7TLC

Down-state locked, S2 stabilized rS2d-HexaPro SARS-CoV-2 spike ectodomain in the RBD-down conformation, State 1

Summary for 7TLC

Entry DOI	10.2210/pdb7tlc/pdb
EMDB information	25987
Descriptor	Spike glycoprotein (1 entity in total)
Functional Keywords	spike, fusion protein, viral protein
Biological source	Severe acute respiratory syndrome coronavirus 2
Total number of polymer chains	3
Total formula weight	401356.27
Authors	Henderson, R.,Acharya, P. (deposition date: 2022-01-18, release date: 2022-02-02, Last modification date: 2023-04-12)
Primary citation	Gobeil, S.M.,Henderson, R.,Stalls, V.,Janowska, K.,Huang, X.,May, A.,Speakman, M.,Beaudoin, E.,Manne, K.,Li, D.,Parks, R.,Barr, M.,Deyton, M.,Martin, M.,Mansouri, K.,Edwards, R.J.,Eaton, A.,Montefiori, D.C.,Sempowski, G.D.,Saunders, K.O.,Wiehe, K.,Williams, W.,Korber, B.,Haynes, B.F.,Acharya, P. Structural diversity of the SARS-CoV-2 Omicron spike. Mol.Cell, 82:2050-2068.e6, 2022 Cited by PubMed: 35447081 DOI: 10.1016/j.molcel.2022.03.028 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.83 Å)

Structure validation