8AGT
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![BU of 8agt by Molmil](/molmil-images/mine/8agt) | Yeast RQC complex in state F | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGZ
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![BU of 8agz by Molmil](/molmil-images/mine/8agz) | Yeast RQC complex in state with the RING domain of Ltn1 in the OUT position | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGV
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![BU of 8agv by Molmil](/molmil-images/mine/8agv) | Yeast RQC complex in state H | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGW
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![BU of 8agw by Molmil](/molmil-images/mine/8agw) | Yeast RQC complex in state D | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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8AGX
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![BU of 8agx by Molmil](/molmil-images/mine/8agx) | Yeast RQC complex in state with the RING domain of Ltn1 in the IN position | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Tesina, P, Buschauer, R, Beckmann, R. | 登録日 | 2022-07-20 | 公開日 | 2023-03-08 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control. Mol.Cell, 83, 2023
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7SWJ
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![BU of 7swj by Molmil](/molmil-images/mine/7swj) | KirBac1.1 mutant - I131C | 分子名称: | Inward rectifier potassium channel | 著者 | Amani, R, Wylie, B.J. | 登録日 | 2021-11-19 | 公開日 | 2022-02-02 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Water Accessibility Refinement of the Extended Structure of KirBac1.1 in the Closed State. Front Mol Biosci, 8, 2021
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4YW7
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![BU of 4yw7 by Molmil](/molmil-images/mine/4yw7) | Structural Insight into Divalent Galactoside Binding to Pseudomonas aeruginosa lectin LecA | 分子名称: | (2R,3R,4S,5R,6R,2'R,3'R,4'S,5'R,6'R)-2,2'-([(2R,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2,5-diyl]bis{1H-1,2,3-triazole-1,4-diyl[(2S,3R,4S,5S,6S)-3,4-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2,5-diyl]-1H-1,2,3-triazole-1,4-diylpropane-3,1-diyloxy})bis[6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol], CALCIUM ION, PA-I galactophilic lectin, ... | 著者 | Visini, R, Jin, X, Michaud, G, Bergmann, M, Gillon, E, Imberty, A, Stocker, A, Darbre, T, Pieters, R, Reymond, J.-L. | 登録日 | 2015-03-20 | 公開日 | 2015-09-09 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Structural Insight into Multivalent Galactoside Binding to Pseudomonas aeruginosa Lectin LecA. Acs Chem.Biol., 10, 2015
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1SAV
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![BU of 1sav by Molmil](/molmil-images/mine/1sav) | HUMAN ANNEXIN V WITH PROLINE SUBSTITUTION BY THIOPROLINE | 分子名称: | ANNEXIN V, CALCIUM ION | 著者 | Medrano, F.J, Minks, C, Budisa, N, Huber, R. | 登録日 | 1997-11-24 | 公開日 | 1998-05-27 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal and molecular structure of human annexin V after refinement. Implications for structure, membrane binding and ion channel formation of the annexin family of proteins. J.Mol.Biol., 223, 1992
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7TLA
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![BU of 7tla by Molmil](/molmil-images/mine/7tla) | |
5AAG
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![BU of 5aag by Molmil](/molmil-images/mine/5aag) | Aurora A kinase bound to an imidazopyridine inhibitor (14b) | 分子名称: | AURORA KINASE A, [3-[[4-[6-chloranyl-2-(1,3-dimethylpyrazol-4-yl)-3H-imidazo[4,5-b]pyridin-7-yl]pyrazol-1-yl]methyl]phenyl]-(4-methylpiperazin-1-yl)methanone | 著者 | McIntyre, P.J, Bayliss, R. | 登録日 | 2015-07-24 | 公開日 | 2015-09-02 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | 7-(Pyrazol-4-Yl)-3H-Imidazo[4,5-B]Pyridine-Based Derivatives for Kinase Inhibition: Co-Crystallisation Studies with Aurora-A Reveal Distinct Differences in the Orientation of the Pyrazole N1-Substituent. Bioorg.Med.Chem.Lett., 25, 2015
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7TLD
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![BU of 7tld by Molmil](/molmil-images/mine/7tld) | |
7TLB
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![BU of 7tlb by Molmil](/molmil-images/mine/7tlb) | |
7TLC
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![BU of 7tlc by Molmil](/molmil-images/mine/7tlc) | |
3ZJV
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![BU of 3zjv by Molmil](/molmil-images/mine/3zjv) | Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation | 分子名称: | LEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR | 著者 | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | 登録日 | 2013-01-18 | 公開日 | 2013-04-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | 主引用文献 | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
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7QKB
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![BU of 7qkb by Molmil](/molmil-images/mine/7qkb) | Crystal structure of human Cathepsin L in complex with covalently bound GC376 | 分子名称: | CHLORIDE ION, Cathepsin L, DI(HYDROXYETHYL)ETHER, ... | 著者 | Reinke, P.Y.A, Falke, S, Lieske, J, Ewert, W, Loboda, J, Rahmani Mashhour, A, Hauser, M, Karnicar, K, Usenik, A, Lindic, N, Lach, M, Boehler, H, Beck, T, Cox, R, Chapman, H.N, Hinrichs, W, Turk, D, Guenther, S, Meents, A. | 登録日 | 2021-12-17 | 公開日 | 2022-12-28 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Calpeptin is a potent cathepsin inhibitor and drug candidate for SARS-CoV-2 infections. Commun Biol, 6, 2023
