2BZX
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3PUF
| Crystal structure of human RNase H2 complex | Descriptor: | Ribonuclease H2 subunit A, Ribonuclease H2 subunit B, Ribonuclease H2 subunit C | Authors: | Figiel, M, Chon, H, Cerritelli, S.M, Cybulska, M, Crouch, R.J, Nowotny, M. | Deposit date: | 2010-12-04 | Release date: | 2010-12-22 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | The structural and biochemical characterization of human RNase H2 complex reveals the molecular basis for substrate recognition and Aicardi-Goutieres syndrome defects. J.Biol.Chem., 286, 2011
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5UFC
| Crystal Structure of Variable Lymphocyte Receptor (VLR) Tn4-22 with H-trisaccharide bound | Descriptor: | Tn4-22, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | Authors: | Collins, B.C, Gunn, R.J, McKitrick, T.R, Cummings, R.D, Cooper, M.D, Herrin, B.R, Wilson, I.A. | Deposit date: | 2017-01-04 | Release date: | 2017-10-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.888 Å) | Cite: | Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates. Structure, 25, 2017
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5CMI
| GTA mutant without mercury - E303D | Descriptor: | Histo-blood group ABO system transferase | Authors: | Gagnon, S.M.L, Blackler, R.J. | Deposit date: | 2015-07-16 | Release date: | 2016-07-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site. Glycobiology, 27, 2017
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2J92
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5UDM
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2CO7
| Salmonella enterica SafA pilin in complex with the SafB chaperone (Type II) | Descriptor: | PUTATIVE FIMBRIAE ASSEMBLY CHAPERONE, SAFA PILUS SUBUNIT, SULFATE ION | Authors: | Remaut, H, Rose, R.J, Hannan, T.J, Hultgren, S.J, Radford, S.E, Ashcroft, A.E, Waksman, G. | Deposit date: | 2006-05-25 | Release date: | 2006-06-27 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Donor-Strand Exchange in Chaperone-Assisted Pilus Assembly Proceeds Through a Concerted Beta-Strand Displacement Mechanism Mol.Cell, 22, 2006
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3PZ0
| The crystal structure of AaLeuRS-CP1 | Descriptor: | CALCIUM ION, Leucyl-tRNA synthetase subunit alpha | Authors: | Liu, R.J, Wang, E.D. | Deposit date: | 2010-12-13 | Release date: | 2011-08-24 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase Biochem.J., 440, 2011
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3PZT
| Structure of the endo-1,4-beta-glucanase from Bacillus subtilis 168 with manganese(II) ion | Descriptor: | Endoglucanase, GLYCEROL, MANGANESE (II) ION, ... | Authors: | Santos, C.R, Paiva, J.H, Akao, P.K, Meza, A.N, Silva, J.C, Squina, F.M, Ward, R.J, Ruller, R, Murakami, M.T. | Deposit date: | 2010-12-14 | Release date: | 2011-09-14 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168. Biochem.J., 441, 2012
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1X7J
| CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH GENISTEIN | Descriptor: | Estrogen receptor beta, GENISTEIN, STEROID RECEPTOR COACTIVATOR-1 | Authors: | Manas, E.S, Xu, Z.B, Unwalla, R.J, Somers, W.S. | Deposit date: | 2004-08-14 | Release date: | 2005-03-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Understanding the Selectivity of Genistein for Human Estrogen Receptor-Beta Using X-Ray Crystallography and Computational Methods Structure, 12, 2004
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5UE5
| proMMP-7 with heparin octasaccharide bound to the catalytic domain | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, Matrilysin, ... | Authors: | Fulcher, Y.G, Prior, S.H, Linhardt, R.J, Van Doren, S.R. | Deposit date: | 2016-12-29 | Release date: | 2017-07-19 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7. Structure, 25, 2017
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5CMF
