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PDB: 21 件
3EHT
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Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF
分子名称: Corticoliberin, FUSION PROTEIN OF CRFR1 EXTRACELLULAR DOMAIN AND MBP, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pioszak, A.A, Xu, H.E.
登録日2008-09-14
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
3EHS
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Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1)
分子名称: alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, fusion protein of CRFR1 extracellular domain and MBP
著者Pioszak, A.A, Xu, H.E.
登録日2008-09-14
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.76 Å)
主引用文献Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
1WN9
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Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
分子名称: ACETIC ACID, the hypothetical protein (TT1805)
著者Pioszak, A.A, Kishishita, S, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-07-28
公開日2005-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
To be Published
1WXX
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Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8
分子名称: PHOSPHATE ION, POTASSIUM ION, hypothetical protein TTHA1280
著者Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-02-02
公開日2005-08-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
1WNA
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BU of 1wna by Molmil
Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
分子名称: the hypothetical protein (TT1805)
著者Pioszak, A.A, Kishishita, S, Shirouzu, M, Kuramitsu, S, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-07-28
公開日2005-01-28
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of the hypothetical protein TT1805 from Thermus thermophillus HB8
To be Published
1WXW
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BU of 1wxw by Molmil
Crystal structure of Tt1595, a putative SAM-dependent methyltransferase from Thermus thermophillus HB8
分子名称: HEXANE-1,6-DIOL, hypothetical protein TTHA1280
著者Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-02-02
公開日2005-08-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
3H3G
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BU of 3h3g by Molmil
Crystal structure of the extracellular domain of the human parathyroid hormone receptor (PTH1R) in complex with parathyroid hormone-related protein (PTHrP)
分子名称: Fusion protein of Maltose-binding periplasmic domain and human parathyroid hormone receptor extracellular domain, Parathyroid hormone-related protein, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pioszak, A.A, Xu, H.E.
登録日2009-04-16
公開日2009-08-11
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.94 Å)
主引用文献Structural basis for parathyroid hormone-related protein binding to the parathyroid hormone receptor and design of conformation-selective peptides.
J.Biol.Chem., 284, 2009
3C4M
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Structure of human parathyroid hormone in complex with the extracellular domain of its G-protein-coupled receptor (PTH1R)
分子名称: Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, Parathyroid hormone, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pioszak, A.A, Xu, H.E.
登録日2008-01-30
公開日2008-04-08
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Molecular recognition of parathyroid hormone by its G protein-coupled receptor.
Proc.Natl.Acad.Sci.Usa, 105, 2008
3EHU
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Crystal structure of the extracellular domain of human corticotropin releasing factor receptor type 1 (CRFR1) in complex with CRF
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Corticoliberin, ...
著者Pioszak, A.A, Xu, H.E.
登録日2008-09-14
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Molecular Recognition of Corticotropin-releasing Factor by Its G-protein-coupled Receptor CRFR1.
J.Biol.Chem., 283, 2008
2CWZ
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BU of 2cwz by Molmil
Crystal structure of the Thermus thermophilus hypothetical protein TTHA0967, a thioesterase superfamily member
分子名称: 1,2-ETHANEDIOL, thioesterase family protein
著者Pioszak, A.A, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-27
公開日2005-12-27
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the Thermus thermophilus hypothetical protein TTHA0967, a thioesterase superfamily member
To be Published
2CXK
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Crystal structure of the TIG domain of human calmodulin-binding transcription activator 1 (CAMTA1)
分子名称: SULFATE ION, calmodulin binding transcription activator 1
著者Pioszak, A.A, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-30
公開日2005-12-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Crystal structure of the TIG domain of human calmodulin-binding transcription activator 1 (CAMTA1)
To be Published
2CWW
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BU of 2cww by Molmil
Crystal structure of Thermus thermophilus TTHA1280, a putative SAM-dependent RNA methyltransferase, in complex with S-adenosyl-L-homocysteine
分子名称: ACETIC ACID, GLYCEROL, S-ADENOSYL-L-HOMOCYSTEINE, ...