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3ZJT
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![BU of 3zjt by Molmil](/molmil-images/mine/3zjt) | Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation | 分子名称: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | 著者 | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | 登録日 | 2013-01-18 | 公開日 | 2013-04-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
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6SVF
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![BU of 6svf by Molmil](/molmil-images/mine/6svf) | Crystal structure of the P235GK mutant of ArgBP from T. maritima | 分子名称: | ARGININE, Amino acid ABC transporter, periplasmic amino acid-binding protein | 著者 | Vitagliano, L, Berisio, R, Esposito, L, Balasco, N, Smaldone, G, Ruggiero, A. | 登録日 | 2019-09-18 | 公開日 | 2019-11-20 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | The non-swapped monomeric structure of the arginine-binding protein from Thermotoga maritima. Acta Crystallogr.,Sect.F, 75, 2019
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4C4E
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![BU of 4c4e by Molmil](/molmil-images/mine/4c4e) | Structure-based design of orally bioavailable pyrrolopyridine inhibitors of the mitotic kinase MPS1 | 分子名称: | 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, DUAL SPECIFICITY PROTEIN KINASE TTK, N-(3,4-dimethoxyphenyl)-2-(1H-pyrazol-4-yl)-1H-pyrrolo[3,2-c]pyridin-6-amine, ... | 著者 | Naud, S, Westwood, I.M, Faisal, A, Sheldrake, P, Bavetsias, V, Atrash, B, Liu, M, Hayes, A, Schmitt, J, Wood, A, Choi, V, Boxall, K, Mak, G, Gurden, M, Valenti, M, de Haven Brandon, A, Henley, A, Baker, R, McAndrew, C, Matijssen, B, Burke, R, Eccles, S.A, Raynaud, F.I, Linardopoulos, S, van Montfort, R, Blagg, J. | 登録日 | 2013-09-05 | 公開日 | 2013-12-04 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Structure-Based Design of Orally Bioavailable 1H-Pyrrolo[3, 2-C]Pyridine Inhibitors of the Mitotic Kinase Monopolar Spindle 1 (Mps1). J.Med.Chem., 56, 2013
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1MZI
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![BU of 1mzi by Molmil](/molmil-images/mine/1mzi) | Solution ensemble structures of HIV-1 gp41 2F5 mAb epitope | 分子名称: | 2F5 epitope of HIV-1 gp41 fusion protein | 著者 | Barbato, G, Bianchi, E, Ingallinella, P, Hurni, W.H, Miller, M.D, Ciliberto, G, Cortese, R, Bazzo, R, Shiver, J.W, Pessi, A. | 登録日 | 2002-10-08 | 公開日 | 2003-09-02 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion. J.Mol.Biol., 330, 2003
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6SV2
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![BU of 6sv2 by Molmil](/molmil-images/mine/6sv2) | |
8AZW
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![BU of 8azw by Molmil](/molmil-images/mine/8azw) | Cryo-EM structure of the plant 60S subunit | 分子名称: | 25S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-09-06 | 公開日 | 2023-06-07 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.14 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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8AUV
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![BU of 8auv by Molmil](/molmil-images/mine/8auv) | Cryo-EM structure of the plant 40S subunit | 分子名称: | 18S rRNA, MAGNESIUM ION, POTASSIUM ION, ... | 著者 | Smirnova, J, Loerke, J, Kleinau, G, Schmidt, A, Buerger, J, Meyer, E.H, Mielke, T, Scheerer, P, Bock, R, Spahn, C.M.T, Zoschke, R. | 登録日 | 2022-08-25 | 公開日 | 2023-06-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Structure of the actively translating plant 80S ribosome at 2.2 angstrom resolution. Nat.Plants, 9, 2023
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3ZJU
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![BU of 3zju by Molmil](/molmil-images/mine/3zju) | Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3016 in the editing conformation | 分子名称: | LEUCYL-TRNA SYNTHETASE, MAGNESIUM ION, TRNALEU5 UAA ISOACCEPTOR | 著者 | Cusack, S, Palencia, A, Crepin, T, Hernandez, V, Akama, T, Baker, S.J, Bu, W, Feng, L, Freund, Y.R, Liu, L, Meewan, M, Mohan, M, Mao, W, Rock, F.L, Sexton, H, Sheoran, A, Zhang, Y, Zhang, Y, Zhou, Y, Nieman, J.A, Anugula, M.R, Keramane, E.M, Savariraj, K, Reddy, D.S, Sharma, R, Subedi, R, Singh, R, OLeary, A, Simon, N.L, DeMarsh, P.L, Mushtaq, S, Warner, M, Livermore, D.M, Alley, M.R.K, Plattner, J.J. | 登録日 | 2013-01-18 | 公開日 | 2013-04-17 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother., 57, 2013
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7ZW0
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![BU of 7zw0 by Molmil](/molmil-images/mine/7zw0) | FAP-80S Complex - Rotated state | 分子名称: | 18S ribosomal RNA (RDN18-1), 25S ribosomal RNA (RDN25-1), 40S ribosomal protein S0-A, ... | 著者 | Ikeuchi, K, Buschauer, R, Berninghausen, O, Becker, T, Beckmann, R. | 登録日 | 2022-05-17 | 公開日 | 2022-10-05 | 最終更新日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover. Mol.Cell, 82, 2022
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7ZGO
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![BU of 7zgo by Molmil](/molmil-images/mine/7zgo) | Cryo-EM structure of human NKCC1 (TM domain) | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Nissen, P, Fenton, R, Neumann, C, Lindtoft Rosenbaek, L, Kock Flygaard, R, Habeck, M, Lykkegaard Karlsen, J, Wang, Y, Lindorff-Larsen, K, Gad, H, Hartmann, R, Lyons, J. | 登録日 | 2022-04-04 | 公開日 | 2022-10-05 | 最終更新日 | 2023-04-19 | 実験手法 | ELECTRON MICROSCOPY (2.55 Å) | 主引用文献 | Cryo-EM structure of the human NKCC1 transporter reveals mechanisms of ion coupling and specificity. Embo J., 41, 2022
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