3NL0
 
 | | Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase | | 分子名称: | 3D polymerase, 5'-R(*G*GP*GP*CP*CP*C)-3', 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', ... | | 著者 | Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E. | | 登録日 | 2010-06-21 | | 公開日 | 2011-07-13 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
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5IYB
 | | Human core-PIC in the open state | | 分子名称: | DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase II subunit RPB10, DNA-directed RNA polymerase II subunit RPB11-a, ... | | 著者 | He, Y, Yan, C, Fang, J, Inouye, C, Tjian, R, Ivanov, I, Nogales, E. | | 登録日 | 2016-03-24 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Near-atomic resolution visualization of human transcription promoter opening.
Nature, 533, 2016
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7XXF
 | | Structure of photosynthetic LH1-RC super-complex of Rhodopila globiformis | | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (6~{E},8~{E},10~{E},12~{E},14~{E},16~{E},18~{E},20~{E},22~{E},24~{E},26~{E},28~{E})-2,31-dimethoxy-2,6,10,14,19,23,27,31-octamethyl-dotriaconta-6,8,10,12,14,16,18,20,22,24,26,28-dodecaen-5-one, 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, ... | | 著者 | Tani, K, Kanno, R, Kurosawa, K, Takaichi, S, Nagashima, K.V.P, Hall, M, Yu, L.-J, Kimura, Y, Madigan, M.T, Mizoguchi, A, Humbel, B.M, Wang-Otomo, Z.-Y. | | 登録日 | 2022-05-30 | | 公開日 | 2022-11-16 | | 最終更新日 | 2022-11-23 | | 実験手法 | ELECTRON MICROSCOPY (2.24 Å) | | 主引用文献 | An LH1-RC photocomplex from an extremophilic phototroph provides insight into origins of two photosynthesis proteins.
Commun Biol, 5, 2022
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4GOS
 | | Crystal structure of human B7-H4 IgV-like domain | | 分子名称: | V-set domain-containing T-cell activation inhibitor 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | | 著者 | Vigdorovich, V, Ramagopal, U, Bhosle, R, Toro, R, Nathenson, S.G, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Atoms-to-Animals: The Immune Function Network (IFN) | | 登録日 | 2012-08-20 | | 公開日 | 2012-09-12 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.59 Å) | | 主引用文献 | Structure and cancer immunotherapy of the B7 family member B7x.
Cell Rep, 9, 2014
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4GP1
 | | Crystal structure of ISOPRENOID SYNTHASE A3MSH1 (TARGET EFI-501992) from pyrobaculum calidifontis complexed with DMAPP | | 分子名称: | CHLORIDE ION, DIMETHYLALLYL DIPHOSPHATE, Polyprenyl synthetase, ... | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Poulter, C.D, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-08-20 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Crystal Structure of Isoprenoid Synthase from Pyrobaculum Calidifontis
To be Published
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4H1Z
 | | Crystal structure of putative isomerase from Sinorhizobium meliloti, open loop conformation (target EFI-502104) | | 分子名称: | CHLORIDE ION, Enolase Q92Zs5, FORMIC ACID, ... | | 著者 | Patskovsky, Y, Toro, R, Bhosle, R, Hillerich, B, Seidel, R.D, Washington, E, Scott Glenn, A, Chowdhury, S, Evans, B, Hammonds, J, Zencheck, W.D, Imker, H.J, Gerlt, J.A, Almo, S.C, Enzyme Function Initiative (EFI) | | 登録日 | 2012-09-11 | | 公開日 | 2012-09-26 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.012 Å) | | 主引用文献 | Crystal Structure of Enolase Q92Zs5 (Target EFI-502104) from Sinorhizobium meliloti
To be Published
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6W0O
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5JAA
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6W08
 | | Crystal Structure of Motility Associated Killing Factor E from Vibrio cholerae | | 分子名称: | 1,2-ETHANEDIOL, ACETIC ACID, CHLORIDE ION, ... | | 著者 | Kim, Y, Jedrzejczak, R, Joachimiak, G, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-02-29 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins.
