5JFX
 
 | | Crystal structure of TrkA in complex with PF-06273340 | | 分子名称: | High affinity nerve growth factor receptor, N-{5-[2-amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl]pyridin-3-yl}-2-(5-chloropyridin-2-yl)acetamide | | 著者 | Jayasankar, J, Kurumbail, R, Skerratt, S, Brown, D. | | 登録日 | 2016-04-19 | | 公開日 | 2017-03-01 | | 最終更新日 | 2024-03-06 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | The Discovery of a Potent, Selective, and Peripherally Restricted Pan-Trk Inhibitor (PF-06273340) for the Treatment of Pain.
J. Med. Chem., 59, 2016
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1WKD
 | | TRNA-GUANINE TRANSGLYCOSYLASE | | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | | 登録日 | 1996-08-06 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
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1WKE
 | | TRNA-GUANINE TRANSGLYCOSYLASE | | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | | 登録日 | 1996-08-06 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
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1WKF
 | | TRNA-GUANINE TRANSGLYCOSYLASE | | 分子名称: | TRNA-GUANINE TRANSGLYCOSYLASE, ZINC ION | | 著者 | Romier, C, Reuter, K, Suck, D, Ficner, R. | | 登録日 | 1996-08-06 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mutagenesis and crystallographic studies of Zymomonas mobilis tRNA-guanine transglycosylase reveal aspartate 102 as the active site nucleophile.
Biochemistry, 35, 1996
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4IYM
 | | Crystal structure of putative methylmalonate-semialdehyde dehydrogenase from Sinorhizobium meliloti 1021 complexed with NAD, target 011934 | | 分子名称: | MAGNESIUM ION, Methylmalonate-semialdehyde dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Zenchek, W, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-01-28 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Crystal structure of putative methylmalonate-semialdehyde dehydrogenase from Sinorhizobium meliloti 1021 complexed with NAD, target 011934
To be Published
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1X9X
 | | Solution Structure of Dimeric SAM Domain from MAPKKK Ste11 | | 分子名称: | Serine/threonine-protein kinase STE11 | | 著者 | Bhattacharjya, S, Xu, P, Gingras, R, Shaykhutdinov, R, Wu, C, Whiteway, M, Ni, F. | | 登録日 | 2004-08-24 | | 公開日 | 2005-08-30 | | 最終更新日 | 2024-05-22 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Solution structure of the dimeric SAM domain of MAPKKK Ste11 and its interactions with the adaptor protein Ste50 from the budding yeast: implications for Ste11 activation and signal transmission through the Ste50-Ste11 complex.
J.Mol.Biol., 344, 2004
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1XBW
 | | 1.9A Crystal Structure of the protein isdG from Staphylococcus aureus aureus, Structural genomics, MCSG | | 分子名称: | hypothetical protein isdG | | 著者 | Zhang, R, Wu, R, Joachimiak, G, Schneewind, O, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-08-31 | | 公開日 | 2004-10-12 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Staphylococcus aureus IsdG and IsdI, heme-degrading enzymes with structural similarity to monooxygenases.
J.Biol.Chem., 280, 2005
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4IX1
 | | Crystal structure of hypothetical protein OPAG_01669 from Rhodococcus Opacus PD630, Target 016205 | | 分子名称: | PHOSPHATE ION, hypothetical protein | | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Zenchek, W, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-01-24 | | 公開日 | 2013-02-06 | | 最終更新日 | 2013-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Crystal structure of hypothetical protein OPAG_01669 from Rhodococcus Opacus PD630, Target 016205
To be Published
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5K7F
 | | Crystal structure of apo AibR | | 分子名称: | ACETATE ION, Transcriptional regulator, TetR family | | 著者 | Bock, T, Volz, C, Mueller, R, Blankenfeldt, W. | | 登録日 | 2016-05-26 | | 公開日 | 2016-12-21 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The AibR-isovaleryl coenzyme A regulator and its DNA binding site - a model for the regulation of alternative de novo isovaleryl coenzyme A biosynthesis in Myxococcus xanthus.
