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3ZJV

Ternary complex of E .coli leucyl-tRNA synthetase, tRNA(Leu) and the benzoxaborole AN3213 in the editing conformation

Summary for 3ZJV
Entry DOI10.2210/pdb3zjv/pdb
Related3ZJT 3ZJU
DescriptorLEUCINE--TRNA LIGASE, TRNALEU5 UAA ISOACCEPTOR (3 entities in total)
Functional Keywordsligase-rna complex, ligase, protein biosynthesis, class i aminoacyl-trna synthetase, aminoacyl trna synthetase, atp binding, editing synthetase, ligase/rna
Biological sourceESCHERICHIA COLI
More
Cellular locationCytoplasm: P07813
Total number of polymer chains2
Total formula weight127786.71
Authors
Primary citationHernandez, V.,Crepin, T.,Palencia, A.,Cusack, S.,Akama, T.,Baker, S.J.,Bu, W.,Feng, L.,Freund, Y.R.,Liu, L.,Meewan, M.,Mohan, M.,Mao, W.,Rock, F.L.,Sexton, H.,Sheoran, A.,Zhang, Y.,Zhang, Y.,Zhou, Y.,Nieman, J.A.,Anugula, M.R.,Keramane, E.M.,Savariraj, K.,Reddy, D.S.,Sharma, R.,Subedi, R.,Singh, R.,O'Leary, A.,Simon, N.L.,De Marsh, P.L.,Mushtaq, S.,Warner, M.,Livermore, D.M.,Alley, M.R.K.,Plattner, J.J.
Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57:1394-, 2013
Cited by
PubMed: 23295920
DOI: 10.1128/AAC.02058-12
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.31 Å)
Structure validation

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