J.Bacteriol., 204, 2022
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6W01
 | | The 1.9 A Crystal Structure of NSP15 Endoribonuclease from SARS CoV-2 in the Complex with a Citrate | | 分子名称: | 1,2-ETHANEDIOL, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kim, Y, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-02-28 | | 公開日 | 2020-03-11 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of Nsp15 endoribonuclease NendoU from SARS-CoV-2.
Protein Sci., 29, 2020
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5JFB
 | | Crystal structure of the scavenger receptor cysteine-rich domain 5 (SRCR5) from porcine CD163 | | 分子名称: | Scavenger receptor cysteine-rich type 1 protein M130 | | 著者 | Ma, H, Jiang, L, Qiao, S, Zhang, G, Li, R. | | 登録日 | 2016-04-19 | | 公開日 | 2017-03-22 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Crystal Structure of the Fifth Scavenger Receptor Cysteine-Rich Domain of Porcine CD163 Reveals an Important Residue Involved in Porcine Reproductive and Respiratory Syndrome Virus Infection
J. Virol., 91, 2017
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6W1W
 | | Crystal Structure of Motility Associated Killing Factor B from Vibrio cholerae | | 分子名称: | 1,2-ETHANEDIOL, motility-associated killing factor MakB | | 著者 | Kim, Y, Welk, L, Jedrzejczak, R, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-03-04 | | 公開日 | 2020-03-25 | | 最終更新日 | 2022-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | | 主引用文献 | A Genomic Island of Vibrio cholerae Encodes a Three-Component Cytotoxin with Monomer and Protomer Forms Structurally Similar to Alpha-Pore-Forming Toxins.
J.Bacteriol., 204, 2022
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6VYO
 | | Crystal structure of RNA binding domain of nucleocapsid phosphoprotein from SARS coronavirus 2 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, CHLORIDE ION, GLYCEROL, ... | | 著者 | Chang, C, Michalska, K, Jedrzejczak, R, Maltseva, N, Endres, M, Godzik, A, Kim, Y, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-02-27 | | 公開日 | 2020-03-11 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Epitopes recognition of SARS-CoV-2 nucleocapsid RNA binding domain by human monoclonal antibodies.
Iscience, 27, 2024
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5JH1
 | | Crystal structure of the apo form of AKR4C7 from maize | | 分子名称: | Aldose reductase, AKR4C7 | | 著者 | Giuseppe, P.O, Santos, M.L, Sousa, S.M, Koch, K.E, Yunes, J.A, Aparicio, R, Murakami, M.T. | | 登録日 | 2016-04-20 | | 公開日 | 2016-11-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | | 主引用文献 | A comparative structural analysis reveals distinctive features of co-factor binding and substrate specificity in plant aldo-keto reductases.
Biochem.Biophys.Res.Commun., 474, 2016
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5JJB
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5JMD
 | | Heparinase III-BT4657 gene product, Methylated Lysines | | 分子名称: | Heparinase III protein, MAGNESIUM ION | | 著者 | Ulaganathan, T.S, Shi, R, Yao, D, Garron, M.-L, Cherney, M, Cygler, M. | | 登録日 | 2016-04-28 | | 公開日 | 2016-05-25 | | 最終更新日 | 2018-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Conformational flexibility of PL12 family heparinases: structure and substrate specificity of heparinase III from Bacteroides thetaiotaomicron (BT4657).
Glycobiology, 27, 2017
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6X4S
 | | MCU-EMRE complex of a metazoan mitochondrial calcium uniporter | | 分子名称: | CALCIUM ION, Calcium uniporter protein,Protein EMRE homolog, mitochondrial-like Protein fusion | | 著者 | Long, S.B, Wang, C, Baradaran, R. | | 登録日 | 2020-05-22 | | 公開日 | 2020-09-02 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Structure and Reconstitution of an MCU-EMRE Mitochondrial Ca 2+ Uniporter Complex.
