6W0O
Amyloid-beta(1-40) fibril derived from Alzheimer's disease cortical tissue
Summary for 6W0O
| Entry DOI | 10.2210/pdb6w0o/pdb |
| EMDB information | 21501 |
| NMR Information | BMRB: 30731 |
| Descriptor | Amyloid-beta precursor protein (1 entity in total) |
| Functional Keywords | amyloid-beta, alzheimer's disease, protein fibril |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 6 |
| Total formula weight | 26015.11 |
| Authors | Ghosh, U.,Thurber, K.R.,Tycko, R. (deposition date: 2020-03-02, release date: 2021-01-13, Last modification date: 2023-06-14) |
| Primary citation | Ghosh, U.,Thurber, K.R.,Yau, W.M.,Tycko, R. Molecular structure of a prevalent amyloid-beta fibril polymorph from Alzheimer's disease brain tissue. Proc.Natl.Acad.Sci.USA, 118:-, 2021 Cited by PubMed: 33431654DOI: 10.1073/pnas.2023089118 PDB entries with the same primary citation |
| Experimental method | ELECTRON MICROSCOPY (2.77 Å) SOLID-STATE NMR (2.77 Å) |
Structure validation
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