Nucleic Acids Res., 45, 2017
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6VRS
 | | Single particle reconstruction of glucose isomerase from Streptomyces rubiginosus based on data acquired in the presence of substantial aberrations | | 分子名称: | MANGANESE (II) ION, xylose isomerase | | 著者 | Bromberg, R, Guo, Y, Borek, D, Otwinowski, Z. | | 登録日 | 2020-02-09 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | High-resolution cryo-EM reconstructions in the presence of substantial aberrations
Iucrj, 7, 2020
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1KEB
 | | Crystal Structure of Double Mutant M37L,P40S E.coli Thioredoxin | | 分子名称: | COPPER (II) ION, Thioredoxin 1 | | 著者 | Rudresh, Jain, R, Dani, V, Mitra, A, Srivastava, S, Sarma, S.P, Varadarajan, R, Ramakumar, S. | | 登録日 | 2001-11-15 | | 公開日 | 2002-11-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structural Consequences of Replacement of an alpha-helical Pro Residue in E.coli Thioredoxin
PROTEIN ENG., 15, 2002
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1XDZ
 | | Crystal Structure of Gram_Positive Bacillus subtilis Glucose inhibited Division protein B (gidB), Structural genomics, MCSG | | 分子名称: | Methyltransferase gidB | | 著者 | Zhang, R, Wu, R, Collart, F, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) | | 登録日 | 2004-09-08 | | 公開日 | 2004-10-26 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The 1.6A crystal ctructure of Gram-positive Bacillus subtilis glucose inhibited division protein B (gidB)
To be Published
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6VSC
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1KPK
 | | Crystal Structure of the ClC Chloride Channel from E. coli | | 分子名称: | putative channel transporter | | 著者 | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | 登録日 | 2001-12-31 | | 公開日 | 2002-01-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
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1KPL
 | | Crystal Structure of the ClC Chloride Channel from S. typhimurium | | 分子名称: | CHLORIDE ION, N-OCTANE, PENTADECANE, ... | | 著者 | Dutzler, R, Campbell, E.B, Cadene, M, Chait, B.T, MacKinnon, R. | | 登録日 | 2001-12-31 | | 公開日 | 2002-01-23 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | X-ray structure of a ClC chloride channel at 3.0 A reveals the molecular basis of
anion selectivity.
Nature, 415, 2002
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1NJT
 | | COMPLEX STRUCTURE OF HCMV PROTEASE AND A PEPTIDOMIMETIC INHIBITOR | | 分子名称: | CHLORIDE ION, Capsid protein P40, Peptidomimetic Inhibitor | | 著者 | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | | 登録日 | 2003-01-02 | | 公開日 | 2003-02-11 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
Biochemistry, 42, 2003
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5KAL
 | | Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UpU | | 分子名称: | MAGNESIUM ION, RNA (5'-R(*UP*U)-3'), RNA uridylyltransferase 4, ... | | 著者 | Stagno, J.R, Luecke, H, Afasizhev, R. | | 登録日 | 2016-06-01 | | 公開日 | 2016-10-26 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | | 主引用文献 | RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.
