3ZJT

Ternary complex of E.coli leucyl-tRNA synthetase, tRNA(Leu)574 and the benzoxaborole AN3017 in the editing conformation

Summary for 3ZJT

Related3ZJU 3ZJV
DescriptorLEUCYL-TRNA SYNTHETASE, TRNALEU5 UAA ISOACCEPTOR, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordsligase-rna complex, nucleotide (atp) -binding, protein biosynthesis, class i aminoacyl-trna synthetase, aminoacyl trna synthetase, atp binding, editing synthetase, ligase/rna
Biological sourceESCHERICHIA COLI
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Cellular locationCytoplasm P07813
Total number of polymer chains2
Total molecular weight128147.76
Authors
Primary citation
Hernandez, V.,Crepin, T.,Palencia, A.,Cusack, S.,Akama, T.,Baker, S.J.,Bu, W.,Feng, L.,Freund, Y.R.,Liu, L.,Meewan, M.,Mohan, M.,Mao, W.,Rock, F.L.,Sexton, H.,Sheoran, A.,Zhang, Y.,Zhang, Y.,Zhou, Y.,Nieman, J.A.,Anugula, M.R.,Keramane, E.M.,Savariraj, K.,Reddy, D.S.,Sharma, R.,Subedi, R.,Singh, R.,O'Leary, A.,Simon, N.L.,De Marsh, P.L.,Mushtaq, S.,Warner, M.,Livermore, D.M.,Alley, M.R.K.,Plattner, J.J.
Discovery of a Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria.
Antimicrob.Agents Chemother., 57:1394-, 2013
PubMed: 23295920 (PDB entries with the same primary citation)
DOI: 10.1128/AAC.02058-12
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.2 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliersRNA backbone0.249110.1%4.1%7.3%0.37MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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