Terminal uridylyl transferase 4 from Trypanosoma brucei with bound UTP and UpU

Summary for 5KAL

DescriptorRNA uridylyltransferase 4, RNA (5'-R(*UP*U)-3'), URIDINE 5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywordstrypanosoma, rna editing, tutase, transferase, transferase-rna complex, transferase/rna
Biological sourceTrypanosoma brucei
Total number of polymer chains4
Total molecular weight81983.35
Stagno, J.R.,Luecke, H.,Afasizhev, R. (deposition date: 2016-06-01, release date: 2016-10-26, Last modification date: 2016-12-28)
Primary citation
Rajappa-Titu, L.,Suematsu, T.,Munoz-Tello, P.,Long, M.,Demir, O.,Cheng, K.J.,Stagno, J.R.,Luecke, H.,Amaro, R.E.,Aphasizheva, I.,Aphasizhev, R.,Thore, S.
RNA Editing TUTase 1: structural foundation of substrate recognition, complex interactions and drug targeting.
Nucleic Acids Res., 44:10862-10878, 2016
PubMed: 27744351 (PDB entries with the same primary citation)
DOI: 10.1093/nar/gkw917
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone 0.25910 2.3% 5.1% 0.24MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-10-21