Nucleic Acids Res., 44, 2016
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1NJU
 | | Complex structure of HCMV Protease and a peptidomimetic inhibitor | | 分子名称: | Assemblin, N-(6-aminohexanoyl)-3-methyl-L-valyl-3-methyl-L-valyl-N~1~-[(2S,3S)-3-hydroxy-4-oxo-4-{[(1R)-1-phenylpropyl]amino}butan-2-yl]-N~4~,N~4~-dimethyl-L-aspartamide | | 著者 | Khayat, R, Batra, R, Qian, C, Halmos, T, Bailey, M, Tong, L. | | 登録日 | 2003-01-02 | | 公開日 | 2003-02-11 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Structural and Biochemical Studies of Inhibitor Binding to Human Cytomegalovirus Protease
Biochemistry, 42, 2003
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4JKS
 | | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with DMSO, NYSGRC Target 14306 | | 分子名称: | ADENOSINE, DIMETHYL SULFOXIDE, Probable sugar kinase protein | | 著者 | Malashkevich, V.N, Bhosle, R, Toro, R, Hillerich, B, Gizzi, A, Garforth, S, Kar, A, Chan, M.K, Lafluer, J, Patel, H, Matikainen, B, Chamala, S, Lim, S, Celikgil, A, Villegas, G, Evans, B, Love, J, Fiser, A, Khafizov, K, Seidel, R, Bonanno, J.B, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC) | | 登録日 | 2013-03-11 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Crystal structure of probable sugar kinase protein from Rhizobium etli CFN 42 complexed with DMSO, NYSGRC Target 14306
To be Published
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7LA6
 | | THE STRUCTURE OF A SENSOR DOMAIN OF A HISTIDINE KINASE (VxrA) FROM VIBRIO CHOLERAE O1 BIOVAR ELTOR STR. N16961, N239 deletion mutant | | 分子名称: | DI(HYDROXYETHYL)ETHER, GLYCEROL, SULFATE ION, ... | | 著者 | Tan, K, Wu, R, Jedrzejczak, R, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2021-01-05 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Sensor Domain of Histidine Kinase VxrA of Vibrio cholerae - A Hairpin-swapped Dimer and its Conformational Change.
J.Bacteriol., 203, 2021
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1NJM
 | | The crystal structure of the 50S Large ribosomal subunit from Deinococcus radiodurans complexed with a tRNA acceptor stem mimic (ASM) and the antibiotic sparsomycin | | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L16, GENERAL STRESS PROTEIN CTC, ... | | 著者 | Bashan, A, Agmon, I, Zarivatch, R, Schluenzen, F, Harms, J.M, Berisio, R, Bartels, H, Hansen, H.A, Yonath, A. | | 登録日 | 2003-01-02 | | 公開日 | 2003-02-11 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | Structural basis of the ribosomal machinery for Peptide bond formation,
translocation, and nascent chain progression
Mol.Cell, 11, 2003
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1JV2
 | | CRYSTAL STRUCTURE OF THE EXTRACELLULAR SEGMENT OF INTEGRIN ALPHAVBETA3 | | 分子名称: | 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Xiong, J.P, Stehle, T, Diefenbach, B, Zhang, R, Dunker, R, Scott, D, Joachimiak, A, Goodman, S.L, Arnaout, M.A. | | 登録日 | 2001-08-28 | | 公開日 | 2001-10-17 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of the extracellular segment of integrin alpha Vbeta3.
Science, 294, 2001
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1YJO
 | | Structure of NNQQNY from yeast prion Sup35 with zinc acetate | | 分子名称: | ACETIC ACID, Eukaryotic peptide chain release factor GTP-binding subunit, ZINC ION | | 著者 | Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D. | | 登録日 | 2005-01-15 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005
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1YJP
 | | Structure of GNNQQNY from yeast prion Sup35 | | 分子名称: | Eukaryotic peptide chain release factor GTP-binding subunit | | 著者 | Nelson, R, Sawaya, M.R, Balbirnie, M, Madsen, A.O, Riekel, C, Grothe, R, Eisenberg, D. | | 登録日 | 2005-01-15 | | 公開日 | 2005-06-14 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structure of the cross-beta spine of amyloid-like fibrils.
Nature, 435, 2005
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1YKQ
 | | Crystal structure of Diels-Alder ribozyme | | 分子名称: | CADMIUM ION, Diels-Alder ribozyme, MAGNESIUM ION | | 著者 | Serganov, A, Keiper, S, Malinina, L, Tereshko, V, Skripkin, E, Hobartner, C, Polonskaia, A, Phan, A.T, Wombacher, R, Micura, R, Dauter, Z, Jaschke, A, Patel, D.J. | | 登録日 | 2005-01-18 | | 公開日 | 2005-02-22 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Structural basis for Diels-Alder ribozyme-catalyzed carbon-carbon bond formation.
Nat.Struct.Mol.Biol., 12, 2005
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