| GTA mutant with mercury - E303A | Descriptor: | Histo-blood group ABO system transferase, MERCURY (II) ION | Authors: | Gagnon, S.M.L, Blackler, R.J. | Deposit date: | 2015-07-16 | Release date: | 2016-07-20 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Glycosyltransfer in mutants of putative catalytic residue Glu303 of the human ABO(H) A and B blood group glycosyltransferases GTA and GTB proceeds through a labile active site. Glycobiology, 27, 2017
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5UHY
| A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection | Descriptor: | ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein | Authors: | Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G. | Deposit date: | 2017-01-12 | Release date: | 2017-03-29 | Last modified: | 2019-11-27 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | A human antibody against Zika virus crosslinks the E protein to prevent infection. Nat Commun, 8, 2017
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1X7R
| CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR ALPHA COMPLEXED WITH GENISTEIN | Descriptor: | Estrogen receptor 1 (alpha), GENISTEIN, steroid receptor coactivator-3 | Authors: | Manas, E.S, Xu, Z.B, Unwalla, R.J, Somers, W.S. | Deposit date: | 2004-08-16 | Release date: | 2005-03-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Understanding the Selectivity of Genistein for Human Estrogen Receptor-Beta Using X-Ray Crystallography and Computational Methods Structure, 12, 2004
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6BAU
| Crystal Structure of GltPh R397C in complex with L-Cysteine | Descriptor: | CYSTEINE, Glutamate transporter homolog, SODIUM ION | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | Deposit date: | 2017-10-15 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.8 Å) | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Nat Commun, 9, 2018
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5UE2
| proMMP-7 with heparin octasaccharide bridging between domains | Descriptor: | 2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-2-O-sulfo-alpha-L-idopyranuronic acid-(1-4)-2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose, CALCIUM ION, Matrilysin, ... | Authors: | Fulcher, Y.G, Prior, S.H, Linhardt, R.J, Van Doren, S.R. | Deposit date: | 2016-12-29 | Release date: | 2017-07-19 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Glycan Activation of a Sheddase: Electrostatic Recognition between Heparin and proMMP-7. Structure, 25, 2017
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1PFC
| MOLECULAR-REPLACEMENT STRUCTURE OF GUINEA PIG IGG1 P*FC(PRIME) REFINED AT 3.1 ANGSTROMS RESOLUTION | Descriptor: | IGG1 PFC' FC | Authors: | Bryant, S.H, Amzel, L.M, Poljak, R.J, Phizackerley, R.P. | Deposit date: | 1981-10-28 | Release date: | 1982-02-03 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (3.125 Å) | Cite: | Molecular-Replacement Structure of Guinea Pig Igg1 Pfc(Prime) Refined at 3.1 Angstroms Resolution Acta Crystallogr.,Sect.B, 41, 1985
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5C1Z
| Parkin (UblR0RBR) | Descriptor: | CHLORIDE ION, E3 ubiquitin-protein ligase parkin, GLYCEROL, ... | Authors: | kumar, A, Aguirre, J.D, Condos, T.E.C, Martinez-Torres, R.J, Chaugule, V.K, Toth, R, Sundaramoorthy, R, Mercier, P, Knebel, A, Spratt, D.E, Barber, K.R, Shaw, G.S, Walden, H. | Deposit date: | 2015-06-15 | Release date: | 2015-07-29 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Disruption of the autoinhibited state primes the E3 ligase parkin for activation and catalysis. Embo J., 34, 2015
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3QEE