著者Pioszak, A.A, Murayama, K, Nakagawa, N, Ebihara, A, Kuramitsu, S, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-06-27
公開日2005-10-11
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of a putative RNA 5-methyluridine methyltransferase, Thermus thermophilus TTHA1280, and its complex with S-adenosyl-L-homocysteine.
Acta Crystallogr.,Sect.F, 61, 2005
3L2J
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BU of 3l2j by Molmil
Dimeric structure of the ligand-free extracellular domain of the human parathyroid hormone receptor (PTH1R)
分子名称: Fusion protein of Maltose-binding periplasmic protein and Parathyroid hormone/parathyroid hormone-related peptide receptor, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pioszak, A.A, Xu, H.E.
登録日2009-12-15
公開日2010-02-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (3.24 Å)
主引用文献Dimeric arrangement of the parathyroid hormone receptor and a structural mechanism for ligand-induced dissociation.
J.Biol.Chem., 285, 2010
6PFO
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BU of 6pfo by Molmil
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (16-32)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Calcitonin, Maltodextrin-binding protein,Calcitonin receptor, ...
著者Lee, S, Pioszak, A.A.
登録日2019-06-21
公開日2020-02-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
J.Mol.Biol., 432, 2020
6PGQ
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BU of 6pgq by Molmil
Crystal structure of N-glycosylated human calcitonin receptor extracellular domain in complex with salmon calcitonin (22-32)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Calcitonin, ...
著者Lee, S, Pioszak, A.A.
登録日2019-06-24
公開日2020-02-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics.
J.Mol.Biol., 432, 2020
6V2E
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BU of 6v2e by Molmil
Crystal structure of the human CLR:RAMP2 extracellular domain heterodimer with bound high-affinity adrenomedullin S45R/K46L/S48G/Q50W variant
分子名称: ADM, AMINO GROUP, FORMIC ACID, ...
著者Booe, J.M, Pioszak, A.A.
登録日2019-11-22
公開日2020-08-05
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Picomolar Affinity Antagonist and Sustained Signaling Agonist Peptide Ligands for the Adrenomedullin and Calcitonin Gene-Related Peptide Receptors.
Acs Pharmacol Transl Sci, 3, 2020
1R62
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BU of 1r62 by Molmil
Crystal structure of the C-terminal Domain of the Two-Component System Transmitter Protein NRII (NtrB)
分子名称: Nitrogen regulation protein NR(II)
著者Song, Y, Peisach, D, Pioszak, A.A, Xu, Z, Ninfa, A.J.
登録日2003-10-14
公開日2004-06-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of the C-terminal Domain of the Two-Component System Transmitter Protein Nitrogen Regulator II (NRII; NtrB), Regulator of Nitrogen Assimilation in Escherichia coli.
Biochemistry, 43, 2004
3N96
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Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 1
分子名称: Maltose binding protein-CRFR2 alpha, Urocortin, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N93
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Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 3
分子名称: GLYCEROL, Maltose binding protein-CRFR2 alpha, Urocortin-3, ...
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N95
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Crystal structure of human CRFR2 alpha extracellular domain in complex with Urocortin 2
分子名称: Maltose binding protein-CRFR2 alpha extracellular domain, Urocortin-2, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Pal, K, Swaminathan, K, Pioszak, A.A, Xu, H.E.
登録日2010-05-28
公開日2010-10-20
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.72 Å)
主引用文献Structural basis of ligand selectivity in human CRFR1 and CRFR2 alpha extracellular domain
To be Published
3N94
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Crystal structure of human pituitary adenylate cyclase 1 Receptor-short N-terminal extracellular domain
分子名称: Fusion protein of Maltose-binding periplasmic protein and pituitary adenylate cyclase 1 Receptor-short, SULFATE ION, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose
著者Kumar, S, Pioszak, A.A, Swaminathan, K, Xu, H.E.
登録日2010-05-28
公開日2011-06-08
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal Structure of the PAC1R Extracellular Domain Unifies a Consensus Fold for Hormone Recognition by Class B G-Protein Coupled Receptors.
Plos One, 6, 2011

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