J.Mol.Biol., 432, 2020
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1A0C
 | | XYLOSE ISOMERASE FROM THERMOANAEROBACTERIUM THERMOSULFURIGENES | | 分子名称: | COBALT (II) ION, XYLOSE ISOMERASE | | 著者 | Gallay, O, Chopra, R, Conti, E, Brick, P, Blow, D. | | 登録日 | 1997-11-28 | | 公開日 | 1998-06-03 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal Structures of Class II Xylose Isomerases from Two Thermophiles and a Hyperthermophile
To be Published
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6WRH
 | | The crystal structure of Papain-Like Protease of SARS CoV-2 , C111S mutant | | 分子名称: | CHLORIDE ION, GLYCEROL, Non-structural protein 3, ... | | 著者 | Osipiuk, J, Tesar, C, Jedrzejczak, R, Endres, M, Welk, L, Babnigg, G, Kim, Y, Michalska, K, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-04-29 | | 公開日 | 2020-05-06 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of papain-like protease from SARS-CoV-2 and its complexes with non-covalent inhibitors.
Nat Commun, 12, 2021
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5L5N
 | | Plexin A4 full extracellular region, domains 1 to 7 modeled, data to 8.5 angstrom, spacegroup P4(3)22 | | 分子名称: | Plexin-A4 | | 著者 | Janssen, B.J.C, Kong, Y, Malinauskas, T, Vangoor, V.R, Coles, C.H, Kaufmann, R, Ni, T, Gilbert, R.J.C, Padilla-Parra, S, Pasterkamp, R.J, Jones, E.Y. | | 登録日 | 2016-05-28 | | 公開日 | 2016-07-06 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (8.502 Å) | | 主引用文献 | Structural Basis for Plexin Activation and Regulation.
Neuron, 91, 2016
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5KQY
 | | Protease E35D-DRV | | 分子名称: | (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease E35D-DRV | | 著者 | Liu, Z, Poole, K.M, Mahon, B.P, McKenna, R, Fanucci, G.E. | | 登録日 | 2016-07-06 | | 公開日 | 2016-09-21 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Effects of Hinge-region Natural Polymorphisms on Human Immunodeficiency Virus-Type 1 Protease Structure, Dynamics, and Drug Pressure Evolution.
J.Biol.Chem., 291, 2016
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5L7O
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5L8J
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5KSQ
 | | Stationary phase survival protein E (SurE) from Xylella fastidiosa | | 分子名称: | 5'-nucleotidase SurE, IODIDE ION, MANGANESE (II) ION, ... | | 著者 | Machado, A.T.P, Fonseca, E.M.B, Dos Reis, M.A, Saraiva, A.M, Dos Santos, C.A, De Toledo, M.A, Polikarpov, I, De Souza, A.P, Aparicio, R, Iulek, J. | | 登録日 | 2016-07-09 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (2.63 Å) | | 主引用文献 | Conformational variability of the stationary phase survival protein E from Xylella fastidiosa revealed by X-ray crystallography, small-angle X-ray scattering studies, and normal mode analysis.
Proteins, 85, 2017
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1UNJ
 | | Crystal structure of a 7-Aminoactinomycin D complex with non-complementary DNA | | 分子名称: | 5'-D(*TP*TP*AP*GP*BRU*TP)-3', 7-AMINO-ACTINOMYCIN D | | 著者 | Alexopoulos, E.C, Klement, R, Jares-Erijman, E.A, Uson, I, Jovin, T.M, Sheldrick, G.M. | | 登録日 | 2003-09-10 | | 公開日 | 2004-12-16 | | 最終更新日 | 2024-07-10 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal and Solution Structures of 7-Amino-Actinomycin D Complexes with D(Ttagbrut), D(Ttagtt) and D(Tttagttt)
Acta Crystallogr.,Sect.D, 61, 2005
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