BU of 2d2r by Molmil
Crystal structure of Helicobacter pylori Undecaprenyl Pyrophosphate Synthase
分子名称: Undecaprenyl Pyrophosphate Synthase
著者Kuo, C.J, Guo, R.T, Chen, C.L, Ko, T.P, Cheng, Y.S, Cheng, Y.L, Liang, P.H, Wang, A.H.-J.
登録日2005-09-16
公開日2006-09-26
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Structure-based inhibitors exhibit differential activities against Helicobacter pylori and Escherichia coli undecaprenyl pyrophosphate synthases.
J.Biomed.Biotechnol., 2008, 2008
2Z4Z
DownloadVisualize
BU of 2z4z by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and BPH-sc01
分子名称: (6E,11E)-HEPTADECA-6,11-DIENE-9,9-DIYLBIS(PHOSPHONIC ACID), Geranylgeranyl pyrophosphate synthetase, MAGNESIUM ION
著者Chen, C.K.-M, Guo, R.T, Hudock, M, Cao, R, Oldfield, E, Wang, A.H.-J.
登録日2007-06-26
公開日2008-07-01
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation
J.Med.Chem., 51, 2008
2E9D
DownloadVisualize
BU of 2e9d by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-676
分子名称: Undecaprenyl pyrophosphate synthetase, [1-HYDROXY-2-(1,1':3',1''-TERPHENYL-3-YLOXY)ETHANE-1,1-DIYL]BIS(PHOSPHONIC ACID)
著者Guo, R.T, Cao, R, Ko, T.P, Liang, P.H, Oldfield, E, Wang, A.H.J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2EEU
DownloadVisualize
BU of 2eeu by Molmil
Guanine riboswitch U22A, A52U mutant bound to hypoxanthine
分子名称: ACETATE ION, COBALT HEXAMMINE(III), Guanine riboswitch, ...
著者Gilbert, S.D, Love, C.E, Batey, R.T.
登録日2007-02-19
公開日2007-11-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Mutational analysis of the purine riboswitch aptamer domain
Biochemistry, 46, 2007
2E98
DownloadVisualize
BU of 2e98 by Molmil
E. coli undecaprenyl pyrophosphate synthase in complex with BPH-629
分子名称: Undecaprenyl pyrophosphate synthetase, [2-(3-DIBENZOFURAN-4-YL-PHENYL)-1-HYDROXY-1-PHOSPHONO-ETHYL]-PHOSPHONIC ACID
著者Guo, R.T, Ko, T.P, Cao, R, Liang, P.H, Oldfield, E, Wang, A.H.J.
登録日2007-01-24
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007
2E8V
DownloadVisualize
BU of 2e8v by Molmil
S. cerevisiae geranylgeranyl pyrophosphate synthase in complex with product GGPP (P21)
分子名称: GERANYLGERANYL DIPHOSPHATE, Geranylgeranyl pyrophosphate synthetase
著者Chen, C.K.-M, Guo, R.T, Ko, T.P, Jeng, W.Y, Chang, T.H, Liang, P.H, Oldfield, E, Wang, A.H.-J.
登録日2007-01-23
公開日2007-06-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases
Proc.Natl.Acad.Sci.Usa, 104, 2007

226707

件を2024-10-30に公開中

PDB statisticsPDBj update infoContact PDBjnumon