| The structure and function of an arabinan-specific alpha-1,2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases | Descriptor: | ACETATE ION, Beta-xylosidase/alpha-L-arabinfuranosidase, gly43N, ... | Authors: | Cartmell, A, Mckee, L.S, Pena, M, Larsbrink, J, Brumer, H, Lewis, R.J, Viks-Nielsen, A, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-01-20 | Release date: | 2011-02-16 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The Structure and Function of an Arabinan-specific {alpha}-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases. J.Biol.Chem., 286, 2011
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1X78
| CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH WAY-244 | Descriptor: | Estrogen receptor beta, STEROID RECEPTOR COACTIVATOR-1, [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE | Authors: | Manas, E.S, Unwalla, R.J, Xu, Z.B, Malamas, M.S, Miller, C.P, Harris, H.A, Hsiao, C, Akopian, T, Hum, W.T, Malakian, K, Wolfrom, S, Bapat, A, Bhat, R.A, Stahl, M.L, Somers, W.S, Alvarez, J.C. | Deposit date: | 2004-08-13 | Release date: | 2005-03-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure-Based Design of Estrogen Receptor-Beta Selective Ligands J.Am.Chem.Soc., 126, 2004
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5COJ
| Structure of Hydroxyethylthiazole kinase ThiM from Staphylococcus aureus in complex with native substrate 2-(4-methyl-1,3-thiazol-5-yl)ethanol. | Descriptor: | 2-(4-METHYL-THIAZOL-5-YL)-ETHANOL, Hydroxyethylthiazole kinase, MAGNESIUM ION | Authors: | Drebes, J, Kuenz, M, Eberle, R.J, Oberthuer, D, Cang, H, Wrenger, C, Betzel, C. | Deposit date: | 2015-07-20 | Release date: | 2016-03-23 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections. Sci Rep, 6, 2016
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1NQH
| OUTER MEMBRANE COBALAMIN TRANSPORTER (BTUB) FROM E. COLI, WITH BOUND CALCIUM AND CYANOCOBALAMIN (VITAMIN B12) SUBSTRATE | Descriptor: | (HYDROXYETHYLOXY)TRI(ETHYLOXY)OCTANE, CALCIUM ION, CYANOCOBALAMIN, ... | Authors: | Chimento, D.P, Mohanty, A.K, Kadner, R.J, Wiener, M.C. | Deposit date: | 2003-01-21 | Release date: | 2003-04-29 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Substrate-induced transmembrane signaling in the cobalamin transporter BtuB Nat.Struct.Biol., 10, 2003
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3QED
| The structure and function of an arabinan-specific alpha-1,2-arabinofuranosidase identified from screening the activities of bacterial GH43 glycoside hydrolases | Descriptor: | Beta-xylosidase/alpha-L-arabinfuranosidase, gly43N, CALCIUM ION, ... | Authors: | Cartmell, A, Mckee, L.S, Pena, M, Larsbrink, J, Brumer, H, Lewis, R.J, Viks-Nielsen, A, Gilbert, H.J, Marles-Wright, J. | Deposit date: | 2011-01-20 | Release date: | 2011-02-16 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The Structure and Function of an Arabinan-specific {alpha}-1,2-Arabinofuranosidase Identified from Screening the Activities of Bacterial GH43 Glycoside Hydrolases. J.Biol.Chem., 286, 2011
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6BAT
| Crystal Structure of Wild-Type GltPh in complex with L-aspartate | Descriptor: | ASPARTIC ACID, Glutamate transporter homolog, SODIUM ION | Authors: | Font, J, Scopelliti, A.J, Vandenberg, R.J, Boudker, O, Ryan, R.M. | Deposit date: | 2017-10-15 | Release date: | 2018-01-17 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Structural characterisation reveals insights into substrate recognition by the glutamine transporter ASCT2/SLC1A5. Nat Commun, 9, 2018
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5CM5
| Structure of Hydroxyethylthiazole Kinase ThiM from Staphylococcus aureus | Descriptor: | Hydroxyethylthiazole kinase | Authors: | Drebes, J, Kuenz, M, Eberle, R.J, Oberthuer, D, Cang, H, Wrenger, C, Betzel, C. | Deposit date: | 2015-07-16 | Release date: | 2016-03-23 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | Structure of ThiM from Vitamin B1 biosynthetic pathway of Staphylococcus aureus - Insights into a novel pro-drug approach addressing MRSA infections. Sci Rep, 6, 2016
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