1UNJ

Crystal structure of a 7-Aminoactinomycin D complex with non-complementary DNA

Summary for 1UNJ

Related1A7Z 209D 1UNM 1I3W 1A7Y 1FJA 173D 2D55 1DSC 1L1V 316D 1DSD 1MNV 1OVF 1QFI
Related PRD IDPRD_000010
Descriptor5'-D(*TP*TP*AP*GP*BRU*TP)-3', 7-AMINO-ACTINOMYCIN D (3 entities in total)
Functional Keywordsactinomycin d, actinomycin, antibiotic, anti cancer, antitumor, chromophore, depsipeptide, dna-antibiotic complex, fluorescent agent, hoogsten base-pair, dna/antibiotic
Biological sourceSTREPTOMYCES ANTIBIOTICUS
Total number of polymer chains24
Total molecular weight40261.23
Authors
Alexopoulos, E.C.,Klement, R.,Jares-Erijman, E.A.,Uson, I.,Jovin, T.M.,Sheldrick, G.M. (deposition date: 2003-09-10, release date: 2004-12-16, Last modification date: 2019-03-06)
Primary citation
Alexopoulos, E.C.,Jares-Erijman, E.A.,Jovin, T.M.,Klement, R.,Machinek, R.,Sheldrick, G.M.,Uson, I.
Crystal and Solution Structures of 7-Amino-Actinomycin D Complexes with D(Ttagbrut), D(Ttagtt) and D(Tttagttt)
Acta Crystallogr.,Sect.D, 61:407-, 2005
PubMed: 15805595 (PDB entries with the same primary citation)
DOI: 10.1107/S090744490500082X
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.5 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliers 0.3242000MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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More Biological unit images

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(*)In the case of coarse surface representation, the asymmetric unit is shown as red ribbon representation.
Coordinate files for Biological unit (1unj.pdb2.gz [25.75 KB])
Coordinate files for Biological unit (1unj.pdb1.gz [25.3 KB])